PD-L2/B7-DC/PDCD1LG2 Antibody (TY25) - BSA Free, Novus Biologicals™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
PD-L2/B7-DC/PDCD1LG2
Concentration
1.0 mg/mL
Applications
Immunohistochemistry (Frozen), Immunohistochemistry, Immunoprecipitation, Flow Cytometry
Conjugate
Unconjugated
Host Species
Rat
Target Species
Mouse
Gene ID (Entrez)
80380
Immunogen
B7-DC transfected RAW264.7 cells.
Primary or Secondary
Primary
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Clone
TY25
Dilution
Flow Cytometry 1:100-1:200, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Gene Alias
B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2
Gene Symbols
PDCD1LG2
Isotype
IgG2a
Purification Method
Protein G purified
Test Specificity
NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.
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Description
- PD-L2/B7-DC/PDCD1LG2 Monoclonal specifically detects PD-L2/B7-DC/PDCD1LG2 in Mouse samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Immunohistochemistry-Frozen.
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Antigen: PD-L2/B7-DC/PDCD1LG2
Concentration: 1.0 mg/mL
Applications: Immunohistochemistry (Frozen), Immunohistochemistry, Immunoprecipitation, Flow Cytometry
Conjugate: Unconjugated
Host Species: Rat
Target Species: Mouse
Gene ID (Entrez): 80380
Immunogen: B7-DC transfected RAW264.7 cells.
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Clone: TY25
Dilution: Flow Cytometry 1:100-1:200, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Gene Alias: B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2
Gene Symbols: PDCD1LG2
Isotype: IgG2a
Purification Method: Protein G purified
Test Specificity: NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.
Antigen: Salmonella Enteritidis
Concentration: __
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Bacteria
Gene ID (Entrez): __
Immunogen: Heat inactivated cells from Salmonella (LPS groups A, B & D).
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Clone: 10D9H (E91)
Dilution: Western Blot 1:100-1:2000, ELISA 1:100-1:2000
Classification: Monoclonal
Form: __
Regulatory Status: RUO
Gene Alias: __
Gene Symbols: __
Isotype: IgG1
Purification Method: Affinity Purified
Test Specificity: This antibody recognizes a common antigenic determinant that is found in the LPS of Salmonella enteriditis (Group D), Salmonella typhimurium (Group B) and Salmonella paratyphi (Group A) . This antibody is thought to recognize the '0-12' antigen [2-D-mannose (1-4) I- ramnose (1-3)-D galactose] of salmonella LPS. A similar sequence is found in Group E, which may account for the weak cross reactivity observed with bacteria of this group.
Antigen: Salmonella Enteritidis
Concentration: __
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Bacteria
Gene ID (Entrez): __
Immunogen: Heat inactivated cells from Salmonella (LPS groups A, B & D).
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Clone: 10D9H (E91)
Dilution: Western Blot 1:100-1:2000, ELISA 1:100-1:2000
Classification: Monoclonal
Form: __
Regulatory Status: RUO
Gene Alias: __
Gene Symbols: __
Isotype: IgG1
Purification Method: Affinity Purified
Test Specificity: This antibody recognizes a common antigenic determinant that is found in the LPS of Salmonella enteriditis (Group D), Salmonella typhimurium (Group B) and Salmonella paratyphi (Group A) . This antibody is thought to recognize the '0-12' antigen [2-D-mannose (1-4) I- ramnose (1-3)-D galactose] of salmonella LPS. A similar sequence is found in Group E, which may account for the weak cross reactivity observed with bacteria of this group.