7188621

Histone H3R17me2aK18ac Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Histone H3R17me2aK18ac

Applications

ChIP Assay, Dot Blot, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P84244

Gene Symbols

H3F3A, H3F3B

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene ID (Entrez)

15078, 15081

Immunogen

This antibody was raised against a synthetic peptide containing asymmetric dimethyl arginine 17 and acetyl lysine 18 of human Histone H3.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

H3F3B

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Description

  • Description Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells
  • H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome
  • Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability
  • Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors
  • The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes
  • These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

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Img

Fischer Scientific

7188621

Rabbit Polyclonal Antibody...


Antigen:
Histone H3R17me2aK18ac

Applications:
ChIP Assay, Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P84244

Gene Symbols:
H3F3A, H3F3B

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene ID (Entrez):
15078, 15081

Immunogen:
This antibody was raised against a synthetic peptide containing asymmetric dimethyl arginine 17 and acetyl lysine 18 of human Histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3F3B

Img

Fischer Scientific

7188625

Mouse Monoclonal Antibody...


Antigen:
SREBP-2

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q12772

Gene Symbols:
SREBF2

Isotype:
IgG

Purification Method:
Protein G

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene ID (Entrez):
6721

Immunogen:
This SREBP-2 antibody was raised against a recombinant protein corresponding to amino acids 833-1141 of human SREBP-2.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
SREBF2

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7188626

Rat Monoclonal Antibody...


Antigen:
DNMT3B

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
Q9UBC3

Gene Symbols:
Dnmt3b

Isotype:
IgG2b

Purification Method:
Protein G

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene ID (Entrez):
1789

Immunogen:
This antibody was raised against a peptide corresponding to amino acid residue(s) 383-396 of human DNMT3b.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Dnmt3b

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7188627

Mouse Monoclonal Antibody...


Antigen:
RNA pol II

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
C. elegans, Human, Mouse, Rat, Yeast

Gene Accession No.:
P08775, P21951, P24928

Gene Symbols:
POL2, POLR2A

Isotype:
IgG1

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% gelatin and 0.01% thimerosal, 0.1% sodium azide; pH 7.5

Gene ID (Entrez):
20020, 363633, 5430, 855459

Immunogen:
This RNA pol II antibody was raised against a synthetic peptide YSPTSpPS corresponding to human RNA pol II. It recognizes both the phosphorylated and unphosphorylated forms of the largest subunit of RNA pol II.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
POLR2A