7200583

Shigella Antibody (306/305) - BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Shigella

Concentration

1.0 mg/mL

Applications

ELISA

Conjugate

Unconjugated

Regulatory Status

RUO

Gene Alias

Shigella Boydii; Shigella Dysenteriae; Shigella Flexneri; Shigella Sonnei

Isotype

IgG1

Purification Method

Affinity Purified

Test Specificity

This product is specific for Shigella flexneri serotype 6. S. flexneri is a gram negative, rod shaped bacteria that is very closely related to E. coli and Salmonella.

Clone

306/305

Dilution

ELISA 1:100-1:2000

Classification

Monoclonal

Host Species

Mouse

Target Species

Bacteria

Immunogen

NCTC 9729

Primary or Secondary

Primary

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Description

  • Shigella Monoclonal specifically detects Shigella in Bacteria samples
  • It is validated for ELISA.

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Fischer Scientific

7200583

Mouse Monoclonal Antibody...


Antigen:
Shigella

Concentration:
1.0 mg/mL

Applications:
ELISA

Conjugate:
Unconjugated

Regulatory Status:
RUO

Gene Alias:
Shigella Boydii; Shigella Dysenteriae; Shigella Flexneri; Shigella Sonnei

Isotype:
IgG1

Purification Method:
Affinity Purified

Test Specificity:
This product is specific for Shigella flexneri serotype 6. S. flexneri is a gram negative, rod shaped bacteria that is very closely related to E. coli and Salmonella.

Clone:
306/305

Dilution:
ELISA 1:100-1:2000

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Bacteria

Immunogen:
NCTC 9729

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Img

Fischer Scientific

7200587

Mouse Monoclonal Antibody...


Antigen:
SerpinB9

Concentration:
1.0 mg/mL

Applications:
Immunohistochemistry (Frozen), Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Flow Cytometry

Conjugate:
Unconjugated

Regulatory Status:
RUO

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Isotype:
IgG1

Purification Method:
Protein G purified

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kDa under reducing conditions. Clone 7D8 is suitable for use in indirect Immunofluorescence (2).

Clone:
7D8

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:50, Immunohistochemistry-Frozen 1:10-1:500

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Mouse (Negative), Porcine (Negative), Human

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Img

Fischer Scientific

7200587

Mouse Monoclonal Antibody...


Antigen:
SerpinB9

Concentration:
1.0 mg/mL

Applications:
Immunohistochemistry (Frozen), Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Flow Cytometry

Conjugate:
Unconjugated

Regulatory Status:
RUO

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Isotype:
IgG1

Purification Method:
Protein G purified

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kDa under reducing conditions. Clone 7D8 is suitable for use in indirect Immunofluorescence (2).

Clone:
7D8

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:50, Immunohistochemistry-Frozen 1:10-1:500

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Mouse (Negative), Porcine (Negative), Human

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Img

Fischer Scientific

7200587

Mouse Monoclonal Antibody...


Antigen:
SerpinB9

Concentration:
1.0 mg/mL

Applications:
Immunohistochemistry (Frozen), Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Flow Cytometry

Conjugate:
Unconjugated

Regulatory Status:
RUO

Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9

Isotype:
IgG1

Purification Method:
Protein G purified

Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kDa under reducing conditions. Clone 7D8 is suitable for use in indirect Immunofluorescence (2).

Clone:
7D8

Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:50, Immunohistochemistry-Frozen 1:10-1:500

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Mouse (Negative), Porcine (Negative), Human

Immunogen:
Recombinant PI-9 produced in P. pastoris.

Primary or Secondary:
Primary

Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.