7188385

LexA DNA-binding Domain Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

LexA DNA-binding Domain

Applications

Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Yeast

Immunogen

This LexA DNA-binding Domain antibody was raised against recombinant protein corresponding to full-lengthE. coliLexA.

Primary or Secondary

Primary

Product Type

Antibody

Concentration

Conc. Not Determined

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype

IgG

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

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Description

  • E
  • coli LexA protein inhibits the transcription of the genes belonging to the SOS regulon that are related to DNA repair and cell division by recognizing and binding to the SOS-box sequence
  • LexA‘s self-protease activity is promoted by RecA protein which, responding to DNA damage, is activated by its binding to single-strand DNA accumulated in the cells
  • It is cleaved into two fragments and loses its function as a repressor
  • As the result, the expression of genes belonging to the SOS regulon is induced, and mutagenic activity in the cells are enhanced.

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Fischer Scientific

7188385

Rabbit Polyclonal Antibody...


Antigen:
LexA DNA-binding Domain

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Yeast

Immunogen:
This LexA DNA-binding Domain antibody was raised against recombinant protein corresponding to full-lengthE. coliLexA.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Img

Fischer Scientific

7188388

Rabbit Polyclonal Antibody...


Antigen:
JunB

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Immunogen:
This JunB antibody was raised against a synthetic peptide corresponding to amino acids 28-42 of human JunB.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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7188389

Mouse Monoclonal Antibody...


Antigen:
MMSET / WHSC1

Applications:
ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Immunogen:
This MMSET / WHSC1 antibody was raised against a recombinant protein corresponding to amino acids 1-647 of human MMSET-I.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG2b

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Img

Fischer Scientific

7188389

Mouse Monoclonal Antibody...


Antigen:
MMSET / WHSC1

Applications:
ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Immunogen:
This MMSET / WHSC1 antibody was raised against a recombinant protein corresponding to amino acids 1-647 of human MMSET-I.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG2b

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles