50-194-3773

NOTCH 2 Polyclonal Antibody, Rockland™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 50-194-3773-Each-of-1 In Stock ₹ 50,884.24

50-194-3773 - Each of 1

₹ 50,884.24

In Stock

Quantity

1

Base Price: ₹ 50,884.24

GST (18%): ₹ 9,159.163

Total Price: ₹ 60,043.403

Antigen

NOTCH 2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOTCH2

Gene Alias

AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2

Host Species

Rabbit

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Applications

ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

80 mg/mL

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.

Q04721

Gene Symbols

NOTCH2

Immunogen

This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).

Regulatory Status

RUO

Gene ID (Entrez)

4853

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antiserum is directed against human NOTCH2
  • The immunogen epitope is only exposed after gamma secretase cleavage and is not accessible in the uncleaved form
  • Based on sequences, we expect this antibody to react as well with rat and mouse NOTCH 2
  • Only one amino acid difference (conservative) occurs in mouse and rat
  • Neurogenic locus notch homolog protein 2 (NOTCH2) is a highly conserved Notch signaling pathway protein
  • NOTCH2 is a type 1 transmembrane protein with an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types
  • NOTCH2 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination
  • Defects in NOTCH2 are the cause of Alagille syndrome type 2 (ALGS2)
  • Alagille syndrome is an autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations
  • There are characteristic facial features and less frequent clinical involvement of the renal and vascular systems.

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Show Difference

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Fischer Scientific

50-194-3773

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Antigen:
NOTCH 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOTCH2

Gene Alias:
AGS2; AI853703; HJCYS; hN2; Motch B; N2; N2ECD; N2ICD; Neurogenic locus notch homolog protein 2; Notch 2; Notch 2 extracellular truncation; Notch 2 intracellular domain; notch gene homolog 2; Notch homolog 2; Notch2

Host Species:
Rabbit

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
80 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
Q04721

Gene Symbols:
NOTCH2

Immunogen:
This whole rabbit serum was prepared by repeated immunizations with a synthetic peptide corresponding to amino acid residues of human Notch 2 located near the N-terminal sequence of the cleaved N intracellular domain (NICD).

Regulatory Status:
RUO

Gene ID (Entrez):
4853

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-194-3774

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Antigen:
Biotin Ligase Epitope Tag

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
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Gene Alias:
__

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Applications:
ELISA, Western Blot

Concentration:
70 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Anti-BIOTIN Ligase Epitope Tag antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide GLNDIFEAQKIEWH (minimal BirA substrate; biotin is added to the sequence at the lysine.)

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Rockland Immunochemicals

50-194-3775

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Antigen:
__

Classification:
__

Conjugate:
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Gene:
__

Gene Alias:
__

Host Species:
__

Quantity:
__

Primary or Secondary:
__

Target Species:
__

Product Type:
__

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
__

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Rockland Immunochemicals

50-194-3776

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Antigen:
E.coli Combined HCP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
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Gene Alias:
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Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
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Applications:
ELISA, Immunoprecipitation, Western Blot

Concentration:
76 mg/mL

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Regulatory Status:
RUO

Gene ID (Entrez):
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Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Form:
Liquid