7188613

5-methylcytosine Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™

Mouse Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

5-methylcytosine

Applications

Dot Blot

Conjugate

Unconjugated

Host Species

Mouse

Formulation

140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5

Immunogen

This antibody was raised against 5-methylcytosine conjugated to kLH.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Gene Alias

5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3

Isotype

IgG2a

Purification Method

Protein A

Product Type

Antibody

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Description

  • Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription
  • It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated
  • An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes
  • Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.

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Img

Fischer Scientific

7188613

Mouse Recombinant Monoclonal Antibo...


Antigen:
5-methylcytosine

Applications:
Dot Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Formulation:
140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5

Immunogen:
This antibody was raised against 5-methylcytosine conjugated to kLH.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Gene Alias:
5mc; 5-mC; 5-meC; 5-Methyl-cytosine; C5H7NO3

Isotype:
IgG2a

Purification Method:
Protein A

Product Type:
Antibody

Img

Fischer Scientific

7188614

Rabbit Polyclonal Antibody...


Antigen:
Histone H3K37ac

Applications:
Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Immunogen:
This antibody was raised against a synthetic peptide containing acetyl-lysine 37 of human Histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Gene Alias:
__

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7188614

Rabbit Polyclonal Antibody...


Antigen:
Histone H3K37ac

Applications:
Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Immunogen:
This antibody was raised against a synthetic peptide containing acetyl-lysine 37 of human Histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Gene Alias:
__

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Img

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7188616

Rabbit Polyclonal Antibody...


Antigen:
Geminin

Applications:
Immunocytochemistry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Rabbit

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Immunogen:
This Geminin antibody was raised against full-length recombinant human Geminin protein.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Gene Alias:
AW546347; Gem; Geminin; Geminin GMNN; geminin, DNA replication inhibitor; Gmnn; MGORS6; OTTHUMP00000039393; RP3 369A17.3

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody