7188458

Phospho-RNA pol II CTD (Ser2) Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™

Mouse Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Phospho-RNA pol II CTD (Ser2)

Applications

ChIP sequencing (ChIP-seq), ELISA, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P09884, P24928

Gene ID (Entrez)

5422, 5430

Immunogen

This RNA pol II CTD phospho Ser2 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 2.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

POLR2A

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

200mM HEPES, 50mM sodium acetate with 100mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypept

Gene Symbols

POLA1, POLR2A

Isotype

IgG2a

Purification Method

Metal-chelate chromatography

Product Type

Antibody

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Description

  • RNA polymerase II is the enzyme responsible for the synthesis of mRNA and many non-coding RNAs
  • POLR2A encodes RNA polymerase II subunit B1 (RPB1), the largest subunit of RNA polymerase II
  • The C-terminal domain (CTD) of RPB1 contains tandem heptapeptide repeats with the consensus sequence YSPTSPS
  • Phosphorylation and other modifications within this sequence influence the recruitment of factors that regulate the transcription cycle
  • Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the CTD.

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Show Difference

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Fischer Scientific

7188458

Mouse Recombinant Monoclonal Antibo...


Antigen:
Phospho-RNA pol II CTD (Ser2)

Applications:
ChIP sequencing (ChIP-seq), ELISA, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P09884, P24928

Gene ID (Entrez):
5422, 5430

Immunogen:
This RNA pol II CTD phospho Ser2 antibody was raised against a peptide containing the RNA pol II CTD sequence phosphorylated at serine 2.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
POLR2A

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
200mM HEPES, 50mM sodium acetate with 100mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; POLA1; POLR2; Polr2a; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypept

Gene Symbols:
POLA1, POLR2A

Isotype:
IgG2a

Purification Method:
Metal-chelate chromatography

Product Type:
Antibody

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7188462

Rabbit Polyclonal Antibody...


Antigen:
Ikaros

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
Q03267

Gene ID (Entrez):
22778

Immunogen:
This Ikaros antibody was raised against a recombinant protein corresponding to the N-terminal half of mouse Ikaros.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
IKZF1

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
5832432G11Rik; BOS_3969; CLL-associated antigen KW-6; CVID13; DNA-binding protein Ikaros; hIk-1; hlk-1; Hs.54452; IK1; IKAROS; IKAROS family zinc finger 1; IKAROS family zinc finger 1 (Ikaros); Ikaros family zinc finger protein 1; IKZF1; KAROS family zinc finger 1 (Ikaros); LYF1; LyF-1; Lymphoid transcription factor LyF-1; mKIAA4227; PPP1R92; PRO0758; protein phosphatase 1, regulatory subunit 92; RGD1562979; Zfpn1a1; zinc finger containing transcription factor; zinc finger protein, subfamily 1A, 1 (Ikaros); ZNFN1A1

Gene Symbols:
IKZF1

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

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7188463

Mouse Recombinant Monoclonal Antibo...


Antigen:
SaCas9

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P55211

Gene ID (Entrez):
842

Immunogen:
This antibody was raised against a recombinant protein fragment containing amino acids 1-462 of Staphylococcus aureus Cas9.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
CASP9

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5

Gene Alias:
APAF3; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; cas9; CASP 9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; CRISPR-Cas9; CTD; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3

Gene Symbols:
CASP9

Isotype:
IgG2a

Purification Method:
Protein A

Product Type:
Antibody

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Antigen:
SaCas9

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P55211

Gene ID (Entrez):
842

Immunogen:
This antibody was raised against a recombinant protein fragment containing amino acids 1-462 of Staphylococcus aureus Cas9.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
CASP9

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5

Gene Alias:
APAF3; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; cas9; CASP 9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; CRISPR-Cas9; CTD; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3

Gene Symbols:
CASP9

Isotype:
IgG2a

Purification Method:
Protein A

Product Type:
Antibody