7190883
NOTCH 2 Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
NOTCH 2
Applications
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
Q04721
Gene ID (Entrez)
4853
Immunogen
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
NOTCH2
Concentration
80 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2
Gene Symbols
NOTCH2
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antiserum is directed against human NOTCH2
- The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form
- Based on sequences, we expect this antibody to react as well with rat and mouse NOTCH 2
- Only one amino acid difference (conservative) occurs in mouse and rat
- Neurogenic locus notch homolog protein 2 (NOTCH2) is a highly conserved Notch signaling pathway protein
- NOTCH2 is a type 1 transmembrane protein with an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types
- NOTCH2 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination
- Defects in NOTCH2 are the cause of Alagille syndrome type 2 (ALGS2)
- Alagille syndrome is an autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations
- There are characteristic facial features and less frequent clinical involvement of the renal and vascular systems.
Compare Similar Items
Show Difference
Antigen: NOTCH 2
Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q04721
Gene ID (Entrez): 4853
Immunogen: This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: NOTCH2
Concentration: 80 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2
Gene Symbols: NOTCH2
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
NOTCH 2
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q04721
Gene ID (Entrez):
4853
Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
NOTCH2
Concentration:
80 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2
Gene Symbols:
NOTCH2
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: IDO1
Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Mouse
Gene Accession No.: P28776
Gene ID (Entrez): 15930
Immunogen: IDO1 antibody was produced in mouse by repeated immunizations with mouse recombinant IDO1 protein followed by hybridoma development.
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Ido1
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase
Gene Symbols: Ido1
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
IDO1
Applications:
ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Mouse
Gene Accession No.:
P28776
Gene ID (Entrez):
15930
Immunogen:
IDO1 antibody was produced in mouse by repeated immunizations with mouse recombinant IDO1 protein followed by hybridoma development.
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Ido1
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase
Gene Symbols:
Ido1
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Streptavidin
Applications: Dot Blot, ELISA, Immunofluorescence, Western Blot
Conjugate: Rhodamine
Host Species: Rabbit
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Streptavidin (Streptomyces avidinii)
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Streptavidin
Applications:
Dot Blot, ELISA, Immunofluorescence, Western Blot
Conjugate:
Rhodamine
Host Species:
Rabbit
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Streptavidin (Streptomyces avidinii)
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Streptavidin
Applications: Dot Blot, ELISA, Immunofluorescence, Western Blot
Conjugate: Rhodamine
Host Species: Rabbit
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Streptavidin (Streptomyces avidinii)
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Streptavidin
Applications:
Dot Blot, ELISA, Immunofluorescence, Western Blot
Conjugate:
Rhodamine
Host Species:
Rabbit
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Streptavidin (Streptomyces avidinii)
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Product Type:
Antibody