7188728

Phc1 Monoclonal Antibody (6-1-3), Active Motif™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phc1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

AW557034; BOS_5916; DKFZp686A1782; early development regulator 1 (homolog of polyhomeotic 1); early development regulator1 (homolog of polyhomeotic 1); Early development regulatory protein 1; Edr; Edr1; hPH1; LOC100347568; MCPH11; mPH1; PH1; PHC1; polyhomeotic 1-like; polyhomeotic homolog 1; polyhomeotic homolog 1 (Drosophila); polyhomeotic-like 1; polyhomeotic-like 1 (Drosophila); Polyhomeotic-like protein 1; Rae28; RAE-28

Gene Symbols

PHC1

Isotype

IgG

Purification Method

Protein G

Product Type

Antibody

Clone

6-1-3

Applications

Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Mouse

Gene Accession No.

P78364, Q64028

Gene ID (Entrez)

13619, 1911

Immunogen

This Phc1 antibody was raised against a recombinant mouse Phc1 protein fragment.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

PHC1

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Description

  • Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development
  • PHC1 (polyhomeotic homolog 1), also known as EDR1, HPH1 or RAE28, is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex
  • Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A
  • Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others
  • Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain
  • PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

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Fischer Scientific

7188728

Mouse Monoclonal Antibody...


Antigen:
Phc1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
AW557034; BOS_5916; DKFZp686A1782; early development regulator 1 (homolog of polyhomeotic 1); early development regulator1 (homolog of polyhomeotic 1); Early development regulatory protein 1; Edr; Edr1; hPH1; LOC100347568; MCPH11; mPH1; PH1; PHC1; polyhomeotic 1-like; polyhomeotic homolog 1; polyhomeotic homolog 1 (Drosophila); polyhomeotic-like 1; polyhomeotic-like 1 (Drosophila); Polyhomeotic-like protein 1; Rae28; RAE-28

Gene Symbols:
PHC1

Isotype:
IgG

Purification Method:
Protein G

Product Type:
Antibody

Clone:
6-1-3

Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
P78364, Q64028

Gene ID (Entrez):
13619, 1911

Immunogen:
This Phc1 antibody was raised against a recombinant mouse Phc1 protein fragment.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
PHC1

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7188733

Mouse Monoclonal Antibody...


Antigen:
MITF

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
BCC2; BHLHE32; black eyed white; BOS_20839; Bw; Class E basic helix-loop-helix protein 32; CMM8; Gsfbcc2; melanocyte inducing transcription factor; melanogenesis associated transcription factor; Mi; microphtalmia-associated transcription factor; microphthalmia transcription factor; Microphthalmia-associated transcription factor; microphthalmia-associated transcription factor A; microphthalmia-associated transcription factor isoform H protein; microphthalmia-associated transcription factor Trnc-1; microphthalmia-associated transcription factor Trnc-2; microphthalmia-associated transcription factor variant 1; microphthalmia-associated transcription factor variant 2; microphthalmia-associated transcription factor variant 3; microphthalmia-associated transcription factor variant MITF-M(+); MITF; MITF-H; MITF-M; transcription factor, isoform 7; Vit; Vitiligo; Wh; WS2; WS2A

Gene Symbols:
MITF

Isotype:
IgG1

Purification Method:
Protein G

Product Type:
Antibody

Clone:
C5.D5

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq)

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
O75030

Gene ID (Entrez):
4286

Immunogen:
This MITF antibody was raised against an N-terminal fragment of human MITF.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
MITF

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7188734

Mouse Recombinant Monoclonal Antibo...


Antigen:
Histone H3K36me3

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5

Gene Alias:
H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K36; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3f3b; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K36; H3Lys36me3; Hist1; HIST1H3A; Hist1h3b; Hist1h3c; HIST1H3D; HIST1H3E; HIST1H3F; Hist1h3g; Hist1h3h; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3a; histone 1, H3b; histone 1, H3f; hist

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Isotype:
IgG2a

Purification Method:
Protein A

Product Type:
Antibody

Clone:
__

Applications:
ChIP sequencing (ChIP-seq), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Immunogen:
This antibody was raised against a peptide containing trimethly-lysine 36 of histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3-3A

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7188737

Rabbit Polyclonal Antibody...


Antigen:
Histone H4K12ac

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
acetyl Histone H4; Acetyl-H4 K12; Acetyl-H4 Lys12; Acetyl-Histone H4 K12; Acetyl-Histone H4 Lys12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K12ac; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4c11; H4c12; H4C13; H4C14; H4C15; H4C2; H4c3; H4C4; H4C5; H4C6; H4C8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K12; H4K12a; H4Lys12ac; H4M; HIST1H4; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; Hist1h4i; HIST1H4J; Hist1h4k; HIST1H4L; Hist1h4m; HIST2H4; HIST2H4A; HIST2H4B; HIST4H4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster

Gene Symbols:
H4-16, H4C1, H4C14, H4C2, H4C5, H4C9

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Clone:
__

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Yeast

Gene Accession No.:
P62805, P62806

Gene ID (Entrez):
121504, 319158, 326619, 326620, 8294, 8359, 8366, 8367, 8370, 97122

Immunogen:
This Histone H4 acetyl Lys12 antibody was raised against a peptide including acetyl-lysine 12 of histone H4.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H4C1