7188600

SATB1 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

SATB1

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

Q01826, Q60611

Gene ID (Entrez)

20230, 6304

Immunogen

This SATB1 antibody was raised against a peptide within the N-terminal region of SATB1.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Satb1

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

2610306G12Rik; AW413156; DNA-binding protein SATB1; SATB homeobox 1; Satb1; special AT-rich sequence binding protein 1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA); Special AT-rich sequence-binding protein 1

Gene Symbols

Satb1

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Related Products

Img

Fischer Scientific

7188760

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188760

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188382

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188536

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188708

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188677

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188437

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188437

Rabbit Polyclonal Antibody...

Description

  • SATB1 (DNA-binding protein SATB1) is a crucial silencing factor that contributes to the initiation of X inactiviation mediated by Xist RNA that occurs during embryogenesis and in lymphoma
  • SATB1 binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence, and at nuclear matrix- or scaffold-associated regions
  • It is thought to recognize the sugar-phosphate structure of double-stranded DNA
  • SATB1 is also a transcriptonal repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner by binding to matrix attachment regions of DNA and inducing a local chromatin-loop remodeling
  • SATB1 modulates the genes that are essential in the maturatio of the immune T-cell CD8SP from thymocytes
  • Alu-like motifs and SATB1-binding sites provide an unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery
  • Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL1 and IL2RA in T-cells by binding to the same domain as HDAC1.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7188600

Rabbit Polyclonal Antibody...


Antigen:
SATB1

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q01826, Q60611

Gene ID (Entrez):
20230, 6304

Immunogen:
This SATB1 antibody was raised against a peptide within the N-terminal region of SATB1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Satb1

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
2610306G12Rik; AW413156; DNA-binding protein SATB1; SATB homeobox 1; Satb1; special AT-rich sequence binding protein 1; special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA); Special AT-rich sequence-binding protein 1

Gene Symbols:
Satb1

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7188602

Rabbit Polyclonal Antibody...


Antigen:
MOF / MYST1

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9H7Z6

Gene ID (Entrez):
84148

Immunogen:
This MOF / MYST1 antibody was raised against a peptide within the N-terminal region of human MOF / MYST1 (MYST histone acetyltransferase 1).

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
KAT8

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
2010203C02Rik; 5830450F21Rik; D7Ertd629e; h FLJ14040; Histone acetyltransferase KAT8; histone acetyltransferase MYST1; hMOF; K (lysine) acetyltransferase 8; K(lysine) acetyltransferase 8; Kat8; Lysine acetyltransferase 8; Mof; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST protein 1; MYST1; MYST-1; ortholog of Drosophila males absent on the first (MOF); PP7073; probable histone acetyltransferase MYST1; ZC2HC8

Gene Symbols:
KAT8

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7188603

Rabbit Polyclonal Antibody...


Antigen:
Histone H3K27ac

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Immunogen:
This Histone H3 acetyl Lys27 antibody was raised against a peptide including acetyl-lysine 27 of histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3-3A

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
Acetyl H3; Acetyl Histone H3; Acetyl-H3 K27; Acetyl-H3 Lys27; Acetyl-Histone H3 K27; Acetyl-Histone H3 Lys27; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K27ac; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3c10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3f3b; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3k27; H3Lys27ac; Hist1; Hist1h3a; HIST1H3B; Hist1h3c; HIST1H3D; Hist1h3e; HIST1H3F; HIST1H3G; HIST1H3H; Hist1h3i; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1;

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Img

Fischer Scientific

7188606

Mouse Monoclonal Antibody...


Antigen:
Aiolos

Applications:
ChIP Assay, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Mouse

Gene Accession No.:
O08900

Gene ID (Entrez):
22780

Immunogen:
This Aiolos antibody was raised against the N-terminal half of mouse Aiolos protein.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Ikzf3

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
5830411O07Rik; AIO; AIOLOS; BOS_19124; IKAROS family zinc finger 3; IKAROS family zinc finger 3 (Aiolos); Ikaros family zinc finger protein 3; Ikzf3; LOC100356392; Zfpn1a3; zinc finger DNA binding protein Aiolos; Zinc finger protein Aiolos; zinc finger protein, subfamily 1A, 3 (Aiolos); ZNFN1A3

Gene Symbols:
Ikzf3

Isotype:
IgG

Purification Method:
Protein G

Product Type:
Antibody