7190812
Leptin Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Leptin
Applications
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
P41159, P41160
Gene ID (Entrez)
16846, 3952
Immunogen
Anti-Leptin antibody was prepared by repeated immunizations with recombinant mouse leptin 16,000 MW produced in E. coli.
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Lep
Concentration
1 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Ob; obese; Obese protein; obese, mouse, homolog of; Obesity factor; obesity protein; OB-R; OBS
Gene Symbols
Lep
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- Anti-Leptin antibody is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above
- The antibody will recognize leptin from mouse and human
- Reactivity with leptin from other sources is unknown
- Leptin is a 167 amino acid long protein hormone with important effects in regulating body weight, metabolism and reproductive function
- Leptin is approximately 16 kDa in mass and encoded by the obese (ob) gene
- Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body
- Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta
- Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells
- Leptin's effects on body weight are mediated through effects on hypothalamic centers that control feeding behavior and hunger, body temperature and energy expenditure
- Leptin is involved in regulating food intake, energy expenditure, and adiposity through hypothalamic leptin receptors
- Leptin promotes hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, influences pubertal development and fetal growth
- Studies have investigated the role of leptin in obesity, anorexia nervosa, insulin resistance, and hypertension
- Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation
- Severe hereditary obesity in rodents and humans can be caused by defects in leptin production.
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Antigen: Leptin
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P41159, P41160
Gene ID (Entrez): 16846, 3952
Immunogen: Anti-Leptin antibody was prepared by repeated immunizations with recombinant mouse leptin 16,000 MW produced in E. coli.
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Lep
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Ob; obese; Obese protein; obese, mouse, homolog of; Obesity factor; obesity protein; OB-R; OBS
Gene Symbols: Lep
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Leptin
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P41159, P41160
Gene ID (Entrez):
16846, 3952
Immunogen:
Anti-Leptin antibody was prepared by repeated immunizations with recombinant mouse leptin 16,000 MW produced in E. coli.
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Lep
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Ob; obese; Obese protein; obese, mouse, homolog of; Obesity factor; obesity protein; OB-R; OBS
Gene Symbols:
Lep
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Invertase
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Yeast
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Invertase [Candida]
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Concentration: __
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Invertase
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Yeast
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Invertase [Candida]
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Concentration:
__
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Invertase
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Yeast
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Invertase [Candida]
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Concentration: __
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Invertase
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Yeast
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Invertase [Candida]
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Concentration:
__
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Cas 9
Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Conjugate: HRP
Host Species: Rabbit
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias: APAF3; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; cas9; CASP 9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; CRISPR-Cas9; CTD; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Gene Symbols: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Cas 9
Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Conjugate:
HRP
Host Species:
Rabbit
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
APAF3; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; cas9; CASP 9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; CRISPR-Cas9; CTD; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3
Gene Symbols:
__
Primary or Secondary:
Primary
Product Type:
Antibody