7190721

MIP-1 beta Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

MIP-1 beta

Applications

ELISA, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Porcine

Gene Accession No.

Q711P4

Gene ID (Entrez)

396668

Immunogen

This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with recombinant protein raised in yeast, corresponding to the 69 amino acids of the mature swine CCL4/MIP1beta protein.

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene

CCL4

Concentration

1 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

ACT2; ACT-2; AT744.1; CC chemokine ligand 4; C-C motif chemokine 4; C-C motif chemokine ligand 4; CCL4; chemokine (C-C motif) ligand 4; G-26; G-26 T-lymphocyte-secreted protein; HC21; immune activation gene 2; Immune activation protein 2; LAG1; LAG-1; Lymphocyte activation gene 1 protein; Macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1 beta; MGC104418; MGC126025; MGC126026; MIP-1 beta; MIP1B; MIP-1B; Mip1-b; MIP1B1; MIP1beta; MIP-1BETA; MIP-1-beta; MIP1-beta; MIP-1-beta(1-69); MIP-1-beta(3-69); PAT 744; Protein H400; RP23-320E6.8; SCY4A; SCYA2; Scya4; secreted protein G-26; SIS-gamma; small inducible cytokine A4; small inducible cytokine A4 (homologous to mouse Mip-1b); Small-inducible cytokine A4; T-cell activation protein 2

Gene Symbols

CCL4

Primary or Secondary

Primary

Product Type

Antibody

Description

  • Store vial at 4°C prior to restoration
  • For extended storage aliquot contents and freeze at -20°C or below
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antibody is specific for swine CCL4 protein
  • A BLAST analysis was used to suggest cross-reactivity with CCL4 from swine sources based on 100% homology with the immunizing sequence
  • Partial reactivity is expected against horse and panda CCL4 based on 90% homology
  • Cross-reactivity with CCL4 from other sources has not been determined
  • The swine CCL4 sequence is also 86% homologous to swine CCL3L1
  • CCL4 (macrophage inflammatory protein 1-beta, MIP1B) belongs to the intercrine beta (chemokine CC) family
  • Functionally, CCL4 is involved in chemotactic and proinflammatory effects, and homeostasis
  • CCL4 is produced by macrophages upon stimulation by bacterial endotoxins
  • CCL4 recruits and stimulates various inflammatory cells at sites of inflammation
  • CCL4 is produced by lymphocytes, macrophages and dendritic cells
  • Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells
  • While both CCL4 and CCL3 exert similar effects on monocytes, their effect on lymphocytes differ, with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes
  • Additionally, both have been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells
  • The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5, thus inhibiting the CCR5-mediated entry of HIV-1 in T cells
  • CCL4 binds with high affinity to CCR5 receptors.

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7190721

Rabbit Polyclonal Antibody...


Antigen:
MIP-1 beta

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Porcine

Gene Accession No.:
Q711P4

Gene ID (Entrez):
396668

Immunogen:
This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with recombinant protein raised in yeast, corresponding to the 69 amino acids of the mature swine CCL4/MIP1beta protein.

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
CCL4

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
ACT2; ACT-2; AT744.1; CC chemokine ligand 4; C-C motif chemokine 4; C-C motif chemokine ligand 4; CCL4; chemokine (C-C motif) ligand 4; G-26; G-26 T-lymphocyte-secreted protein; HC21; immune activation gene 2; Immune activation protein 2; LAG1; LAG-1; Lymphocyte activation gene 1 protein; Macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1 beta; MGC104418; MGC126025; MGC126026; MIP-1 beta; MIP1B; MIP-1B; Mip1-b; MIP1B1; MIP1beta; MIP-1BETA; MIP-1-beta; MIP1-beta; MIP-1-beta(1-69); MIP-1-beta(3-69); PAT 744; Protein H400; RP23-320E6.8; SCY4A; SCYA2; Scya4; secreted protein G-26; SIS-gamma; small inducible cytokine A4; small inducible cytokine A4 (homologous to mouse Mip-1b); Small-inducible cytokine A4; T-cell activation protein 2

Gene Symbols:
CCL4

Primary or Secondary:
Primary

Product Type:
Antibody

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7190723

Rabbit Polyclonal Antibody...


Antigen:
Trypsinogen

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Bovine

Gene Accession No.:
__

Gene ID (Entrez):
282603, 615026

Immunogen:
Trypsinogen [Bovine Pancreas]

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
PRSS2

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
Alpha-trypsin chain 1; Alpha-trypsin chain 2; Anionic trypsin I; Anionic trypsin II; Anionic trypsin-1; Anionic trypsin-2; Anionic trypsinogen; Beta-trypsin; Cationic trypsinogen; digestive zymogen; MGC120175; MGC149362; nonfunctional trypsin 1; pancreatic trypsin 1; pancreatic trypsin 2; pancreatic trypsin II; Pretrypsinogen I; Pretrypsinogen II; Protease Serine 1; protease serine 2 preproprotein; protease, serine 1; protease, serine 1 (trypsin 1); protease, serine 2; protease, serine, 1; protease, serine, 1 (trypsin 1); protease, serine, 2; protease, serine, 2 (trypsin 2); Prss1; PRSS2; PTRYI; Ptryss2; RATPTRYI; Serine protease 1; Serine protease 2; Ta; TCR V beta 4.1; Tesp4; TRP1; TRY1; Try-1; TRY2; TRY4; TRY8; Trygn16; TRYP; TRYP1; TRYP2; TRYP8; trypsin 1; trypsin 2; Trypsin I; Trypsin II; Trypsin-1; Trypsin-2; trypsinogen 1; trypsinogen 16; trypsinogen 2; trypsinogen 20; trypsinogen A

Gene Symbols:
PRSS1, PRSS2

Primary or Secondary:
Primary

Product Type:
Antibody

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7190724

Rabbit Polyclonal Antibody...


Antigen:
PARP1 (internal)

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P09874

Gene ID (Entrez):
142

Immunogen:
PARP1 (internal) purified antibody was prepared from whole rabbit serum produced by repeated immunizations with c-terminus region of human PARP1 autocatalytic domain recombinant protein.

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Parp1

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; ADPRT; ADPRT 1; ADPRT1; AI893648; ARTD1; BOS_15645; C80510; DNA ADP-ribosyltransferase PARP1; I79_014850; msPARP; NAD(+) ADP-ribosyltransferase 1; NAD(+) pADPRT-1; pADPRT-1; Parp; PARP1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); Poly [ADP-ribose] polymerase 1; poly ADP-ribose polymerase; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein poly-ADP-ribosyltransferase PARP1; sPARP-1

Gene Symbols:
Parp1

Primary or Secondary:
Primary

Product Type:
Antibody

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7190726

Mouse Monoclonal Antibody...


Antigen:
TRPC6

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Chimpanzee, Human

Gene Accession No.:
Q9Y210

Gene ID (Entrez):
451503, 7225

Immunogen:
This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human TRPC6 protein.

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Trpc6

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
AV025995; Calcium entry channel; FLJ11098; FLJ14863; focal segmental glomerulosclerosis 2; FSGS2; HGNC:12338; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; Short transient receptor potential channel 6; transient receptor potential cation channel subfamily C member 6; transient receptor potential cation channel, subfamily C, member 6; Transient receptor protein 6; Trp6; TRP-6; trp6A; TRPC6; Trrp6

Gene Symbols:
Trpc6

Primary or Secondary:
Primary

Product Type:
Antibody