7182762

Glycophorin A, Rabbit anti-Human, Clone: M2A1, Novus Biologicals™

Rabbit Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Glycophorin A

Concentration

1 mg/mL

Applications

ELISA, Immunoblot, Inhibition Assays

Conjugate

Unconjugated

Host Species

Rabbit

Research Discipline

Cancer, Signal Transduction

Formulation

PBS

Gene ID (Entrez)

2993

Immunogen

M2A1 was prepared by immunzing BALB/c mice with human red blood cells of the M phenotype, and was screened by testing for anti-M activity.

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Clone

M2A1

Dilution

ELISA, Immunoblotting, Functional (Inhibition)

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Target Species

Human

Gene Alias

CD235a antigen, glycophorin A (includes MN blood group), glycophorin A (MNS blood group), glycophorin Erik, glycophorin MiI, glycophorin MiIII, glycophorin MiV, glycophorin MiX, glycophorin SAT, glycophorin Sta type C, glycophorin-A, GPA, GPErik, GpMiIII, GPSAT, HGpMiIII, HGpMiV, HGpMiX, HGpMiXI, HGpSta(C), Mi.V glycoprotein (24 AA), MN sialoglycoprotein, MNS, PAS-2, recombinant glycophorin A-B Miltenberger-DR

Gene Symbols

GYPA

Isotype

IgG κ

Purification Method

Protein A purified

Test Specificity

M2A1 binds specifically to the M antigen on human erythrocytes, and shows no reactivity to N antigen. The epitope for this antibody includes the amino-terminal serine residue and sialic acid residues of glycophorin A. The reactivity of M2A1 for M antigen is pH- and salt-dependent (optimum ∽ pH8-9). Blood group antigen M is located on the major sialoglycoprotein (glycophorin A) of red blood cells.

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Description

  • Glycophorin A Monoclonal specifically detects Glycophorin A in Human samples
  • It is validated for ELISA, Immunoblotting, Functional (Inhibition).

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7182762

Rabbit Monoclonal Antibody...


Antigen:
Glycophorin A

Concentration:
1 mg/mL

Applications:
ELISA, Immunoblot, Inhibition Assays

Conjugate:
Unconjugated

Host Species:
Rabbit

Research Discipline:
Cancer, Signal Transduction

Formulation:
PBS

Gene ID (Entrez):
2993

Immunogen:
M2A1 was prepared by immunzing BALB/c mice with human red blood cells of the M phenotype, and was screened by testing for anti-M activity.

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Clone:
M2A1

Dilution:
ELISA, Immunoblotting, Functional (Inhibition)

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
CD235a antigen, glycophorin A (includes MN blood group), glycophorin A (MNS blood group), glycophorin Erik, glycophorin MiI, glycophorin MiIII, glycophorin MiV, glycophorin MiX, glycophorin SAT, glycophorin Sta type C, glycophorin-A, GPA, GPErik, GpMiIII, GPSAT, HGpMiIII, HGpMiV, HGpMiX, HGpMiXI, HGpSta(C), Mi.V glycoprotein (24 AA), MN sialoglycoprotein, MNS, PAS-2, recombinant glycophorin A-B Miltenberger-DR

Gene Symbols:
GYPA

Isotype:
IgG κ

Purification Method:
Protein A purified

Test Specificity:
M2A1 binds specifically to the M antigen on human erythrocytes, and shows no reactivity to N antigen. The epitope for this antibody includes the amino-terminal serine residue and sialic acid residues of glycophorin A. The reactivity of M2A1 for M antigen is pH- and salt-dependent (optimum ∽ pH8-9). Blood group antigen M is located on the major sialoglycoprotein (glycophorin A) of red blood cells.

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7182763

Mouse Monoclonal Antibody...


Antigen:
CD98

Concentration:
1 mg/mL

Applications:
ELISA, Immunofluorescence, Blocking Assay

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Biologically Active Proteins, Cell Biology, Cellular Markers, Immunology, Lipid and Metabolism, Plasma Membrane Markers, Signal Transduction

Formulation:
PBS

Gene ID (Entrez):
6520

Immunogen:
HBJ127 was obtained from hybridomas generated by the fusion of mouse myeloma cells and spleen cells from mice which had been immunized with T24 hyman bladder cancer cells.

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Clone:
HBJ127

Dilution:
ELISA, Immunocytochemistry/Immunofluorescence, Block/Neutralize

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
4F2, 4F2hc, 4T2HC, antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43,4F2HC, CD98, CD98 antigen, CD98 heavy chain, CD98HC, heavy chain, Lymphocyte activation antigen 4F2 large subunit, MDU1antigen defined by monoclonal 4F2, heavy chain, monoclonal 44D7, NACAE4F2 cell-surface antigen heavy chain, solute carrier family 3 (activators of dibasic and neutral amino acidtransport), member 2,4F2 heavy chain antigen

Gene Symbols:
SLC3A2

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
HBJ127 binds to the CD98 heavy chain at an epitope consisting of residues AFS (aa 442-444) (Itoh et al, 2007). The antibody has not been shown to cross-react with other species. CD98 is expressed at high levels on monocytes and at very low level on peripheral blood T and B lymphocytes, splenocytes, NK cells and granulocytes. CD98 is a disulfide-linked and glycosylated type II integral membrane protein. This protein has roles in normal and neoplastic cell growth and is required for the function of light chain amino acid transporters. It is also involved in sodium-independent transport of large neitral amino acids and in guiding and targeting LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7, CD98 acts as an arginine/glutamine exchanger.

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7182765

Mouse Monoclonal Antibody...


Antigen:
Fibrinopeptide B

Concentration:
1 mg/mL

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cell Cycle and Replication

Formulation:
PBS

Gene ID (Entrez):
2244

Immunogen:
8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Clone:
800000

Dilution:
ELISA, In vivo assay

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
fibrinogen beta chain, fibrinogen, B beta polypeptide, MGC104327, MGC120405

Gene Symbols:
FGB

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
8E5 binds to the amino-terminal region of the beta-chain of human fibrin at an epitope consiting of GHRPLDKC. Binding is possible in both the monomeric form and the polymeric form of the protein. This peptide sequence is found only in fibrin, and not in its precursor fibrinogen and so there is no cross-reactivity with fibrinogen. Fibrin is a non-globular protein which plays a role in the clotting of blood and circulates as the precursor fibrinogen. Polymerization occurs through the action of the protease thrombin, which results in the active fibrin. Fibrin polymerizes as an insoluble matrix and forms a clot along with platelets over a wound site.

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Mouse Monoclonal Antibody...


Antigen:
Fibrinopeptide B

Concentration:
1 mg/mL

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Research Discipline:
Cell Cycle and Replication

Formulation:
PBS

Gene ID (Entrez):
2244

Immunogen:
8E5 was prepared fusing Sp2/o myeloma cells with spleen cells derived from female BALB/c mice immunized with a synthetic beta-fibrin peptide seqeunce GHRPLDKC conjugated to MB-KLH (maleimidobenzoylated keyhole limpet hemocyanin).

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Clone:
800000

Dilution:
ELISA, In vivo assay

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Target Species:
Human

Gene Alias:
fibrinogen beta chain, fibrinogen, B beta polypeptide, MGC104327, MGC120405

Gene Symbols:
FGB

Isotype:
IgG1 κ

Purification Method:
Protein A purified

Test Specificity:
8E5 binds to the amino-terminal region of the beta-chain of human fibrin at an epitope consiting of GHRPLDKC. Binding is possible in both the monomeric form and the polymeric form of the protein. This peptide sequence is found only in fibrin, and not in its precursor fibrinogen and so there is no cross-reactivity with fibrinogen. Fibrin is a non-globular protein which plays a role in the clotting of blood and circulates as the precursor fibrinogen. Polymerization occurs through the action of the protease thrombin, which results in the active fibrin. Fibrin polymerizes as an insoluble matrix and forms a clot along with platelets over a wound site.