7188652

5-Carboxylcytosine (5-caC) Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

5-Carboxylcytosine (5-caC)

Applications

Dot Blot

Conjugate

Unconjugated

Host Species

Rabbit

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype

IgG

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Concentration

Conc. Not Determined

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Immunogen

This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.

Primary or Secondary

Primary

Product Type

Antibody

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Description

  • 5-carboxylcytosine is the final oxidized derivative of 5-methylcytosine, a type of DNA methylation
  • 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine
  • These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family
  • 5-carboxylcytosine has been shown to cause reduced fidelity of RNA Polymerase II
  • Decreased levels of 5-hydroxymethylcytosine has been found in some cancers.

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Img

Fischer Scientific

7188652

Rabbit Polyclonal Antibody...


Antigen:
5-Carboxylcytosine (5-caC)

Applications:
Dot Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Immunogen:
This 5-Carboxylcytosine antibody was raised against 5-carboxylcytidine conjugated to kLH and recognizes 5-carboxylcytosine.

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7188654

Rabbit Polyclonal Antibody...


Antigen:
PRMT6

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Immunogen:
This PRMT6 antibody was raised against a peptide corresponding to amino acids within the N-terminal region of PRMT6.

Primary or Secondary:
Primary

Product Type:
Antibody

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Fischer Scientific

7188656

Rabbit Polyclonal Antibody...


Antigen:
ATF1

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Immunogen:
This antibody was raised against a peptide within the C-terminal region of human ATF1.

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7188657

Rabbit Polyclonal Antibody...


Antigen:
Histone H2A.Z

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Immunogen:
This Histone H2A.Z antibody was raised against a peptide derived from the C-terminus of human histone H2A.Z.

Primary or Secondary:
Primary

Product Type:
Antibody