7188523
HIRA Monoclonal Antibody (WC15), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
HIRA
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1
Gene Symbols
HIRA
Isotype
IgG
Purification Method
Protein G
Product Type
Antibody
Clone
WC15
Applications
Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Mouse
Gene Accession No.
P54198, Q61666
Gene ID (Entrez)
15260, 7290
Immunogen
This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
HIRA
Related Products
Description
- HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes
- Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochromatin
- It plays an important role in the formation of the senescence-associated heterochromatin foci
- These foci likely mediate the irreversible cell cycle changes that occur in senescent cells
- It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.
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Antigen: HIRA
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1
Gene Symbols: HIRA
Isotype: IgG
Purification Method: Protein G
Product Type: Antibody
Clone: WC15
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse
Gene Accession No.: P54198, Q61666
Gene ID (Entrez): 15260, 7290
Immunogen: This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: HIRA
Antigen:
HIRA
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1
Gene Symbols:
HIRA
Isotype:
IgG
Purification Method:
Protein G
Product Type:
Antibody
Clone:
WC15
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Accession No.:
P54198, Q61666
Gene ID (Entrez):
15260, 7290
Immunogen:
This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
HIRA
Antigen: CDKN2A
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); Cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; HGNC:1787; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; isoforms 1/2/3; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; P14 P16; p14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; P16ink4a; p16-INK4a; P19; P19 TP16; p19; p19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF
Gene Symbols: CDKN2A
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P42771, Q8N726
Gene ID (Entrez): 1029
Immunogen: This antibody was raised against a peptide within the N-terminal region of the p16/INk4a isoform of human CDkN2A.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: CDKN2A
Antigen:
CDKN2A
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
Alternative reading frame; ARF; ARF-INK4a; CDK4 inhibitor p16-INK4; CDK4I; CDKN2; CDKN2A; cdkn2a {ECO:0000312; cell cycle inhibitor; cell cycle negative regulator beta; cell cycle regulator; CMM2; cyclin dependent kinase inhibitor 2A; Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4); Cyclin-dependent kinase 4 inhibitor A; Cyclin-dependent kinase inhibitor 2A; cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4); cyclin-dependent kinase inhibitor 2a p16Ink4a; cyclin-dependent kinase inhibitor 2a p19Arf; cyclin-dependent kinase inhibitor 2A, isoform 1; cyclin-dependent kinase inhibitor 2A, isoform 2; cyclin-dependent kinase inhibitor 2A, isoform 3; cyclin-dependent kinase inhibitor 2A, isoforms 1/2; cyclin-dependent kinase inhibitor protein; EMBL:AAL76336.1, ECO:0000312; EMBL:AAL76338.1, ECO:0000312; HGNC:1787; inhibits CDK4; INK4; INK4A; Ink4a/Arf; INK4a-ARF; isoforms 1/2/3; mitochondrial smARF; MLM; MTS1; MTS-1; Multiple tumor suppressor 1; P14; P14 P16; p14ARF; p16; p16(INK4a); p16Cdkn2a; P16INK4; p16-INK4; P16ink4a; p16-INK4a; P19; P19 TP16; p19; p19ARF; Pctr1; RGD:2323}; TP16; Tumor suppressor ARF
Gene Symbols:
CDKN2A
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P42771, Q8N726
Gene ID (Entrez):
1029
Immunogen:
This antibody was raised against a peptide within the N-terminal region of the p16/INk4a isoform of human CDkN2A.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
CDKN2A
Antigen: SRF
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: AW049942; AW240594; BOS_21550; c-fos serum response element-binding transcription factor; LOC100354695; MCM1; minichromosome maintenance 1 homolog; OTTHUMP00000039820; RGD1559787; Serum response factor; serum response factor (c-fos serum response element-binding transcription factor); Srf
Gene Symbols: SRF
Isotype: IgG2a
Purification Method: Protein G
Product Type: Antibody
Clone: 2C5
Applications: ChIP Assay, ChIP sequencing (ChIP-seq)
Conjugate: Unconjugated
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P11831, Q9JM73
Gene ID (Entrez): 20807, 6722
Immunogen: This antibody was raised against a full-length protein corresponding to mouse SRF.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: SRF
Antigen:
SRF
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
AW049942; AW240594; BOS_21550; c-fos serum response element-binding transcription factor; LOC100354695; MCM1; minichromosome maintenance 1 homolog; OTTHUMP00000039820; RGD1559787; Serum response factor; serum response factor (c-fos serum response element-binding transcription factor); Srf
Gene Symbols:
SRF
Isotype:
IgG2a
Purification Method:
Protein G
Product Type:
Antibody
Clone:
2C5
Applications:
ChIP Assay, ChIP sequencing (ChIP-seq)
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P11831, Q9JM73
Gene ID (Entrez):
20807, 6722
Immunogen:
This antibody was raised against a full-length protein corresponding to mouse SRF.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
SRF
Antigen: SRF
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: AW049942; AW240594; BOS_21550; c-fos serum response element-binding transcription factor; LOC100354695; MCM1; minichromosome maintenance 1 homolog; OTTHUMP00000039820; RGD1559787; Serum response factor; serum response factor (c-fos serum response element-binding transcription factor); Srf
Gene Symbols: SRF
Isotype: IgG2a
Purification Method: Protein G
Product Type: Antibody
Clone: 2C5
Applications: ChIP Assay, ChIP sequencing (ChIP-seq)
Conjugate: Unconjugated
Host Species: Rat
Target Species: Human, Mouse
Gene Accession No.: P11831, Q9JM73
Gene ID (Entrez): 20807, 6722
Immunogen: This antibody was raised against a full-length protein corresponding to mouse SRF.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: SRF
Antigen:
SRF
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
AW049942; AW240594; BOS_21550; c-fos serum response element-binding transcription factor; LOC100354695; MCM1; minichromosome maintenance 1 homolog; OTTHUMP00000039820; RGD1559787; Serum response factor; serum response factor (c-fos serum response element-binding transcription factor); Srf
Gene Symbols:
SRF
Isotype:
IgG2a
Purification Method:
Protein G
Product Type:
Antibody
Clone:
2C5
Applications:
ChIP Assay, ChIP sequencing (ChIP-seq)
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Human, Mouse
Gene Accession No.:
P11831, Q9JM73
Gene ID (Entrez):
20807, 6722
Immunogen:
This antibody was raised against a full-length protein corresponding to mouse SRF.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
SRF