50-199-0073

NOTCH 2 Polyclonal Antibody, Rockland™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-199-0073-Each-of-1 In Stock ₹ 14,374.08

50-199-0073 - Each of 1

₹ 14,374.08

In Stock

Quantity

1

Base Price: ₹ 14,374.08

GST (18%): ₹ 2,587.334

Total Price: ₹ 16,961.414

Antigen

NOTCH 2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOTCH2

Gene Alias

AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2

Host Species

Rabbit

Quantity

25 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

80 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q04721

Gene Symbols

NOTCH2

Immunogen

This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).

Regulatory Status

RUO

Gene ID (Entrez)

4853

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antiserum is directed against human NOTCH2
  • The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form
  • Based on sequences, we expect this antibody to react as well with rat and mouse NOTCH 2
  • Only one amino acid difference (conservative) occurs in mouse and rat
  • Neurogenic locus notch homolog protein 2 (NOTCH2) is a highly conserved Notch signaling pathway protein
  • NOTCH2 is a type 1 transmembrane protein with an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types
  • NOTCH2 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination
  • Defects in NOTCH2 are the cause of Alagille syndrome type 2 (ALGS2)
  • Alagille syndrome is an autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations
  • There are characteristic facial features and less frequent clinical involvement of the renal and vascular systems.

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Fischer Scientific

50-199-0073

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Antigen:
NOTCH 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOTCH2

Gene Alias:
AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2

Host Species:
Rabbit

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
80 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q04721

Gene Symbols:
NOTCH2

Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).

Regulatory Status:
RUO

Gene ID (Entrez):
4853

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0074

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Antigen:
Phospho-Myosin (Ser19, Ser20)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYL12B

Gene Alias:
1500001M02Rik; 20 kDa myosin light chain; 2900073G15Rik; AI327049; AI838292; brain specific myosin regulatory light chain; C77744; C80200; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC2; MLC-2; MLC20; MLC-2A; MLC-2B; MLC-2C; MLCB; MLC-B; MRCL3; MRLC1; MRLC2; MRLC3; Mrlcb; MYL12A; Myl12b; MYL2B; MYL9; Mylc2b; Mylc2c; myosin light chain 12A; myosin light chain 12B; myosin light chain 9; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; Myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; Myosin regulatory light chain 20 kDa; Myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; Myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; Myosin regulatory light chain RLC-A; myosin regulatory light chain-B; Myosin regulatory light polypeptide 9; Myosin RLC; Myosin RLC-A; Myosin RLC-B; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light chain 12B, regulatory; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); Myrl2; NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; RLC-B; RLC-C; SHUJUN-1

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
70 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
O14950, P19105, P24844

Gene Symbols:
MYL12A, MYL12B, MYL9

Immunogen:
Human Myosin Light Chain phospho peptide corresponding to a region near the amino terminus of the human smooth/non-muscle form of myosin regulatory light chain conjugated to Keyhole Limpet Hemocyanin (KLH).

Regulatory Status:
RUO

Gene ID (Entrez):
103910, 10398, 10627

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0076

--


Antigen:
ZBP-89

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF148

Gene Alias:
2210405J08Rik; AI480666; AW045217; BERF-1; Beta enolase repressor factor 1; BFCOL1; BOS_850; CACCC box-binding protein; CLL-associated antigen KW-10; fb06h05; G-rich box-binding protein; HT-BETA; LOC100344423; pHZ-52; si:dkey-101k6.6; Transcription factor BFCOL1; Transcription factor ZBP-89; wu:fb06h05; zbp89; Zbp-89; Zfp148; zfp149; zgc:165342; zinc finger binding protein 89; zinc finger DNA binding protein 89; Zinc finger DNA-binding protein 89; Zinc finger protein 148; Znf148

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Western Blot

Concentration:
90 mg/mL

Formulation:
Antibody with 0.1% sodium azide; pH

Gene Accession No.:
Q9UQR1

Gene Symbols:
ZNF148

Immunogen:
Purified full length ZBP-89 recombinant protein expressed in E.coli.

Regulatory Status:
RUO

Gene ID (Entrez):
7707

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-199-0077

--


Antigen:
Stat4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT4

Gene Alias:
CIS4; HSPC060; OTTHUMP00000163553; Signal transducer and activator of transcription 4; SLEB11; SOCS4; SOCS6; SSI4; STAI4; STAT; STAT4; STATI4

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
85 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
P42228

Gene Symbols:
STAT4

Immunogen:
This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-Terminal region near amino acids 725-749 of Mouse STAT-4.

Regulatory Status:
RUO

Gene ID (Entrez):
20849

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid