7191025

Caspase 12 Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Caspase 12

Applications

ELISA, Immunofluorescence, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Mouse, Rat

Gene Accession No.

O08736, Q920D5

Gene ID (Entrez)

12364, 156117

Primary or Secondary

Primary

Product Type

Antibody

Concentration

1 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

CASP12; CASP-12; CASP12P1; caspase 12; caspase 12 (gene/pseudogene); caspase 12 pseudogene 1; Caspase-12; Inactive caspase-12; OTTMUSP00000045799; OTTMUSP00000045802; OTTMUSP00000045803; UNQ9415; UNQ9415/PRO34398

Gene Symbols

CASP12

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

CASP12

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This affinity purified antibody is directed against mouse Caspase 12
  • A BLAST analysis was used to suggest reactivity with the antigen based on 100% homology with the immunizing sequence
  • Three distinct signaling pathways lead to programmed cell death (apoptosis)
  • The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved
  • The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved
  • Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion
  • Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis
  • Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including -gamma-secretase presenilin and beta-amyloid precursor protein (APP)
  • Caspase-12 mediates cytotoxicity induced by amyloid-beta
  • Caspase-12 is ubiquitously expressed in mouse tissues.

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Show Difference

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Fischer Scientific

7191025

Rabbit Polyclonal Antibody...


Antigen:
Caspase 12

Applications:
ELISA, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse, Rat

Gene Accession No.:
O08736, Q920D5

Gene ID (Entrez):
12364, 156117

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
CASP12; CASP-12; CASP12P1; caspase 12; caspase 12 (gene/pseudogene); caspase 12 pseudogene 1; Caspase-12; Inactive caspase-12; OTTMUSP00000045799; OTTMUSP00000045802; OTTMUSP00000045803; UNQ9415; UNQ9415/PRO34398

Gene Symbols:
CASP12

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
CASP12

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7191026

Goat Polyclonal Antibody...


Antigen:
Fibrinogen

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Biotin

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
P02671, P02675, P02679

Gene ID (Entrez):
2243, 2244, 2266

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Alias:
2510049G14Rik; 3010002H13Rik; Ab1-181; Ab1-216; Ac1-581; Ac1873; AI256424; ENSMUSG00000059807; epididymis secretory sperm binding protein Li 78p; Fba5e; FGA; Fgb; FGG; Fib; Fib2; Fibrinogen alpha chain; Fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen gamma-chain; fibrinogen, A alpha polypeptide; fibrinogen, alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, beta polypeptide; fibrinogen, gamma polypeptide; Fibrinopeptide A; Fibrinopeptide B; gamma-fibrinogen; HEL-S-78p; Liver regeneration-related protein LRRG036/LRRG043/LRRG189; MGC119422; MGC119423; MGC119425; PRO2061; testicular tissue protein Li 70

Gene Symbols:
FGA, FGB, FGG

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
FGB

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7191029

Mouse Monoclonal Antibody...


Antigen:
ERK2 Internal

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P28482, P63085, P63086

Gene ID (Entrez):
116590, 26413, 5594

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
9030612K14Rik; AA407128; AU018647; C78273; ERK; Erk2; ERK-2; ERT1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase-2; extracellular-signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; Mapk; MAPK 1; MAPK 2; MAPK1; MAPK2; mitogen activated protein kinase 1; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; p38; p40; p41; p41mapk; p42mapk; p42-MAPK; PRKM1; PRKM2; protein tyrosine kinase ERK2

Gene Symbols:
MAPK1

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
MAPK1

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7191031

Rabbit Polyclonal Antibody...


Antigen:
alpha Amylase

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Biotin

Host Species:
Rabbit

Target Species:
Bacteria

Gene Accession No.:
__

Gene ID (Entrez):
__

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Alias:
1,4-alpha-D-glucan glucanohydrolase; 1,4-alpha-D-glucan glucanohydrolase 2B; a-amylase; alpha-amylase; Alpha-amylase 2B; Amy2; Amy2-1; Amy2-2; Amy2a; Amy2a1; Amy2a3; AMY2B; AMY3; amylase 2, pancreatic; amylase 2-2, pancreatic; amylase 2a1; amylase 2a3; amylase 2a3, pancreatic; amylase 2b; amylase 2b, pancreatic; amylase, alpha 2A (pancreatic); amylase, alpha 2B (pancreatic); Amy-X; Carcinoid alpha-amylase; glycogenase; HXA; mAmy2-1; mAmy2-4; mAmy2-6; OTTMUSG00000022430; OTTMUSG00000022432; OTTMUSG00000022462; PA; Pancreatic alpha-amylase; pancreatic amylase; pancreatic amylase alpha 2A

Gene Symbols:
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
__