7190609

IL-17F Monoclonal Antibody (4H450.1), Rockland™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IL-17F

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

C87042; CANDF6; Cytokine ML-1; Il17f; IL-17F; IL-24; ILN; Interleukin; interleukin 17F; Interleukin17F; Interleukin-17F; interleukin-24; ML1; ML-1; mutant IL-17F

Gene Symbols

IL17F

Isotype

IgG1

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

IL17F

Clone

4H450.1

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q96PD4

Gene ID (Entrez)

112744

Immunogen

Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.

Primary or Secondary

Primary

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antibody is specific for human IL-17F protein
  • A BLAST analysis was used to suggest cross-reactivity with IL-17F from human sources based on 100% homology with the immunizing sequence
  • Cross-reactivity with IL-17F from other sources has not been determined
  • IL-17F (Interleukin 17F, CTLA-8)) is a cytokine belonging to the IL-17 family that is produced by inflammatory cells such as activated T cells, mast cells, and basophils
  • IL-17F is involved in allergic airway inflammation, and can induce several cytokines, chemokines, and adhesion molecules in bronchial epithelial cells, vein endothelial cells, fibroblasts, and eosinophils
  • IL-17F may be secreted as a homodimer, or a heterodimer with IL17A
  • It acts by binding to the type I receptor, IL-17R, aiding recruitment of monocytes and neutrophils at the site of inflammation by increasing chemokine production
  • IL-17F also stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly suggest the involvement of IL-17 in several chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis
  • TGF-beta (differentiation) and IL-23 (expansion) are required for induction and maintenance of Th17 (IL-17 producing) cells, which in turn induce the other pro-inflammatory cytokines
  • IL-17F is produced, and exists, as a homo-dimer, with homology to a herpes virus early protein, is one of the six members (IL-17A-F) of this cytokine family, and is well characterized and highly expressed by activated effector memory T cells
  • IL-17F has been found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.

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7190609

Mouse Monoclonal Antibody...


Antigen:
IL-17F

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
C87042; CANDF6; Cytokine ML-1; Il17f; IL-17F; IL-24; ILN; Interleukin; interleukin 17F; Interleukin17F; Interleukin-17F; interleukin-24; ML1; ML-1; mutant IL-17F

Gene Symbols:
IL17F

Isotype:
IgG1

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
IL17F

Clone:
4H450.1

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q96PD4

Gene ID (Entrez):
112744

Immunogen:
Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.

Primary or Secondary:
Primary

Product Type:
Antibody

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7190610

Rabbit Polyclonal Antibody...


Antigen:
Alkaline Phosphatase

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
Akp2; Akp-2; Alkaline phosphatase 2; alkaline phosphatase 2, liver; Alkaline phosphatase liver/bone/kidney isozyme; alkaline phosphatase tissue non-specific isoform; alkaline phosphatase, biomineralization associated; alkaline phosphatase, liver/bone/kidney; Alkaline phosphatase, tissue-nonspecific isozyme; Alpl; APTNAP; AP-TNAP; BOS_2299; FLJ40094; FLJ93059; glycerophosphatase; HOPS; liver/bone/kidney isozyme; liver/bone/kidney-type alkaline phosphatase; MGC161443; MGC167935; PHOA; tissue-nonspecific alkaline phosphatase; tissue-nonspecific ALP; Tissue-nonspecific ALP alkaline phosphatase; TNAP; TNSALP; TNS-AP

Gene Symbols:
ALPL

Isotype:
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
ALPL

Clone:
__

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Bovine

Gene Accession No.:
P09487

Gene ID (Entrez):
280994

Immunogen:
Alkaline Phosphatase [Calf Intestine]

Primary or Secondary:
Primary

Product Type:
Antibody

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7190611

Rabbit Polyclonal Antibody...


Antigen:
Cyclin D3

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
9230106B05Rik; AA682053; AL024085; AW146355; C78795; CCND 3; CCND3; CGD3; cyclin D3; CyclinD3; Cyl-3; D3 type cyclin; D3-type cyclin; G1/S-specific cyclin-D3; OTTHUMP00000223415; RP5-973N23.3

Gene Symbols:
CCND3

Isotype:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
CCND3

Clone:
__

Applications:
ELISA, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P30282

Gene ID (Entrez):
12445

Immunogen:
__

Primary or Secondary:
Primary

Product Type:
Antibody

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Rabbit Polyclonal Antibody...


Antigen:
TNF alpha

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor

Gene Symbols:
Tnf

Isotype:
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
Tnf

Clone:
__

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Porcine

Gene Accession No.:
P23563

Gene ID (Entrez):
397086

Immunogen:
This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast, corresponding to 154 amino acids of mature swine TNFalpha.

Primary or Secondary:
Primary

Product Type:
Antibody