7190879
Wnt1 Monoclonal Antibody (13F9), Rockland™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
Wnt1
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
BMND16; INT1; Int-1; OI15; Proto-oncogene Int-1; Proto-oncogene Int-1 homolog; proto-oncogene protein Wnt-1; Proto-oncogene Wnt-1; sw; swaying; wingless-related MMTV integration site 1; Wingless-type MMTV integration site 1 homolog; Wingless-type MMTV integration site 1, homolog; wingless-type MMTV integration site family member 1; wingless-type MMTV integration site family, member 1; wingless-type MMTV integration site family, member 1 (oncogene INT1); Wnt family member 1; WNT1; Wnt-1
Gene Symbols
WNT1
Isotype
IgG1 κ
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
WNT1
Clone
13F9
Applications
ELISA, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P04628
Gene ID (Entrez)
7471
Immunogen
Synthetic peptide corresponding to an internal region of human Wnt1 protein.
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody reacts with human and mouse Wnt1 protein
- A BLAST analysis was used to suggest cross-reactivity with Wnt1 from mouse, human, rat, bovine, dog, macaque, opossum and rat based on a 100% homology with the immunizing sequence
- Partial cross-reactivity is expected against chicken Wnt1 based on a 91% sequence homology
- Cross-reactivity with Wnt1 from other sources has not been determined
- Wnt proteins constitute a family of secreted glyocoproteins that activate signal transduction pathways to mediate tissue homeostasis, cell fate, cell proliferation, and self-renewal
- The canonical signaling pathway is initiated upon Wnt binding to a Frizzled family receptor and an LRP5/LRP6 coreceptor, which leads to activation of the beta-catenin cascade
- Non-canonical Wnt signals are activated by binding to a Frizzled family receptor and ROR2 coreceptor
- Extensive research has shown that deregulation of these pathways or its components can lead to cancer
- Human Wnt-1 is encoded as a 370 amino acid precursor that, upon secretion, is cleaved into a 343 amino acid (42 kDa) mature form
- At the amino acid level, mature human Wnt-1 is approximately 99% identical to mature mouse Wnt-1
- Depending on the tissue, Wnt-1 can activate the canonical and non-canonical signaling pathways
- Studies have demonstrated its involvement in a variety of functions, including embryonic development and carcinogenesis
- Wnt-1 signaling can also induce the phosphorylation and subsequent degradation of c-Myb.
Compare Similar Items
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Antigen: Wnt1
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: BMND16; INT1; Int-1; OI15; Proto-oncogene Int-1; Proto-oncogene Int-1 homolog; proto-oncogene protein Wnt-1; Proto-oncogene Wnt-1; sw; swaying; wingless-related MMTV integration site 1; Wingless-type MMTV integration site 1 homolog; Wingless-type MMTV integration site 1, homolog; wingless-type MMTV integration site family member 1; wingless-type MMTV integration site family, member 1; wingless-type MMTV integration site family, member 1 (oncogene INT1); Wnt family member 1; WNT1; Wnt-1
Gene Symbols: WNT1
Isotype: IgG1 κ
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: WNT1
Clone: 13F9
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P04628
Gene ID (Entrez): 7471
Immunogen: Synthetic peptide corresponding to an internal region of human Wnt1 protein.
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Wnt1
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
BMND16; INT1; Int-1; OI15; Proto-oncogene Int-1; Proto-oncogene Int-1 homolog; proto-oncogene protein Wnt-1; Proto-oncogene Wnt-1; sw; swaying; wingless-related MMTV integration site 1; Wingless-type MMTV integration site 1 homolog; Wingless-type MMTV integration site 1, homolog; wingless-type MMTV integration site family member 1; wingless-type MMTV integration site family, member 1; wingless-type MMTV integration site family, member 1 (oncogene INT1); Wnt family member 1; WNT1; Wnt-1
Gene Symbols:
WNT1
Isotype:
IgG1 κ
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
WNT1
Clone:
13F9
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P04628
Gene ID (Entrez):
7471
Immunogen:
Synthetic peptide corresponding to an internal region of human Wnt1 protein.
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Choline Oxidase
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias: __
Gene Symbols: __
Isotype: __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Clone: __
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: HRP
Host Species: Goat
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Choline Oxidase [Alcaligenes species]
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Choline Oxidase
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Isotype:
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Clone:
__
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
HRP
Host Species:
Goat
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Choline Oxidase [Alcaligenes species]
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Phospho-Muscle Glycogen Synthase (Ser641)
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
Gene Alias: EC 2.4.1.11; Glycogen [starch] synthase, muscle; glycogen synthase; glycogen synthase 1; glycogen synthase 1 (muscle); glycogen synthase 1, muscle; glycogen synthase 3, brain; GSY; Gys; GYS1; Gys3; MGS
Gene Symbols: Gys1
Isotype: __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Gys1
Clone: __
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P13807, Q9Z1E4
Gene ID (Entrez): 14936, 2997
Immunogen: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Phospho-Muscle Glycogen Synthase (Ser641)
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
Gene Alias:
EC 2.4.1.11; Glycogen [starch] synthase, muscle; glycogen synthase; glycogen synthase 1; glycogen synthase 1 (muscle); glycogen synthase 1, muscle; glycogen synthase 3, brain; GSY; Gys; GYS1; Gys3; MGS
Gene Symbols:
Gys1
Isotype:
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Gys1
Clone:
__
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P13807, Q9Z1E4
Gene ID (Entrez):
14936, 2997
Immunogen:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: NOTCH 2
Concentration: 80 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2
Gene Symbols: NOTCH2
Isotype: __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: NOTCH2
Clone: __
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q04721
Gene ID (Entrez): 4853
Immunogen: This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
NOTCH 2
Concentration:
80 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2
Gene Symbols:
NOTCH2
Isotype:
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
NOTCH2
Clone:
__
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q04721
Gene ID (Entrez):
4853
Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).
Primary or Secondary:
Primary
Product Type:
Antibody