7191024
NEDD4 Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
NEDD4
Applications
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Equine, Human, Rhesus Monkey
Gene Accession No.
P46934
Gene ID (Entrez)
100054735, 4734, 699550
Primary or Secondary
Primary
Product Type
Antibody
Concentration
0.64 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
AA959633; AL023035; AU019897; Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; Nedd4; Nedd-4; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1
Gene Symbols
NEDD4
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
NEDD4
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody reacts with endogenous Nedd4 protein
- A BLAST analysis was used to suggest reactivity with Nedd4 from human, horse and macaque based on a 100% homology with the immunizing sequence
- Expect reactivity with Nedd4 from chimpanzee, rabbit, dog, and cattle based on a 94% homology with the immunizing sequence
- Cross-reactivity with Nedd4 from other sources has not been determined
- The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein
- It contains one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains
- It is involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity
- It acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53
- It is also reported to be involved in the budding of many viruses and is the regulator of epithelial Na+ channels, which lead to arterial hypertension
- NEDD4 protein is localized to the sarcolemmal region of muscle fibers
- Increase in NEDD4 protein expression leads to unloaded and denervated muscles as well as a decrease in Notch1 expression
- Hence it acts as down regulator of Notch-1 gene expression.
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Antigen: NEDD4
Applications: ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Equine, Human, Rhesus Monkey
Gene Accession No.: P46934
Gene ID (Entrez): 100054735, 4734, 699550
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 0.64 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: AA959633; AL023035; AU019897; Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; Nedd4; Nedd-4; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1
Gene Symbols: NEDD4
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: NEDD4
Antigen:
NEDD4
Applications:
ELISA, Immunofluorescence, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Equine, Human, Rhesus Monkey
Gene Accession No.:
P46934
Gene ID (Entrez):
100054735, 4734, 699550
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
0.64 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
AA959633; AL023035; AU019897; Cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; Nedd4; Nedd-4; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1
Gene Symbols:
NEDD4
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
NEDD4
Antigen: Caspase 12
Applications: ELISA, Immunofluorescence, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse, Rat
Gene Accession No.: O08736, Q920D5
Gene ID (Entrez): 12364, 156117
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: CASP12; CASP-12; CASP12P1; caspase 12; caspase 12 (gene/pseudogene); caspase 12 pseudogene 1; Caspase-12; Inactive caspase-12; OTTMUSP00000045799; OTTMUSP00000045802; OTTMUSP00000045803; UNQ9415; UNQ9415/PRO34398
Gene Symbols: CASP12
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: CASP12
Antigen:
Caspase 12
Applications:
ELISA, Immunofluorescence, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse, Rat
Gene Accession No.:
O08736, Q920D5
Gene ID (Entrez):
12364, 156117
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
CASP12; CASP-12; CASP12P1; caspase 12; caspase 12 (gene/pseudogene); caspase 12 pseudogene 1; Caspase-12; Inactive caspase-12; OTTMUSP00000045799; OTTMUSP00000045802; OTTMUSP00000045803; UNQ9415; UNQ9415/PRO34398
Gene Symbols:
CASP12
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
CASP12
Antigen: Fibrinogen
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Human
Gene Accession No.: P02671, P02675, P02679
Gene ID (Entrez): 2243, 2244, 2266
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias: 2510049G14Rik; 3010002H13Rik; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78p; Fba5e; FGA; Fgb; FGG; Fib; Fib2; Fibrinogen alpha chain; Fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; gamma-fibrinogen; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70
Gene Symbols: FGA, FGB, FGG
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: FGB
Antigen:
Fibrinogen
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
P02671, P02675, P02679
Gene ID (Entrez):
2243, 2244, 2266
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias:
2510049G14Rik; 3010002H13Rik; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78p; Fba5e; FGA; Fgb; FGG; Fib; Fib2; Fibrinogen alpha chain; Fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; gamma-fibrinogen; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70
Gene Symbols:
FGA, FGB, FGG
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
FGB
Antigen: ERK2 Internal
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse, Rat
Gene Accession No.: P28482, P63085, P63086
Gene ID (Entrez): 116590, 26413, 5594
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: 9030612K14Rik; AA407128; AU018647; C78273; ERK; Erk2; ERK-2; ERT1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase-2; extracellular-signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; Mapk; MAPK 1; MAPK 2; MAPK1; MAPK2; mitogen activated protein kinase 1; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; p38; p40; p41; p41mapk; p42mapk; p42-MAPK; PRKM1; PRKM2; protein tyrosine kinase ERK2
Gene Symbols: MAPK1
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: MAPK1
Antigen:
ERK2 Internal
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse, Rat
Gene Accession No.:
P28482, P63085, P63086
Gene ID (Entrez):
116590, 26413, 5594
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
9030612K14Rik; AA407128; AU018647; C78273; ERK; Erk2; ERK-2; ERT1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase-2; extracellular-signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; Mapk; MAPK 1; MAPK 2; MAPK1; MAPK2; mitogen activated protein kinase 1; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; p38; p40; p41; p41mapk; p42mapk; p42-MAPK; PRKM1; PRKM2; protein tyrosine kinase ERK2
Gene Symbols:
MAPK1
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
MAPK1