7190665
Phospho-Histone H2AvD (Ser137) Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Phospho-Histone H2AvD (Ser137)
Applications
ELISA, Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Drosophila
Primary or Secondary
Primary
Product Type
Antibody
Concentration
1.1 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Affinity purified Anti-Histone H2AvD pS137 Antibody is directed against the phosphorylated form of Drosophila H2AvD protein at the pS137 residue
- Reactivity occurs against Drosophila H2AvD pS137 protein and the antibody is specific for the phosphorylated form of the protein
- Reactivity with non-phosphorylated Drosophila H2AvD is minimal by ELISA
- A BLAST analysis was used to suggest little to no cross reactivity with H2AvD proteins from other sources based on a comparison using the immunizing sequence
- Reactivity against homologues from other sources is not known
- Variant histones H2A are synthesized throughout the cell cycle and are very different from classical S-phase regulated H2A
- H2AvD is vital for viability, but the exact function of variant histones H2A is not known
- H2A is a core component of the nucleosome, an octamer containing two molecules each of H2A, H2B, H3 and H4
- The octamer wraps approximately 146 bp of DNA
- HsAvD is expressed both maternally and zygotically and is found in embryos through to adults (female only)
- The human homologue, H2AX, is phosphorylated by ATM protein kinase when double strand DNA breaks occur
- In mouse, H2AX ''knock out'' mice have an increased incidence of cancer.
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Antigen: Phospho-Histone H2AvD (Ser137)
Applications: ELISA, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Drosophila
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1.1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Antigen:
Phospho-Histone H2AvD (Ser137)
Applications:
ELISA, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Drosophila
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1.1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Antigen: Uricase
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Bacteria
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
Uricase
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Bacteria
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: Uricase
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Bacteria
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen:
Uricase
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Bacteria
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Antigen: Angiopoietin 1
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 80 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Antigen:
Angiopoietin 1
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
80 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles