7188399

ETO / RUNX1T1 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

ETO / RUNX1T1

Applications

Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q06455

Gene ID (Entrez)

862

Immunogen

This ETO / RUNX1T1 antibody was raised against a peptide within the internal region of human ETO / RUNX1T1.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

RUNX1T1

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

acute myelogenous leukemia 1 translocation 1 protein; acute myelogenous leukemia 1 translocation 1, cyclin-D related; AML1-MTG8; AML1T1; BOS_14107; Cbfa2t1; CBFA2T1 identified gene homolog; CBFA2T1 isoform r1t1-11a61; CBFA2T1 isoform r1t1-11a62; CBFA2T1 isoform r1t1-11a63; CBFA2T1 isoform r1t1-11a64; CBFA2T1 isoform r1t1-11a65; CBFA2T1 isoform r1t1-7a47; CBFA2T1 isoform r1t1-7a48; CBFA2T1 isoform r1t1-7a49; CBFA2T1 isoform r1t1-7a50; CBFA2T1 isoform r1t1-7a51; CBFA2T1 isoform r1t1-7a52; CBFA2T1 isoform r1t1-7d53; CBFA2T1 isoform r1t1-7d54; CBFA2T1 isoform r1t1-7d55; CBFA2T1 isoform r1t1-7d56; CBFA2T1 isoform r1t1-8a57; CBFA2T1 isoform r1t1-8a58; CBFA2T1 isoform r1t1-8a59; CBFA2T1 isoform r1t1-8a60; Cbfa2t1h; CDR; core-binding factor, runt domain, alpha subunit 2, translocated to, 1; core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related; cyclin D-related; Cyclin-D-related protein; Eight twenty one protein; ETO; LOC100155449; LOC100354419; MGC2796; Mtg8; MTG8b; myeloid translocation gene on 8q22; Protein CBFA2T1; protein CBFA2T1-like; Protein ETO; Protein MTG8; runt related transcription factor 1; translocated to, 1 (cyclin D related); runt-related transcription factor 1; translocated to, 1 (cyclin D-related); RUNX1 translocation partner 1; RUNX1T1; si:ch211-232j17.1; translocated to, 1; wu:fi14b07; zgc:154044; Zinc finger MYND domain-containing protein 2; ZMYND2

Gene Symbols

RUNX1T1

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Related Products

Img

Fischer Scientific

7188542

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188566

Rat Monoclonal Antibody...

Img

Fischer Scientific

7188566

Rat Monoclonal Antibody...

Img

Fischer Scientific

7188758

Mouse Monoclonal Antibody...

Img

Fischer Scientific

7188759

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188706

Rat Monoclonal Antibody...

Img

Fischer Scientific

7188389

Mouse Monoclonal Antibody...

Img

Fischer Scientific

7188389

Mouse Monoclonal Antibody...

Description

  • RUNX1T1 is a putative zinc finger transcription factor and oncoprotein
  • In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities
  • The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene
  • The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation
  • The protein encoded by this gene is a putative zinc finger transcription factor and oncoprotein
  • In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities
  • The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene
  • The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation
  • Several transcript variants encoding multiple isoforms have been found for this gene.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7188399

Rabbit Polyclonal Antibody...


Antigen:
ETO / RUNX1T1

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q06455

Gene ID (Entrez):
862

Immunogen:
This ETO / RUNX1T1 antibody was raised against a peptide within the internal region of human ETO / RUNX1T1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
RUNX1T1

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
acute myelogenous leukemia 1 translocation 1 protein; acute myelogenous leukemia 1 translocation 1, cyclin-D related; AML1-MTG8; AML1T1; BOS_14107; Cbfa2t1; CBFA2T1 identified gene homolog; CBFA2T1 isoform r1t1-11a61; CBFA2T1 isoform r1t1-11a62; CBFA2T1 isoform r1t1-11a63; CBFA2T1 isoform r1t1-11a64; CBFA2T1 isoform r1t1-11a65; CBFA2T1 isoform r1t1-7a47; CBFA2T1 isoform r1t1-7a48; CBFA2T1 isoform r1t1-7a49; CBFA2T1 isoform r1t1-7a50; CBFA2T1 isoform r1t1-7a51; CBFA2T1 isoform r1t1-7a52; CBFA2T1 isoform r1t1-7d53; CBFA2T1 isoform r1t1-7d54; CBFA2T1 isoform r1t1-7d55; CBFA2T1 isoform r1t1-7d56; CBFA2T1 isoform r1t1-8a57; CBFA2T1 isoform r1t1-8a58; CBFA2T1 isoform r1t1-8a59; CBFA2T1 isoform r1t1-8a60; Cbfa2t1h; CDR; core-binding factor, runt domain, alpha subunit 2, translocated to, 1; core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related; cyclin D-related; Cyclin-D-related protein; Eight twenty one protein; ETO; LOC100155449; LOC100354419; MGC2796; Mtg8; MTG8b; myeloid translocation gene on 8q22; Protein CBFA2T1; protein CBFA2T1-like; Protein ETO; Protein MTG8; runt related transcription factor 1; translocated to, 1 (cyclin D related); runt-related transcription factor 1; translocated to, 1 (cyclin D-related); RUNX1 translocation partner 1; RUNX1T1; si:ch211-232j17.1; translocated to, 1; wu:fi14b07; zgc:154044; Zinc finger MYND domain-containing protein 2; ZMYND2

Gene Symbols:
RUNX1T1

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7188400

Mouse Recombinant Monoclonal Antibo...


Antigen:
HIF-1 alpha

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Bovine, Human, Mouse, Rat

Gene Accession No.:
O35800, Q16665, Q61221, Q9XTA5

Gene ID (Entrez):
15251, 281814, 29560, 3091

Immunogen:
This HIF-1 alpha antibody was raised against a partial protein containing amino acid residues 329-530 of human HIF-1 alpha.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
HIF1A

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
200mM HEPES, 50mM sodium acetate with 100mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
AA959795; ARNT interacting protein; ARNT2; ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; BHLHE78; BOS_11009; Class E basic helix-loop-helix protein 78; HIF1; HIF1 alpha; HIF-1 alpha; hif1a; HIF-1A; hif1a.L; HIF1alpha; hif-1alpha; HIF-1-alpha; HIF1-alpha; HIF1-alpha protein; hypoxia inducible factor 1 alpha; hypoxia inducible factor 1 alpha subunit; hypoxia inducible factor 1 alpha subunit L homeolog; hypoxia inducible factor 1 subunit alpha; hypoxia inducible factor 1 subunit alpha L homeolog; hypoxia inducible factor 1, alpha subunit; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1 alpha; hypoxia-inducible factor 1 alpha isoform I.3; hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) L homeolog; Hypoxia-inducible factor 1-alpha; hypoxia-inducible factor1alpha; Member of PAS protein 1; member of PAS superfamily 1; MOP1; PAS domain-containing protein 8; PASD8; XELAEV_18039792mg; XELAEV_18041137mg; xhif1a

Gene Symbols:
HIF1A

Isotype:
IgG2a

Purification Method:
Metal-chelate chromatography

Product Type:
Antibody

Img

Fischer Scientific

7188402

Rat Monoclonal Antibody...


Antigen:
MyoD

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human, Mouse

Gene Accession No.:
P10085, P15172

Gene ID (Entrez):
17927, 4654

Immunogen:
This MyoD antibody was raised against a recombinant protein corresponding to full-length mouse MyoD.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
MYOD1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
AI503393; BHLHC1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; Myoblast determination protein 1 homolog; MYOD; Myod1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; Myogenic factor 3; PUM

Gene Symbols:
MYOD1

Isotype:
IgG2a

Purification Method:
Protein G

Product Type:
Antibody

Img

Fischer Scientific

7188404

Mouse Recombinant Monoclonal Antibo...


Antigen:
Ubiquitin

Applications:
Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P62987

Gene ID (Entrez):
7311

Immunogen:
This antibody was raised against bovine ubiquitin.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
UBA52

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5

Gene Alias:
60S ribosomal protein L40; BOS_7110; CEP52; D8Ertd21e; Gm1863; HUB L40; HUBCEP52; L40; Large ribosomal subunit protein eL40; MGC127041; RPL40; RPS27A; UBA52; Ubb; UBC; UBCEP2; Ubiquitin; Ubiquitin A-52 residue ribosomal protein fusion product 1; ubiquitin and ribosomal protein L40; ubiquitin carboxyl extension protein 52; ubiquitin/60S ribosomal fusion protein; ubiquitin-52 amino acid fusion protein; Ubiquitin-60S ribosomal protein L40; ubiquitin-CEP52

Gene Symbols:
UBA52

Isotype:
IgG2a

Purification Method:
Protein A

Product Type:
Antibody