7182771

TIGIT, Armenian Hamster anti-Mouse, Clone: 4D4, Novus Biologicals™

Armenian Hamster Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

TIGIT

Concentration

1 mg/mL

Applications

Flow Cytometry, Blocking Assay

Conjugate

Unconjugated

Host Species

Armenian Hamster

Target Species

Mouse

Gene Alias

T cell immunoreceptor with Ig and ITIM domains, TIGIT, VSIG9, VSTM3, WUCAM

Gene Symbols

TIGIT

Isotype

IgG κ

Purification Method

Protein A purified

Test Specificity

4D4 specifically recognises TIGIT.

Clone

4D4

Dilution

Flow Cytometry, Block/Neutralize

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Formulation

PBS

Gene ID (Entrez)

201633

Immunogen

Armenian hamsters were immunized with recombinant mouse TIGIT tetramers by a combination of s.c. and food pad immunization and booster injections. Draining lymph nodes were fused with Sp2/0-Ag14 cells, selected in HAT (hypoxanthine/aminopterin/thymidine) medium and supernatants were screened for specificity by ELISA and flow cytometry using TIGIT-transfectants.

Primary or Secondary

Primary

Content And Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

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Description

  • TIGIT Monoclonal specifically detects TIGIT in Mouse samples
  • It is validated for Flow Cytometry, Block/Neutralize.

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Fischer Scientific

7182771

Armenian Hamster Monoclonal Antibod...


Antigen:
TIGIT

Concentration:
1 mg/mL

Applications:
Flow Cytometry, Blocking Assay

Conjugate:
Unconjugated

Host Species:
Armenian Hamster

Target Species:
Mouse

Gene Alias:
T cell immunoreceptor with Ig and ITIM domains, TIGIT, VSIG9, VSTM3, WUCAM

Gene Symbols:
TIGIT

Isotype:
IgG κ

Purification Method:
Protein A purified

Test Specificity:
4D4 specifically recognises TIGIT.

Clone:
4D4

Dilution:
Flow Cytometry, Block/Neutralize

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS

Gene ID (Entrez):
201633

Immunogen:
Armenian hamsters were immunized with recombinant mouse TIGIT tetramers by a combination of s.c. and food pad immunization and booster injections. Draining lymph nodes were fused with Sp2/0-Ag14 cells, selected in HAT (hypoxanthine/aminopterin/thymidine) medium and supernatants were screened for specificity by ELISA and flow cytometry using TIGIT-transfectants.

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

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7182774

Rabbit Monoclonal Antibody...


Antigen:
TIM-1/KIM-1/HAVCR

Concentration:
1 mg/mL

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Alias:
HAVCR-1, HAVCRT cell immunoglobin domain and mucin domain protein 1, hepatitis A virus cellular receptor 1, Kidney injury molecule 1, KIM1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIM-1TIM, TIM1TIMD-1, TIMD1T-cell membrane protein 1

Gene Symbols:
HAVCR1

Isotype:
IgG κ

Purification Method:
Protein A purified

Test Specificity:
This antibody is specific for murine TIM-1/KIM-1/HAVCR, a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. TIM-1/KIM-1/HAVCR has been found on activated CD4+ T cells, mast cells, and a subset of B cells. TIM-1/KIM-1/HAVCR is involved in renal injury, tissue homeostasis, and T cell costimulation, and promotes the differentiation of Th2 cells and the production of IL-4. TIM-1/KIM-1/HAVCR can bind several ligands, including Hepatitis A virus, phosphatidylserine, TIM4, IgA, as well as itself.

Clone:
3B3

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS

Gene ID (Entrez):
26762

Immunogen:
This antibody was raised by immunising female Lewis strain rats (Harlan Sprague-Dawley) subcutaneously with mouse TIM-1/KIM-1/HAVCR-Ig in complete Freund's adjuvant (CFA), followed by multiple 'boosting' with mouse TIM-1/KIM-1/HAVCR-Ig in PBS.

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

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7182775

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Antigen:
TL1A/TNFSF15

Concentration:
1 mg/mL

Applications:
Flow Cytometry, Immunofluorescence, Blocking Assay

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Alias:
MGC129934, MGC129935, TL1A, TL1Vascular endothelial cell growth inhibitor, TNF superfamily ligand TL1A, tumor necrosis factor (ligand) superfamily, member 15, tumor necrosis factor ligand superfamily member 15, vascular endothelial growth inhibitor-192A, VEGI192A, VEGITNF ligand-related molecule 1

Gene Symbols:
TNFSF15

Isotype:
IgG κ

Purification Method:
Protein A purified

Test Specificity:
This antibody is specific for TL1A/TNFSF15, a member of the TNF ligand family. TL1A/TNFSF15 is expressed by endothelial cells, tissue macrophages, monocyte-derived dendritic cells, plasma cells and lamina propria-derived lymphocytes. Among peripheral blood cells, TL1A/TNFSF15 has been shown to be expressed predominantly by CD4+CCR9+ lymphocytes. Its expression has been shown to be induced by TNF alpha, IL-1 alpha and IFN gamma.

Clone:
TAN2-2

Dilution:
Flow Cytometry, Immunocytochemistry/Immunofluorescence, Block/Neutralize

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS

Gene ID (Entrez):
9966

Immunogen:
This antibody was raised by immunising rats with a soluble recombinant TL1A/TNFSF15 (T77-L252):Fc protein.

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

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7182778

Rabbit Monoclonal Antibody...


Antigen:
TRANCE/TNFSF11/RANK L

Concentration:
1 mg/mL

Applications:
Flow Cytometry, Immunohistochemistry, Neutralization

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Alias:
CD254, CD254 antigen, OPGLOPTB2, Osteoclast differentiation factor, Osteoprotegerin ligand, RANKLreceptor activator of nuclear factor kappa B ligand, Receptor activator of nuclear factor kappa-B ligand, sOdf, TNF-related activation-induced cytokine, TRANCEODFhRANKL2, tumor necrosis factor (ligand) superfamily, member 11, tumor necrosis factor ligand superfamily member 11

Gene Symbols:
TNFSF11

Isotype:
IgG κ

Purification Method:
Protein A purified

Test Specificity:
This antibody is specific for murine TRANCE/TNFSF11/RANK L.

Clone:
IK22-5

Dilution:
Flow Cytometry, Immunohistochemistry, Neutralization

Classification:
Monoclonal

Form:
Purified

Regulatory Status:
RUO

Formulation:
PBS

Gene ID (Entrez):
8600

Immunogen:
Thus antibody was raised by immunising an SD rat with murine TRANCE/TNFSF11/RANK L-transfected baby hamster kidney cells.

Primary or Secondary:
Primary

Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.