7188538

SIRT2 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

SIRT2

Applications

Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q8IXJ6

Gene ID (Entrez)

22933

Immunogen

This SIRT2 antibody was raised against a synthetic peptide derived from the C-terminal region of human SIRT2.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

SIRT2

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; SIRT2; sirtuin 2; sirtuin type 2; sirtuin-2

Gene Symbols

SIRT2

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair
  • It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells
  • SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise
  • SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.

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Fischer Scientific

7188538

Rabbit Polyclonal Antibody...


Antigen:
SIRT2

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q8IXJ6

Gene ID (Entrez):
22933

Immunogen:
This SIRT2 antibody was raised against a synthetic peptide derived from the C-terminal region of human SIRT2.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
SIRT2

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; SIRT2; sirtuin 2; sirtuin type 2; sirtuin-2

Gene Symbols:
SIRT2

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

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7188540

Rat Monoclonal Antibody...


Antigen:
RBPJ

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
Q06330

Gene ID (Entrez):
3516

Immunogen:
This antibody was raised against full-length recombinant human RBPJ protein.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
RBPJ

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
AI843960; AOS3; BOS_6494; CBF1; CBF-1; csl; H-2K binding factor-2; IGKJRB; IGKJRB1; Igkrsbp; immunoglobulin kappa J region recombination signal binding protein 1; J kappa-recombination signal-binding protein; KBF2; LOC100346517; Rbpj; RBP-J; RBP-J kappa; RBPJK; RBP-JK; RBPSUH; recombination signal binding protein for immunoglobulin kappa J region; Recombining binding protein suppressor of hairless; recombining binding protein suppressor of hairless-like; Renal carcinoma antigen NY-REN-30; SUH; suppressor of hairless homolog

Gene Symbols:
RBPJ

Isotype:
IgG2b

Purification Method:
Protein G

Product Type:
Antibody

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Fischer Scientific

7188542

Rabbit Polyclonal Antibody...


Antigen:
MED15

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q96RN5

Gene ID (Entrez):
51586

Immunogen:
This antibody was raised against a peptide within the C-terminal region of human MED15.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
MED15

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
A230074L19Rik; Activator-recruited cofactor 105 kDa component; activator-recruited cofactor, 105-kD; ARC105; AW536074; CAG7A; CTG repeat protein 7a; CTG7A; DKFZp686A2214; DKFZp762B1216; FLJ42282; FLJ42935; MED15; Mediator complex subunit 15; Mediator of RNA polymerase II transcription subunit 15; mPcqap; PC2 (positive cofactor 2, multiprotein complex) glutamine/Q-rich-associated protein; PC2 glutamine/Q-rich-associated protein; PC2-glutamine-rich-associated protein; Pcqap; Positive cofactor 2 glutamine/Q-rich-associated protein; positive cofactor 2, glutamine/Q-rich-associated protein; positive cofactor 2, multiprotein complex, glutamine/Q-rich-associated protein; TIG1; TIG-1; TNRC7; TPA inducible gene-1; TPA inducible protein; TPA-inducible gene 1 protein; trinucleotide repeat containing 7; Trinucleotide repeat-containing gene 7 protein

Gene Symbols:
MED15

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

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7188543

Rabbit Polyclonal Antibody...


Antigen:
PITX2

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q99697

Gene ID (Entrez):
5308

Immunogen:
This PITX2 antibody was raised against a peptide within the N-terminal region of human PITX2.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
PITX2

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
9430085M16Rik; all1-responsive gene 1; ALL1-responsive protein ARP1; ARP1; BOS_6374; Brx1; BRX1 homeoprotein; Brx1b; Homeobox protein PITX2; homeodomain transcription factor 2; IDG2; IGDS; IGDS2; IHG2; IRID2; Munc30; Orthodenticle-like homeobox 2; Otlx2; paired like homeodomain 2; paired-like homeodomain 1; paired-like homeodomain 2; paired-like homeodomain transcription factor 1; Paired-like homeodomain transcription factor 2; Paired-like homeodomain transcription factor Munc 30; Pituitary homeobox 2; PITX1; PITX2; Pitx-2; Pitx2c; Ptx2; RGS; RIEG; RIEG bicoid-related homeobox transcription factor; rieg bicoid-related homeobox transcription factor 1; RIEG1; rPtx2; RS; S a 1 glycoprotein; S a1glycoprotein; S alpha 1 glycoprotein; S a 1 glycoprotein; S a1glycoprotein; Solurshin

Gene Symbols:
PITX2

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody