7188626
DNMT3B Monoclonal Antibody (2C1), Active Motif™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
DNMT3B
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase 3B; DNA methyltransferase HsaIIIB; DNA methyltransferase MmuIIIB; DNA MTase HsaIIIB; DNA MTase MmuIIIB; Dnmt3; DNMT3B; ICF; ICF1; M.HsaIIIB; m.MmuIIIB; MGC1090; MmuIIIB
Gene Symbols
Dnmt3b
Isotype
IgG2b
Purification Method
Protein G
Product Type
Antibody
Clone
2C1
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rat
Target Species
Human
Gene Accession No.
Q9UBC3
Gene ID (Entrez)
1789
Immunogen
This antibody was raised against a peptide corresponding to amino acid residue(s) 383-396 of human DNMT3b.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Dnmt3b
Related Products
Description
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation
- Studies in mice have demonstrated that DNA methylation is required for mammalian development
- This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation
- The protein localizes primarily to the nucleus and its expression is developmentally regulated
- Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome
- Six alternatively spliced transcript variants have been described
- The full length sequences of variants 4 and 5 have not been determined.
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Antigen: DNMT3B
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase 3B; DNA methyltransferase HsaIIIB; DNA methyltransferase MmuIIIB; DNA MTase HsaIIIB; DNA MTase MmuIIIB; Dnmt3; DNMT3B; ICF; ICF1; M.HsaIIIB; m.MmuIIIB; MGC1090; MmuIIIB
Gene Symbols: Dnmt3b
Isotype: IgG2b
Purification Method: Protein G
Product Type: Antibody
Clone: 2C1
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rat
Target Species: Human
Gene Accession No.: Q9UBC3
Gene ID (Entrez): 1789
Immunogen: This antibody was raised against a peptide corresponding to amino acid residue(s) 383-396 of human DNMT3b.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Dnmt3b
Antigen:
DNMT3B
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
DNA (cytosine-5-)-methyltransferase 3 beta; DNA (cytosine-5)-methyltransferase 3B; DNA methyltransferase 3 beta; DNA methyltransferase 3B; DNA methyltransferase HsaIIIB; DNA methyltransferase MmuIIIB; DNA MTase HsaIIIB; DNA MTase MmuIIIB; Dnmt3; DNMT3B; ICF; ICF1; M.HsaIIIB; m.MmuIIIB; MGC1090; MmuIIIB
Gene Symbols:
Dnmt3b
Isotype:
IgG2b
Purification Method:
Protein G
Product Type:
Antibody
Clone:
2C1
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Human
Gene Accession No.:
Q9UBC3
Gene ID (Entrez):
1789
Immunogen:
This antibody was raised against a peptide corresponding to amino acid residue(s) 383-396 of human DNMT3b.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Dnmt3b
Antigen: RNA pol II
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% gelatin and 0.01% thimerosal, 0.1% sodium azide; pH 7.5
Gene Alias: 220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Gene Symbols: POL2, POLR2A
Isotype: IgG1
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: 4H8
Applications: ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: C. elegans, Human, Mouse, Rat, Yeast
Gene Accession No.: P08775, P21951, P24928
Gene ID (Entrez): 20020, 363633, 5430, 855459
Immunogen: This RNA pol II antibody was raised against a synthetic peptide YSPTSpPS corresponding to human RNA pol II. It recognizes both the phosphorylated and unphosphorylated forms of the largest subunit of RNA pol II.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: POLR2A
Antigen:
RNA pol II
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% gelatin and 0.01% thimerosal, 0.1% sodium azide; pH 7.5
Gene Alias:
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Gene Symbols:
POL2, POLR2A
Isotype:
IgG1
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
4H8
Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
C. elegans, Human, Mouse, Rat, Yeast
Gene Accession No.:
P08775, P21951, P24928
Gene ID (Entrez):
20020, 363633, 5430, 855459
Immunogen:
This RNA pol II antibody was raised against a synthetic peptide YSPTSpPS corresponding to human RNA pol II. It recognizes both the phosphorylated and unphosphorylated forms of the largest subunit of RNA pol II.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
POLR2A
Antigen: RNA pol II
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% gelatin and 0.01% thimerosal, 0.1% sodium azide; pH 7.5
Gene Alias: 220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Gene Symbols: POL2, POLR2A
Isotype: IgG1
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: 4H8
Applications: ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: C. elegans, Human, Mouse, Rat, Yeast
Gene Accession No.: P08775, P21951, P24928
Gene ID (Entrez): 20020, 363633, 5430, 855459
Immunogen: This RNA pol II antibody was raised against a synthetic peptide YSPTSpPS corresponding to human RNA pol II. It recognizes both the phosphorylated and unphosphorylated forms of the largest subunit of RNA pol II.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: POLR2A
Antigen:
RNA pol II
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% gelatin and 0.01% thimerosal, 0.1% sodium azide; pH 7.5
Gene Alias:
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Gene Symbols:
POL2, POLR2A
Isotype:
IgG1
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
4H8
Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
C. elegans, Human, Mouse, Rat, Yeast
Gene Accession No.:
P08775, P21951, P24928
Gene ID (Entrez):
20020, 363633, 5430, 855459
Immunogen:
This RNA pol II antibody was raised against a synthetic peptide YSPTSpPS corresponding to human RNA pol II. It recognizes both the phosphorylated and unphosphorylated forms of the largest subunit of RNA pol II.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
POLR2A
Antigen: Histone H3K27me3
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: CG31613; CG31613 gene product from transcript CG31613-RA; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3 K27; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3c10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3f; H3-F; H3F1K; H3F2; H3F3; h3f3a; H3F3B; h3f3b.1; h3f3c; h3f3d; H3FA; H3FB; H3FC HIST1H3C; H3F
Gene Symbols: H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7
Isotype: IgG
Purification Method: Protein A
Product Type: Antibody
Clone: __
Applications: ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P02301, P68431, P68433, P84228, P84243, Q6NXT2, Q71DI3
Gene ID (Entrez): 126961, 260423, 3020, 3021, 319150, 319152, 333932, 360198, 440093, 625328, 8350, 8357, 8358, 8968, 97114
Immunogen: This Histone H3 trimethyl Lys27 antibody was raised against a peptide including trimethyl-lysine 27 of histone H3. testing
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: H3-3A
Antigen:
Histone H3K27me3
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
CG31613; CG31613 gene product from transcript CG31613-RA; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3 K27; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3c10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3f; H3-F; H3F1K; H3F2; H3F3; h3f3a; H3F3B; h3f3b.1; h3f3c; h3f3d; H3FA; H3FB; H3FC HIST1H3C; H3F
Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7
Isotype:
IgG
Purification Method:
Protein A
Product Type:
Antibody
Clone:
__
Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P02301, P68431, P68433, P84228, P84243, Q6NXT2, Q71DI3
Gene ID (Entrez):
126961, 260423, 3020, 3021, 319150, 319152, 333932, 360198, 440093, 625328, 8350, 8357, 8358, 8968, 97114
Immunogen:
This Histone H3 trimethyl Lys27 antibody was raised against a peptide including trimethyl-lysine 27 of histone H3. testing
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
H3-3A