7188446

Phospho-RNA pol II CTD (Ser2) Monoclonal Antibody (3E10), Active Motif™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Phospho-RNA pol II CTD (Ser2)

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypept

Gene Symbols

POLA1, POLR2A

Isotype

IgG1

Purification Method

Protein G

Product Type

Antibody

Clone

3E10

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence

Conjugate

Unconjugated

Host Species

Rat

Target Species

Human, Mouse

Gene Accession No.

P08775, P09884, P24928, P33609

Gene ID (Entrez)

18968, 20020, 5422, 5430

Immunogen

This RNA pol II CTD phospho Ser2 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 2.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

POLA1

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Description

  • RNA polymerase II is the enzyme responsible for the synthesis of mRNA and many non-coding RNAs
  • POLR2A encodes RNA polymerase II subunit B1 (RPB1), the largest subunit of RNA polymerase II
  • The C-terminal domain (CTD) of RPB1 contains tandem heptapeptide repeats with the consensus sequence YSPTSPS
  • Phosphorylation and other modifications within this sequence influence the recruitment of factors that regulate the transcription cycle
  • Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the CTD.

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Fischer Scientific

7188446

Rat Monoclonal Antibody...


Antigen:
Phospho-RNA pol II CTD (Ser2)

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypept

Gene Symbols:
POLA1, POLR2A

Isotype:
IgG1

Purification Method:
Protein G

Product Type:
Antibody

Clone:
3E10

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human, Mouse

Gene Accession No.:
P08775, P09884, P24928, P33609

Gene ID (Entrez):
18968, 20020, 5422, 5430

Immunogen:
This RNA pol II CTD phospho Ser2 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 2.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
POLA1

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Fischer Scientific

7188447

Rabbit Polyclonal Antibody...


Antigen:
Histone H3K27me1

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K27; H3.2; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-3A; H3-3B; H3a; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3F1K; H3F2; H3F3; H3F3A; H3F3B; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3k27; H3K27me; H3Lys27me; H3Lys27me1; HIST1H3A; HIST1H3B; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; HIST2H3C; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; Histone 3; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 2, H3a; histone cluster 2, H3c; Histone H3; Histone H3.1; Histone H3.2; Histone H3.3; Histone H3.3C; Histone H3.5; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; Histone H3/m; Histone H3/o; Histone H3K27me1; histone variant H3.5; methyl Histone 3; methyl Histone H3; Methyl-H3 K27; Methyl-H3 Lys27; Methyl-Histone H3 K27; Methyl-Histone H3 Lys27; Mono-methyl H3; Mono-methyl Histone H3; PP781

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Clone:
__

Applications:
Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Immunogen:
This Histone H3 monomethyl Lys27 antibody was raised against a peptide including monomethyl-lysine 27 of human histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3-3A

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7188448

Rat Monoclonal Antibody...


Antigen:
ASH2L

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
ASH 2; ASH2; ash2 (absent, small, or homeotic)-like; ash2 (absent, small, or homeotic)-like (Drosophila); ASH2 LIKE; ASH2 like histone lysine methyltransferase complex subunit; ASH2 like protein; ASH2 like, histone lysine methyltransferase complex subunit; Ash2l; ASH2L1; ASH2L2; ash2-like; ASH2-like protein; BOS_23936; Bre 2; Bre2; LOC100338600; Set1/Ash2 histone methyltransferase complex subunit ASH2

Gene Symbols:
ASH2L

Isotype:
IgG2a

Purification Method:
Protein G

Product Type:
Antibody

Clone:
4C5

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
Q9UBL3

Gene ID (Entrez):
9070

Immunogen:
This antibody was raised against a recombinant protein corresponding to the N-terminal region of human ASH2L.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
ASH2L

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Fischer Scientific

7188449

Rabbit Polyclonal Antibody...


Antigen:
Histone H3R17me2a (asymmetric)

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
Di histone H3/c; dimethyl H3; di-methyl H3; Dimethyl Histone H3; di-methyl histone H3; Di-Methyl-H3 Arg17; Di-Methyl-H3 R17; Di-Methyl-Histone H3 Arg17; Di-Methyl-Histone H3 R17; Di-Methyl-Histone H3.1 Arg17; Di-Methyl-Histone H3.1 R17; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 R17me2a; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3b; H3-53; H3-614; H3a; H3Arg17me2; H3Arg17me2a; H3Arg17me2s; H3b; H3-B; H3c1; H3C10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3B; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3R17; H3R17me2; H3R17me2s; Hist1; Hist1h3a; HIST1H3B; Hist1h3c; HIST1H3D; Hist1h3e; Hist1h3f; Hist1h3g; HIST1H3H; Hist1h3i; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3f; histone cluster 1, H3h; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone gene complex 1; histone H3; Histone H3.1; Histone H3.2; Histone H3.3; Histone H3.3C; Histone H3.5; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; Histone H3/m; Histone H3/o; Histone H3R17; Histone H3R17me2; Histone H3R17me2a; histone variant H3.5; M32461; methyl Histone 3; methyl Histone H3; PP781

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Clone:
__

Applications:
Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Immunogen:
This Histone H3 dimethyl Arg17 asymmetric antibody was raised against a peptide containing dimethyl-Arg17 (asymmetric) of human histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3-3A