7188480

ASH2L Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

ASH2L

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q9UBL3

Gene ID (Entrez)

9070

Immunogen

This ASH2L antibody was raised against full-length recombinant human ASH2L protein.

Primary or Secondary

Primary

Product Type

Antibody

Concentration

Conc. Not Determined

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias

ASH 2; ASH2; ash2 (absent, small, or homeotic)-like; ash2 (absent, small, or homeotic)-like (Drosophila); ASH2 LIKE; ASH2 like histone lysine methyltransferase complex subunit; ASH2 like protein; ASH2 like, histone lysine methyltransferase complex subunit; Ash2l; ASH2L1; ASH2L2; ash2-like; ASH2-like protein; BOS_23936; Bre 2; Bre2; LOC100338600; Set1/Ash2 histone methyltransferase complex subunit ASH2

Gene Symbols

ASH2L

Isotype

IgG

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

ASH2L

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Description

  • The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator
  • Its predicted molecular weight is 68.7kDa
  • Alternative splicing results in possible isoforms at 60 kDa & 56.5 kDa)
  • Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif
  • Homology to mouse ASH2L is 90%
  • ASH2L is predominantly expressed in adult heart and testis and fetal lung and liver, with barely detectable expression in adult lung, liver, kidney, prostate, and peripheral leukocytes as well as leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami
  • Differentiation inducers (e.g
  • phorbol ester and hemin) cause different expression patterns in these cell lines, suggesting that ASH2L plays a role in hematopoiesis and is associated with particular types of leukemia
  • In addition ASH2L has been suggested to interact with beta-tubulin and beta-catenin.

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Fischer Scientific

7188480

Rabbit Polyclonal Antibody...


Antigen:
ASH2L

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9UBL3

Gene ID (Entrez):
9070

Immunogen:
This ASH2L antibody was raised against full-length recombinant human ASH2L protein.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
ASH 2; ASH2; ash2 (absent, small, or homeotic)-like; ash2 (absent, small, or homeotic)-like (Drosophila); ASH2 LIKE; ASH2 like histone lysine methyltransferase complex subunit; ASH2 like protein; ASH2 like, histone lysine methyltransferase complex subunit; Ash2l; ASH2L1; ASH2L2; ash2-like; ASH2-like protein; BOS_23936; Bre 2; Bre2; LOC100338600; Set1/Ash2 histone methyltransferase complex subunit ASH2

Gene Symbols:
ASH2L

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
ASH2L

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7188481

Mouse Monoclonal Antibody...


Antigen:
beta Tubulin

Applications:
Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P04350, P07437, Q13509, Q13885, Q3ZCM7, Q9BUF5, Q9H4B7

Gene ID (Entrez):
10381, 10382, 203068, 347688, 7280, 81027, 84617

Immunogen:
This beta-tubulin antibody was raised against sarkosyl-resistant filaments fromStrongylocentrotus purpuratus(sea urchin) sperm axonemes.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
2310057H16Rik; 2810484G07Rik; 3200002H15Rik; AA408537; AI325297; AI596182; B130022C14Rik; bA631M21.2; BB220206; beta 5-tubulin; beta Ib tubulin; beta tubulin; beta tubulin 1; beta-4; beta-4 tubulin; beta-4-tubulin; beta-5; beta-5 tubulin; beta5-tubulin; betaIII-tubulin; Beta-tubulin class-III; Beta-tubulin class-V; Beta-tubulin class-VI; Beta-tubulin isotype I; BOS_13459; BOS_17166; BOS_21644; BOS_22279; BOS_7641; c(beta)7 tubulin; CDCBM; CDCBM1; CDCBM5; CDCBM6; CFEOM3; CFEOM3A; CH242-247L10.4; class I beta tubulin; Class I beta-tubulin; class IIa beta-tubulin; class III beta-tubulin; class IVa beta-tubulin; class V beta tubulin; class V beta-tubulin; CSCSC1; dJ40E16.7; dystonia 4, torsion (autosomal dominant); DYT4; FEOM3; HSA10p15 beta-tubulin 4Q; HsT1601; hypothetical protein LOC550458; I79_000194; I79_012097; LOC100347858; LOC100358689; LOC100761889; M(beta)1; M(beta)2; M(beta)3; M(beta)4; M(beta)5; M(beta)6; M40; M40 antibody; Neuron-specific class III beta-tubulin; OK/SW-cl.56; OOMD; OOMD2; RGD1305887; si:ch211-122i22.4; si:ch211-9a18.2; TUBB; tubb beta-5; tubb.L; TUBB1; TUBB2; TUBB2A; tubb2a {ECO:0000250; TUBB2B; TUBB3; TUBB4; TUBB4A; Tubb5; TUBB-5; Tubb6; TUBB8; Tubulin 5 beta; tubulin beta 1 class VI; tubulin beta 2A class IIa; tubulin beta 3 class III; Tubulin beta 4'; tubulin beta 4A class IVa; tubulin beta 6 class V; Tubulin beta 8 class VIII; Tubulin beta chain; tubulin beta class I; tubulin beta class I L homeolog; Tubulin beta class IIa; Tubulin beta class V; tubulin beta MGC4083; tubulin beta-1; Tubulin beta-1 chain; Tubulin beta-2A chain; tubulin beta-2B chain; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-4A chain; Tubulin beta-5 chain; Tubulin beta-6 chain; Tubulin beta-7 chain; Tubulin beta-8 chain; Tubulin beta-III; tubulin, beta 1 class VI; tubulin, beta 1-like; tubulin, beta 2; tubulin, beta 2A; tubulin, beta 2A class IIa; tubulin, beta 2B class IIb; tubulin, beta 3; tubulin, beta 3 class III; tubulin, beta 4; tubulin, beta 4 class IVa; tubulin, beta 4A class IVa; tubulin, beta 5; tubulin, beta 5 class I; tubulin, beta 5-like; tubulin, beta 6 class V; tubulin, beta class I; tubulin, beta family 1; tubulin, beta polypeptide; tubulin, beta polypeptide 2; tubulin, beta, 3; tubulin, beta, 4; tubulin, beta, 5; uncharacterized protein LOC550458; UniProtKB:Q7TMM9}; XELAEV_18039222mg; XLOT; zbetaI; zgc:112515

Gene Symbols:
TUBB, Tubb1, Tubb2a, Tubb3, Tubb4a, Tubb6, TUBB8

Isotype:
IgG1 κ

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Tubb1

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7188482

Rat Monoclonal Antibody...


Antigen:
Phospho-RNA pol II CTD (Tyr1)

Applications:
ChIP sequencing (ChIP-seq), Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P24928

Gene ID (Entrez):
5430

Immunogen:
This antibody was raised against a synthetic peptide containing the RNA Pol II heptad repeat consensus sequence phosphorylated at tyrosine 1.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8

Gene Symbols:
POLR2A

Isotype:
IgG1

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
POLR2A

Img

Fischer Scientific

7188482

Rat Monoclonal Antibody...


Antigen:
Phospho-RNA pol II CTD (Tyr1)

Applications:
ChIP sequencing (ChIP-seq), Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P24928

Gene ID (Entrez):
5430

Immunogen:
This antibody was raised against a synthetic peptide containing the RNA Pol II heptad repeat consensus sequence phosphorylated at tyrosine 1.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8

Gene Symbols:
POLR2A

Isotype:
IgG1

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
POLR2A