7188576
3-Methylcytosine (3-mC) Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
3-Methylcytosine (3-mC)
Applications
Dot Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Alias
3mc; 3-mC; 3-meC; 3-Methyl-cytosine; C5H7NO3
Isotype
IgG
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Concentration
Conc. Not Determined
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
whole serum with 30% glycerol and 0.035% sodium azide; pH
Immunogen
This 3-methylcytosine antibody was raised against 3-methylcytidine conjugated to kLH and recognizes 3-methylcytosine .
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- 3-methylcytosine arises by erroneous methylation of DNA through spontaneous exposure to endogenous S-adenosyl methionine (SAM)
- Since the N3-position in cytosine is protected in double stranded DNA, this phenomenon mainly occurs in single stranded DNA
- The resulting 3-mC is toxic and mutagenic and increased levels of 3-mC seem to impair cell proliferation
- Therefore, it has to be repaired by the cell
- This is established by oxidative demethylation, which is catalyzed by the AlkB protein.
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Antigen: 3-Methylcytosine (3-mC)
Applications: Dot Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Alias: 3mc; 3-mC; 3-meC; 3-Methyl-cytosine; C5H7NO3
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Concentration: Conc. Not Determined
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Immunogen: This 3-methylcytosine antibody was raised against 3-methylcytidine conjugated to kLH and recognizes 3-methylcytosine .
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
3-Methylcytosine (3-mC)
Applications:
Dot Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Alias:
3mc; 3-mC; 3-meC; 3-Methyl-cytosine; C5H7NO3
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Concentration:
Conc. Not Determined
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Immunogen:
This 3-methylcytosine antibody was raised against 3-methylcytidine conjugated to kLH and recognizes 3-methylcytosine .
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: 5-Carboxylcytosine (5-caC)
Applications: Dot Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: __
Gene Alias: __
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen: This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
5-Carboxylcytosine (5-caC)
Applications:
Dot Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
__
Gene Alias:
__
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen:
This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: ZEB1
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Alias: [delta]EF1; 3110032K11Rik; AREB6; BOS_12951; BZP; Delta EF1; delta-crystallin enhancer binding factor 1; DELTAEF1; DELTA-EF1; FECD6; MEB1; MGC133261; Negative regulator of IL2; Nil2; NIL2A; NIL-2A; NIL-2-A; NIL-2-A zinc finger protein; OTTHUMP00000019405; posterior polymorphous corneal dystrophy 3; PPCD3; RP11-472N13.4; Tcf18; Tcf8; TCF-8; Transcription factor 8; transcription factor 8 (represses interleukin 2 expression); Tw; twirler; ZEB; Zeb1; Zfhep; Zfhx1a; Zfx1a; Zfx1ha; zinc finger E-box binding homeobox 1; Zinc finger E-box-binding homeobox 1; Zinc finger homeobox protein 1a; Zinc finger homeodomain enhancer-binding protein
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen: This ZEB1 antibody was raised against a peptide derived from the N-terminal region of human ZEB1.
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
ZEB1
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Alias:
[delta]EF1; 3110032K11Rik; AREB6; BOS_12951; BZP; Delta EF1; delta-crystallin enhancer binding factor 1; DELTAEF1; DELTA-EF1; FECD6; MEB1; MGC133261; Negative regulator of IL2; Nil2; NIL2A; NIL-2A; NIL-2-A; NIL-2-A zinc finger protein; OTTHUMP00000019405; posterior polymorphous corneal dystrophy 3; PPCD3; RP11-472N13.4; Tcf18; Tcf8; TCF-8; Transcription factor 8; transcription factor 8 (represses interleukin 2 expression); Tw; twirler; ZEB; Zeb1; Zfhep; Zfhx1a; Zfx1a; Zfx1ha; zinc finger E-box binding homeobox 1; Zinc finger E-box-binding homeobox 1; Zinc finger homeobox protein 1a; Zinc finger homeodomain enhancer-binding protein
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen:
This ZEB1 antibody was raised against a peptide derived from the N-terminal region of human ZEB1.
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Histone H2A.XY142ph
Applications: Dot Blot, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Alias: AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2a.x; H2a/x; h2afx; H2AX; H2AX histone; Hist5-2ax; histone 5 protein 2ax; Histone H2A.X; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen: This antibody was raised against a peptide containing phospho-tyrosine 142 of human histone H2A.X.
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Histone H2A.XY142ph
Applications:
Dot Blot, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2a.x; H2a/x; h2afx; H2AX; H2AX histone; Hist5-2ax; histone 5 protein 2ax; Histone H2A.X; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Immunogen:
This antibody was raised against a peptide containing phospho-tyrosine 142 of human histone H2A.X.
Primary or Secondary:
Primary
Product Type:
Antibody