Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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ILT5/CD85a/LILRB3
1.0 mg/mL
Immunohistochemistry (Frozen), Immunohistochemistry, Flow Cytometry
Unconjugated
Mouse
Human
CD85 antigen-like family member A, CD85a antigen, HL9Immunoglobulin-like transcript 5, ILT-5, ILT5CD85a, Leukocyte immunoglobulin-like receptor 3, leukocyte immunoglobulin-like receptor subfamily B member 3, leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), LIR3CD85A, LIR-3MGC138403, member 3, Monocyte inhibitory receptor HL9, PIRB
LILRB3
IgG1
Protein G purified
NB100-64329 is specific for human CD85a (leucocyte immunoglobulin-like receptor, subfamily B, member 3/ LILRB3), also known as ILT-5, expressed by monocytes, dendritic cells, macrophages, subpopulation of T lymphocytes, B cells and at high levels on plasma cells. CD85a is a 631 amino acid type I transmembrane glycoprotein, which contains four immunoreceptor tyrosine-based inhibition motif (ITIM) sequences within a long cytoplasmic tail. Phosphorylation of the tyrosine residues within ITIMs is known to enable the binding and activation of protein tyrosine phosphatases, which act as cell signalling modulators and inhibitors of cell activation.
4F9
Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:100
Monoclonal
Purified
RUO
Q8NHL6
11025
Monocyte derived dendritic cells
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.