7188563

Histone H3K27me2me3 Monoclonal Antibody (7B11), Active Motif™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Histone H3K27me2me3

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

10mM sodium phosphate with 150mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype

IgG

Purification Method

Protein A

Product Type

Antibody

Clone

7B11

Applications

Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Immunogen

This Histone H3 di/trimethyl Lys27 antibody was raised against a peptide including trimethyl-lysine 27 of histone H3.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

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Description

  • Description Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells
  • H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome
  • Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability
  • Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors
  • The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes
  • These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

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Fischer Scientific

7188563

Mouse Monoclonal Antibody...


Antigen:
Histone H3K27me2me3

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
10mM sodium phosphate with 150mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Clone:
7B11

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Immunogen:
This Histone H3 di/trimethyl Lys27 antibody was raised against a peptide including trimethyl-lysine 27 of histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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7188564

Mouse Monoclonal Antibody...


Antigen:
HIPK2

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG

Purification Method:
Protein G

Product Type:
Antibody

Clone:
3E9

Applications:
ChIP Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Immunogen:
This HIPk2 antibody was raised against a recombinant protein including amino acids 898-1051 of mouse HIPk2.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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Antigen:
SMARCA4 / BRG1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG2b

Purification Method:
Protein G

Product Type:
Antibody

Clone:
3G4

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human, Mouse

Immunogen:
This SMARCA4 / BRG1 antibody was raised against a recombinant protein corresponding to amino acids 214-279 of mouse BRG1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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Rat Monoclonal Antibody...


Antigen:
SMARCA4 / BRG1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG2b

Purification Method:
Protein G

Product Type:
Antibody

Clone:
3G4

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human, Mouse

Immunogen:
This SMARCA4 / BRG1 antibody was raised against a recombinant protein corresponding to amino acids 214-279 of mouse BRG1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles