7190783
IL-1 Receptor Antagonist Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
IL-1 Receptor Antagonist
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P18510
Gene ID (Entrez)
3557
Immunogen
The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human sIL-1Ra produced in E.coli.
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
IL1RN
Concentration
1 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
Anakinra; CD121A; D2S1473; DIRA; F630041P17Rik; ICIL-1RA; IL 1 receptor antagonist; IL1 inhibitor; IL1 receptor antagonist; IL1F3; IL1R; IL1RA; Il-1ra; IL1-RA; IL-1ra3; IL-1R-alpha; Il1rn; IL-1RN; IL1RN (IL1F3); interleukin 1 receptor antagonist; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist secretory form; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); IRAP; IRAP1; MGC10430; MVCD4; P80; type II interleukin-1 receptor antagonist
Gene Symbols
IL1RN
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use. This is an IgG preparation of whole rabbit serum purified by DEAE chromatography
- In general, this antibody also detects primate IL-1Ra in the same formats using similar dilutions, but not mouse or rabbit IL-1Ra
- The antibody does not recognize human IL-1a, IL-1b or IL-1 receptor type I and type II
- This antibody is primarily directed against the secreted form of IL-1Ra (also termed sIL-1Ra) but recognizes the native (non-denatured) as well as denatured intracellular form of IL-1Ra (also termed icIL-1Ra)
- IcIL-1Ra is found in many cells as constitutively expressed protein, particularly epithelial cells and keratinocytes
- This antibody does not distinguish between sIL-1Ra and icIL-1Ra in ELISA formats or by immunohistochemistry
- When used in immunoblot analysis, it will recognize 17,000 MW IL-1Ra in supernatants released from supernatants or lysates of 2 x 106 endotoxin-stimulated human peripheral blood mononuclear cells (PBMC)
- PBMC are stimulated for 24 hours with 1% (v/v) human serum plus 10 ng/mL E.coli LPS
- However, in lysates of PBMC, icIL-1Ra is also found after 48-72 hours of culture
- In monocytic cells, the initial IL-1Ra transcript is for sIL-1Ra which can be found almost exclusively intracellularly
- The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family
- This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA)
- It is an important mediator involved in many cytokine induced immune and inflammatory responses
- This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
Compare Similar Items
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Antigen: IL-1 Receptor Antagonist
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P18510
Gene ID (Entrez): 3557
Immunogen: The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human sIL-1Ra produced in E.coli.
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: IL1RN
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: Anakinra; CD121A; D2S1473; DIRA; F630041P17Rik; ICIL-1RA; IL 1 receptor antagonist; IL1 inhibitor; IL1 receptor antagonist; IL1F3; IL1R; IL1RA; Il-1ra; IL1-RA; IL-1ra3; IL-1R-alpha; Il1rn; IL-1RN; IL1RN (IL1F3); interleukin 1 receptor antagonist; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist secretory form; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); IRAP; IRAP1; MGC10430; MVCD4; P80; type II interleukin-1 receptor antagonist
Gene Symbols: IL1RN
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
IL-1 Receptor Antagonist
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P18510
Gene ID (Entrez):
3557
Immunogen:
The whole rabbit serum used to produce this IgG fraction antibody was prepared by repeated immunizations with recombinant human sIL-1Ra produced in E.coli.
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
IL1RN
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
Anakinra; CD121A; D2S1473; DIRA; F630041P17Rik; ICIL-1RA; IL 1 receptor antagonist; IL1 inhibitor; IL1 receptor antagonist; IL1F3; IL1R; IL1RA; Il-1ra; IL1-RA; IL-1ra3; IL-1R-alpha; Il1rn; IL-1RN; IL1RN (IL1F3); interleukin 1 receptor antagonist; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist secretory form; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); IRAP; IRAP1; MGC10430; MVCD4; P80; type II interleukin-1 receptor antagonist
Gene Symbols:
IL1RN
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: NAG-1
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q99988
Gene ID (Entrez): 9518
Immunogen: __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Gdf15
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: GDF15; GDF-15; growth differentiation factor 15; Growth/differentiation factor 15; macrophage inhibiting cytokine-1; Macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; Placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; Sbf
Gene Symbols: Gdf15
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
NAG-1
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q99988
Gene ID (Entrez):
9518
Immunogen:
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Gdf15
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
GDF15; GDF-15; growth differentiation factor 15; Growth/differentiation factor 15; macrophage inhibiting cytokine-1; Macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; Placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; Sbf
Gene Symbols:
Gdf15
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Collagen Type II
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bovine, Human, Mouse, Ovine, Rat
Gene Accession No.: P02458, P02459, P05539, P28481
Gene ID (Entrez): 100196905, 1280, 12824, 25412, 407142
Immunogen: __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: Col2a1
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: alpha 1 type II procollagen; alpha 1 type IIA collagen; Alpha-1 type II collagen; ANFH; AOM; arthroophthalmopathy, progressive (Stickler syndrome); BOS_5148; cartilage collagen; CB11; CG2A1A; CGA; Chondrocalcin; COL11A3; Col2; Col2a; COL2A1; Col2a-1; Collagen 2; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen type II (Col2A1) gene, enhancer region; collagen type II alpha 1 chain; collagen, type II, alpha 1; collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital); COLLII; cyanogen bromide; Del1; disproportionate micromelia; Dmm; Lpk; M100856; MGC131516; pro-alpha 1(II); procollagen alpha 1(II); Procollagen II alpha 1; procollagen, type II, alpha 1; Rgsc856; SEDC; STL1
Gene Symbols: Col2a1
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Collagen Type II
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bovine, Human, Mouse, Ovine, Rat
Gene Accession No.:
P02458, P02459, P05539, P28481
Gene ID (Entrez):
100196905, 1280, 12824, 25412, 407142
Immunogen:
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
Col2a1
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
alpha 1 type II procollagen; alpha 1 type IIA collagen; Alpha-1 type II collagen; ANFH; AOM; arthroophthalmopathy, progressive (Stickler syndrome); BOS_5148; cartilage collagen; CB11; CG2A1A; CGA; Chondrocalcin; COL11A3; Col2; Col2a; COL2A1; Col2a-1; Collagen 2; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen type II (Col2A1) gene, enhancer region; collagen type II alpha 1 chain; collagen, type II, alpha 1; collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital); COLLII; cyanogen bromide; Del1; disproportionate micromelia; Dmm; Lpk; M100856; MGC131516; pro-alpha 1(II); procollagen alpha 1(II); Procollagen II alpha 1; procollagen, type II, alpha 1; Rgsc856; SEDC; STL1
Gene Symbols:
Col2a1
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: CXCL10
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Bovine, Goat, Ovine
Gene Accession No.: Q2KIQ8
Gene ID (Entrez): 100860873, 442997, 615107
Immunogen: This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast, corresponding to the 83 amino acids of the mature bovine CXCL10 protein.
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: CXCL10
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: 10 kDa interferon gamma-induced protein; BOS_6808; C Cmotif chemokine; C X C motif chemokine; C7; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 10; chemokine C-X-C motif ligand 10; chemokine CXC-like protein; Crg2; crg-2; CXC; CXC motif chemokine; C-X-C motif chemokine 10; C-X-C motif chemokine 10-like protein; C-X-C motif chemokine ligand 10; CXCL; Cxcl10; CXCL10(1-73); gamma interferon inducible protein 10; gamma IP10; Gamma-IP10; gIP-10; H-IP-10; Ifi10; Inp10; interferon activated gene 10; Interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; interferon-gamma-inducible protein 10; interferon-gamma-inducible protein-10; interferon-inducible cytokine IP-10; Interferon-inducible protein 10; IP10; IP-10; M-IP-10; Mob1; mob-1; protein 10 from interferon (gamma)-induced cell line; Protein Mob-1; SCYB10; small inducible cytokine B subfamily (Cys-X-Cys) member 10; small inducible cytokine B subfamily (Cys-X-Cys), member 10; small inducible c
Gene Symbols: CXCL10
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
CXCL10
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Bovine, Goat, Ovine
Gene Accession No.:
Q2KIQ8
Gene ID (Entrez):
100860873, 442997, 615107
Immunogen:
This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast, corresponding to the 83 amino acids of the mature bovine CXCL10 protein.
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
CXCL10
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
10 kDa interferon gamma-induced protein; BOS_6808; C Cmotif chemokine; C X C motif chemokine; C7; CC motif chemokine; CCmotif chemokine; chemokine (C-X-C motif) ligand 10; chemokine C-X-C motif ligand 10; chemokine CXC-like protein; Crg2; crg-2; CXC; CXC motif chemokine; C-X-C motif chemokine 10; C-X-C motif chemokine 10-like protein; C-X-C motif chemokine ligand 10; CXCL; Cxcl10; CXCL10(1-73); gamma interferon inducible protein 10; gamma IP10; Gamma-IP10; gIP-10; H-IP-10; Ifi10; Inp10; interferon activated gene 10; Interferon-gamma induced protein CRG-2; interferon-gamma-induced protein CRG-2; interferon-gamma-inducible protein 10; interferon-gamma-inducible protein-10; interferon-inducible cytokine IP-10; Interferon-inducible protein 10; IP10; IP-10; M-IP-10; Mob1; mob-1; protein 10 from interferon (gamma)-induced cell line; Protein Mob-1; SCYB10; small inducible cytokine B subfamily (Cys-X-Cys) member 10; small inducible cytokine B subfamily (Cys-X-Cys), member 10; small inducible c
Gene Symbols:
CXCL10
Primary or Secondary:
Primary
Product Type:
Antibody