7188536
MBD1 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MBD1
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q9UIS9
Gene ID (Entrez)
4152
Immunogen
This MBD1 antibody was raised against a peptide within the C-terminal region of human MBD1.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
MBD1
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
CXXC3; CXXC-type zinc finger protein 3; Mbd1; methyl-CpG binding domain protein 1; methyl-CpG binding domain protein 1 isoform PCM1; Methyl-CpG-binding domain protein 1; Methyl-CpG-binding protein MBD1; PCM1; Protein containing methyl-CpG-binding domain 1; RFT; the regulator of fibroblast growth factor 2 (FGF-2) transcription
Gene Symbols
MBD1
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- Methyl-CpG-binding domain protein 1 (MBD1) is a member of a family of mammalian proteins that specifically bind methylated regions of DNA
- It is a transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides
- Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS)
- MBD1 acts as a transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1
- Isoform 1 and isoform 2 can also repress transcription from unmethylated promoters.
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Antigen: MBD1
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9UIS9
Gene ID (Entrez): 4152
Immunogen: This MBD1 antibody was raised against a peptide within the C-terminal region of human MBD1.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: MBD1
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: CXXC3; CXXC-type zinc finger protein 3; Mbd1; methyl-CpG binding domain protein 1; methyl-CpG binding domain protein 1 isoform PCM1; Methyl-CpG-binding domain protein 1; Methyl-CpG-binding protein MBD1; PCM1; Protein containing methyl-CpG-binding domain 1; RFT; the regulator of fibroblast growth factor 2 (FGF-2) transcription
Gene Symbols: MBD1
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
MBD1
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9UIS9
Gene ID (Entrez):
4152
Immunogen:
This MBD1 antibody was raised against a peptide within the C-terminal region of human MBD1.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
MBD1
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
CXXC3; CXXC-type zinc finger protein 3; Mbd1; methyl-CpG binding domain protein 1; methyl-CpG binding domain protein 1 isoform PCM1; Methyl-CpG-binding domain protein 1; Methyl-CpG-binding protein MBD1; PCM1; Protein containing methyl-CpG-binding domain 1; RFT; the regulator of fibroblast growth factor 2 (FGF-2) transcription
Gene Symbols:
MBD1
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Antigen: SIRT2
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q8IXJ6
Gene ID (Entrez): 22933
Immunogen: This SIRT2 antibody was raised against a synthetic peptide derived from the C-terminal region of human SIRT2.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: SIRT2
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: 5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; SIRT2; sirtuin 2; sirtuin type 2; sirtuin-2
Gene Symbols: SIRT2
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
SIRT2
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q8IXJ6
Gene ID (Entrez):
22933
Immunogen:
This SIRT2 antibody was raised against a synthetic peptide derived from the C-terminal region of human SIRT2.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
SIRT2
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; SIRT2; sirtuin 2; sirtuin type 2; sirtuin-2
Gene Symbols:
SIRT2
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Antigen: RBPJ
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rat
Target Species: Human
Gene Accession No.: Q06330
Gene ID (Entrez): 3516
Immunogen: This antibody was raised against full-length recombinant human RBPJ protein.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: RBPJ
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: AI843960; AOS3; BOS_6494; CBF1; CBF-1; csl; H-2K binding factor-2; IGKJRB; IGKJRB1; Igkrsbp; immunoglobulin kappa J region recombination signal binding protein 1; J kappa-recombination signal-binding protein; KBF2; LOC100346517; Rbpj; RBP-J; RBP-J kappa; RBPJK; RBP-JK; RBPSUH; recombination signal binding protein for immunoglobulin kappa J region; Recombining binding protein suppressor of hairless; recombining binding protein suppressor of hairless-like; Renal carcinoma antigen NY-REN-30; SUH; suppressor of hairless homolog
Gene Symbols: RBPJ
Isotype: IgG2b
Purification Method: Protein G
Product Type: Antibody
Antigen:
RBPJ
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Human
Gene Accession No.:
Q06330
Gene ID (Entrez):
3516
Immunogen:
This antibody was raised against full-length recombinant human RBPJ protein.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
RBPJ
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
AI843960; AOS3; BOS_6494; CBF1; CBF-1; csl; H-2K binding factor-2; IGKJRB; IGKJRB1; Igkrsbp; immunoglobulin kappa J region recombination signal binding protein 1; J kappa-recombination signal-binding protein; KBF2; LOC100346517; Rbpj; RBP-J; RBP-J kappa; RBPJK; RBP-JK; RBPSUH; recombination signal binding protein for immunoglobulin kappa J region; Recombining binding protein suppressor of hairless; recombining binding protein suppressor of hairless-like; Renal carcinoma antigen NY-REN-30; SUH; suppressor of hairless homolog
Gene Symbols:
RBPJ
Isotype:
IgG2b
Purification Method:
Protein G
Product Type:
Antibody
Antigen: MED15
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q96RN5
Gene ID (Entrez): 51586
Immunogen: This antibody was raised against a peptide within the C-terminal region of human MED15.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: MED15
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: A230074L19Rik; Activator-recruited cofactor 105 kDa component; activator-recruited cofactor, 105-kD; ARC105; AW536074; CAG7A; CTG repeat protein 7a; CTG7A; DKFZp686A2214; DKFZp762B1216; FLJ42282; FLJ42935; MED15; Mediator complex subunit 15; Mediator of RNA polymerase II transcription subunit 15; mPcqap; PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein; PC2 glutamine/Q-rich-associated protein; PC2-glutamine-rich-associated protein; Pcqap; Positive cofactor 2 glutamine/Q-rich-associated protein; positive cofactor 2, glutamine/Q-rich-associated protein; positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein; TIG1; TIG-1; TNRC7; TPA inducible gene-1; TPA inducible protein; TPA-inducible gene 1 protein; trinucleotide repeat containing 7; Trinucleotide repeat-containing gene 7 protein
Gene Symbols: MED15
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
MED15
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q96RN5
Gene ID (Entrez):
51586
Immunogen:
This antibody was raised against a peptide within the C-terminal region of human MED15.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
MED15
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
A230074L19Rik; Activator-recruited cofactor 105 kDa component; activator-recruited cofactor, 105-kD; ARC105; AW536074; CAG7A; CTG repeat protein 7a; CTG7A; DKFZp686A2214; DKFZp762B1216; FLJ42282; FLJ42935; MED15; Mediator complex subunit 15; Mediator of RNA polymerase II transcription subunit 15; mPcqap; PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein; PC2 glutamine/Q-rich-associated protein; PC2-glutamine-rich-associated protein; Pcqap; Positive cofactor 2 glutamine/Q-rich-associated protein; positive cofactor 2, glutamine/Q-rich-associated protein; positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein; TIG1; TIG-1; TNRC7; TPA inducible gene-1; TPA inducible protein; TPA-inducible gene 1 protein; trinucleotide repeat containing 7; Trinucleotide repeat-containing gene 7 protein
Gene Symbols:
MED15
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody