7188788

LXR-alpha Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

LXR-alpha

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

Q13133, Q9Z0Y9

Gene ID (Entrez)

10062, 22259

Immunogen

This LXR-alpha antibody was raised against a peptide in the N-terminal region of human LXR-alpha.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

NR1H3

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

AU018371; liver X nuclear receptor alpha variant 1; Liver X receptor alpha; LXR; LXR alpha; LXRA; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; Nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; Oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Gene Symbols

NR1H3

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

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Description

  • NR1H3 (oxysterols receptor LXR-alpha) is a nuclear receptor that exhibits a ligand-dependent transcriptional activation activity
  • Its interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES
  • LXRES are DR4-type response elements characterized by direct repeats of two similar hexanucleotide half-sites spaced by four nucleotides
  • NR1H3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR, and LRP8
  • It also interplays functionally with RORA for the regulation of genes involves in liver metabolism.

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Fischer Scientific

7188788

Rabbit Polyclonal Antibody...


Antigen:
LXR-alpha

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q13133, Q9Z0Y9

Gene ID (Entrez):
10062, 22259

Immunogen:
This LXR-alpha antibody was raised against a peptide in the N-terminal region of human LXR-alpha.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
NR1H3

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
AU018371; liver X nuclear receptor alpha variant 1; Liver X receptor alpha; LXR; LXR alpha; LXRA; LXR-a; LXRalpha; LXRb; NER; NERI; NR1H2; Nr1h3; nuclear orphan receptor LXR-alpha; nuclear oxysterol receptor LxR-alpha; Nuclear receptor subfamily 1 group H member 3; nuclear receptor subfamily 1, group H, member 3; Oxysterols receptor LXR-alpha; RLD1; RLD-1; ubiquitously-expressed nuclear receptor 1; Unr1

Gene Symbols:
NR1H3

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

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Fischer Scientific

7188791

Mouse Monoclonal Antibody...


Antigen:
CtIP

Applications:
__

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q99708

Gene ID (Entrez):
5932

Immunogen:
This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Rbbp8

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
9930104E21Rik; COM1; CtBP-interacting protein; Ctip; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; Rbbp8; RBBP-8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Gene Symbols:
Rbbp8

Isotype:
IgG1

Purification Method:
Protein A

Product Type:
Antibody

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7188795

Rat Monoclonal Antibody...


Antigen:
RNA pol II

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human

Gene Accession No.:
P24928

Gene ID (Entrez):
5430

Immunogen:
This antibody was raised against a synthetic peptide containing the CTD of human RNA Polymerase II.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
POLR2A

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8

Gene Symbols:
POLR2A

Isotype:
IgG2a

Purification Method:
Protein G

Product Type:
Antibody

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7188796

Rabbit Polyclonal Antibody...


Antigen:
Histone H4K31me1

Applications:
Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
This Histone H4 monomethyl Lys31 antibody was raised against a peptide containing monomethyl Lys31 of human histone H4.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
__

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
__

Gene Symbols:
__

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody