7188753

Histone H3S10ph Monoclonal Antibody (6G8B7), Active Motif™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Histone H3S10ph

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype

IgG2a

Purification Method

Protein G

Product Type

Antibody

Clone

6G8B7

Applications

ELISA, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Rat

Target Species

Human

Immunogen

This antibody was raised against a peptide corresponding to amino acids 1-19 including phospho-serine 10 of human Histone H3.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

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Description

  • Description Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells
  • H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome
  • Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability
  • Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors
  • The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes
  • These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

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Fischer Scientific

7188753

Rat Monoclonal Antibody...


Antigen:
Histone H3S10ph

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype:
IgG2a

Purification Method:
Protein G

Product Type:
Antibody

Clone:
6G8B7

Applications:
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human

Immunogen:
This antibody was raised against a peptide corresponding to amino acids 1-19 including phospho-serine 10 of human Histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Img

Fischer Scientific

7188754

Mouse Monoclonal Antibody...


Antigen:
Estrogen Receptor beta

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG2a

Purification Method:
Protein G

Product Type:
Antibody

Clone:
CO1531

Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Immunogen:
This Estrogen Receptor beta antibody was raised against a recombinant protein corresponding to amino acids 212-477 of human Estrogen Receptor beta.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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7188755

Rabbit Polyclonal Antibody...


Antigen:
KLF5

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Clone:
__

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Immunogen:
This kLF5 antibody was raised against a peptide derived from the N-terminus of mouse kLF5 (krueppel-like factor 5).

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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Mouse Monoclonal Antibody...


Antigen:
HDAC1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
antibody with 30% glycerol and 0.035% sodium azide; pH

Isotype:
IgG1

Purification Method:
__

Product Type:
Antibody

Clone:
10E2

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse, Rat

Immunogen:
This HDAC1 antibody was raised against a kLH-conjugated peptide corresponding to amino acids 467-482 of human and murine HDAC1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles