7190756
IL-17F Monoclonal Antibody (4H1629.1), Rockland™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
IL-17F
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
C87042; CANDF6; Cytokine ML-1; Il17f; IL-17F; IL-24; ILN; Interleukin; interleukin 17F; Interleukin17F; Interleukin-17F; interleukin-24; ML1; ML-1; mutant IL-17F
Gene Symbols
IL17F
Isotype
IgG1
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
IL17F
Clone
4H1629.1
Applications
ELISA, Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q96PD4
Gene ID (Entrez)
112744
Immunogen
Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody is specific for human IL-17F protein
- A BLAST analysis was used to suggest cross-reactivity with IL-17F from human sources based on 100% homology with the immunizing sequence
- Cross-reactivity with IL-17F from other sources has not been determined
- IL-17F (Interleukin 17F, CTLA-8)) is a cytokine belonging to the IL-17 family that is produced by inflammatory cells such as activated T cells, mast cells, and basophils
- IL-17F is involved in allergic airway inflammation, and can induce several cytokines, chemokines, and adhesion molecules in bronchial epithelial cells, vein endothelial cells, fibroblasts, and eosinophils
- IL-17F may be secreted as a homodimer, or a heterodimer with IL17A
- It acts by binding to the type I receptor, IL-17R, aiding recruitment of monocytes and neutrophils at the site of inflammation by increasing chemokine production
- IL-17F also stimulates induction of other pro-inflammatory cytokines TNF alpha, IL-1 beta, IL-6, and IL-8, and reports strongly suggest the involvement of IL-17 in several chronic inflammatory diseases such as rheumatoid arthritis, psoriasis and multiple sclerosis
- TGF-beta (differentiation) and IL-23 (expansion) are required for induction and maintenance of Th17 (IL-17 producing) cells, which in turn induce the other pro-inflammatory cytokines
- IL-17F is produced, and exists, as a homo-dimer, with homology to a herpes virus early protein, is one of the six members (IL-17A-F) of this cytokine family, and is well characterized and highly expressed by activated effector memory T cells
- IL-17F has been found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1.
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Antigen: IL-17F
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: C87042; CANDF6; Cytokine ML-1; Il17f; IL-17F; IL-24; ILN; Interleukin; interleukin 17F; Interleukin17F; Interleukin-17F; interleukin-24; ML1; ML-1; mutant IL-17F
Gene Symbols: IL17F
Isotype: IgG1
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: IL17F
Clone: 4H1629.1
Applications: ELISA, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q96PD4
Gene ID (Entrez): 112744
Immunogen: Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
IL-17F
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
C87042; CANDF6; Cytokine ML-1; Il17f; IL-17F; IL-24; ILN; Interleukin; interleukin 17F; Interleukin17F; Interleukin-17F; interleukin-24; ML1; ML-1; mutant IL-17F
Gene Symbols:
IL17F
Isotype:
IgG1
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
IL17F
Clone:
4H1629.1
Applications:
ELISA, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q96PD4
Gene ID (Entrez):
112744
Immunogen:
Anti-IL-17F (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-17F produced in E.coli followed by hybridoma development.
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Elastase
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias: __
Gene Symbols: __
Isotype: __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Clone: __
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: HRP
Host Species: Rabbit
Target Species: Porcine
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Elastase [Porcine Pancreas]
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Elastase
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Isotype:
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Clone:
__
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
HRP
Host Species:
Rabbit
Target Species:
Porcine
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Elastase [Porcine Pancreas]
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Gli1
Concentration: 75 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: AV235269; Gli; GLI family zinc finger 1; GLI1; GLI-Kruppel family member GLI1; Glioma-associated oncogene; glioma-associated oncogene 1; Glioma-associated oncogene homolog; glioma-associated oncogene homolog 1 (zinc finger protein); Oncogene GLI; Zfp5; Zfp-5; zinc finger protein 5; Zinc finger protein GLI1
Gene Symbols: GLI1
Isotype: __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: GLI1
Clone: __
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P08151, P47806
Gene ID (Entrez): 14632, 2735
Immunogen: The whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acids 805-820 of mouse Gli-1. The peptide was synthesized as a multiple antigen peptide (MAP).
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Gli1
Concentration:
75 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
AV235269; Gli; GLI family zinc finger 1; GLI1; GLI-Kruppel family member GLI1; Glioma-associated oncogene; glioma-associated oncogene 1; Glioma-associated oncogene homolog; glioma-associated oncogene homolog 1 (zinc finger protein); Oncogene GLI; Zfp5; Zfp-5; zinc finger protein 5; Zinc finger protein GLI1
Gene Symbols:
GLI1
Isotype:
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
GLI1
Clone:
__
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P08151, P47806
Gene ID (Entrez):
14632, 2735
Immunogen:
The whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acids 805-820 of mouse Gli-1. The peptide was synthesized as a multiple antigen peptide (MAP).
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Sprouty-2
Concentration: 1.04 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: BOS_12577; hSPRY2; IGAN3; LOC100352158; MGC23039; Protein sprouty homolog 2; sprouty 2; sprouty homolog 2; sprouty homolog 2 (Drosophila); sprouty RTK signaling antagonist 2; sprouty2; SPRY2; Spry-2
Gene Symbols: SPRY2
Isotype: __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: SPRY2
Clone: __
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O43597
Gene ID (Entrez): 10253
Immunogen: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Sprouty-2
Concentration:
1.04 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
BOS_12577; hSPRY2; IGAN3; LOC100352158; MGC23039; Protein sprouty homolog 2; sprouty 2; sprouty homolog 2; sprouty homolog 2 (Drosophila); sprouty RTK signaling antagonist 2; sprouty2; SPRY2; Spry-2
Gene Symbols:
SPRY2
Isotype:
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
SPRY2
Clone:
__
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O43597
Gene ID (Entrez):
10253
Immunogen:
__
Primary or Secondary:
Primary
Product Type:
Antibody