7190663

PLK1 Polyclonal Antibody, Rockland™

Chicken Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

PLK1

Applications

ELISA, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Chicken

Target Species

Human

Gene Accession No.

P53350

Gene ID (Entrez)

5347

Immunogen

Anti-PLK1 antibody was prepared from eggs of chickens laid after repeated immunizations with a synthetic peptide corresponding to an internal portion of human PLK1 conjugated to Keyhole Limpet Hemocyanin (KLH).

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Plk1

Concentration

1.05 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.002M sodium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7

Gene Alias

BOS_22765; cell cycle regulated protein kinase; Plk; Plk1; PLK-1; plk1.S; plx1; polo (Drosophia)-like kinase; polo like kinase; polo like kinase 1; polo like kinase 1 S homeolog; polo-like kinase; Polo-like kinase 1; polo-like kinase homolog; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase PLK1; STPK13; STPK14; XELAEV_18047692mg

Gene Symbols

Plk1

Primary or Secondary

Primary

Product Type

Antibody

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This product is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above
  • Reactivity occurs against human PLK1
  • A BLAST analysis was used to suggest cross reactivity with PLK1 protein from rat, mouse, and bovine sources based on 100% homology with the immunizing sequence
  • PLK1 is a Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis
  • Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains
  • Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55, ECT2, ERCC6L, FBXO5/EMI1, FOXM1, KIF20A/MKLP2, CENPU, NEDD1, NINL, NPM1, NUDC, PKMYT1/MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1
  • Plays a key role in centrosome functions and the assembly of bipolar spindles by phosphorylating KIZ, NEDD1 and NINL.

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Fischer Scientific

7190663

Chicken Polyclonal Antibody...


Antigen:
PLK1

Applications:
ELISA, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Chicken

Target Species:
Human

Gene Accession No.:
P53350

Gene ID (Entrez):
5347

Immunogen:
Anti-PLK1 antibody was prepared from eggs of chickens laid after repeated immunizations with a synthetic peptide corresponding to an internal portion of human PLK1 conjugated to Keyhole Limpet Hemocyanin (KLH).

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Plk1

Concentration:
1.05 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.002M sodium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7

Gene Alias:
BOS_22765; cell cycle regulated protein kinase; Plk; Plk1; PLK-1; plk1.S; plx1; polo (Drosophia)-like kinase; polo like kinase; polo like kinase 1; polo like kinase 1 S homeolog; polo-like kinase; Polo-like kinase 1; polo-like kinase homolog; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase PLK1; STPK13; STPK14; XELAEV_18047692mg

Gene Symbols:
Plk1

Primary or Secondary:
Primary

Product Type:
Antibody

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Goat Polyclonal Antibody...


Antigen:
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Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
HRP

Host Species:
Goat

Target Species:
Bacteria

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
Glucose-6-Phosphate-Dehydrogenase [Yeast]

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
__

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2

Gene Alias:
G6PD1

Gene Symbols:
__

Primary or Secondary:
Primary

Product Type:
Antibody

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Rabbit Polyclonal Antibody...


Antigen:
Phospho-Histone H2AvD (Ser137)

Applications:
ELISA, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
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Target Species:
Drosophila

Gene Accession No.:
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Gene ID (Entrez):
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Immunogen:
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Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
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Concentration:
1.1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
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Gene Symbols:
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Primary or Secondary:
Primary

Product Type:
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Antigen:
Uricase

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Bacteria

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
Uricase [Bacillus species]

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
__

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Alias:
__

Gene Symbols:
__

Primary or Secondary:
Primary

Product Type:
Antibody