CLEC10A/CD301 Antibody (ER-MP23) - BSA Free, Novus Biologicals™
Rat Monoclonal Antibody has been used in 1 publication
Manufacturer: Fischer Scientific
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Antigen
CLEC10A/CD301
Concentration
1.0 mg/mL
Applications
Immunofluorescence, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rat
Target Species
Mouse
Gene ID (Entrez)
10462
Immunogen
Balb/c macrophage precursor cell hybrids
Primary or Secondary
Primary
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Clone
ER-MP23
Dilution
Flow Cytometry, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Classification
Monoclonal
Form
Purified
Regulatory Status
RUO
Gene Alias
CD301 antigen, CD301C-type lectin domain family 10 member A, CLECSF13, CLECSF14macrophage C-type lectin, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 14 (macrophage-derived), C-type lectin domain family 10, member A, C-type lectin superfamily member 14, HML2, HMLC-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 13 (macrophage-derived), Macrophage lectin 2, macrophage lectin 2 (calcium dependent), MGL
Gene Symbols
CLEC10A
Isotype
IgG2a
Purification Method
Protein G purified
Test Specificity
NB100-64874 recognizes murine CD301, a 38 kD cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR). In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated. Clone ER-MP23 is reported to block the function of mouse CD301. The antibody binds both MGL1 and MGL2 homologues.
Related Products
Description
- CLEC10A/CD301 Monoclonal specifically detects CLEC10A/CD301 in Mouse samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen.
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Antigen: CLEC10A/CD301
Concentration: 1.0 mg/mL
Applications: Immunofluorescence, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rat
Target Species: Mouse
Gene ID (Entrez): 10462
Immunogen: Balb/c macrophage precursor cell hybrids
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Clone: ER-MP23
Dilution: Flow Cytometry, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Gene Alias: CD301 antigen, CD301C-type lectin domain family 10 member A, CLECSF13, CLECSF14macrophage C-type lectin, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 14 (macrophage-derived), C-type lectin domain family 10, member A, C-type lectin superfamily member 14, HML2, HMLC-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 13 (macrophage-derived), Macrophage lectin 2, macrophage lectin 2 (calcium dependent), MGL
Gene Symbols: CLEC10A
Isotype: IgG2a
Purification Method: Protein G purified
Test Specificity: NB100-64874 recognizes murine CD301, a 38 kD cell surface protein that is otherwise known as macrophage galactose N-acetylgalactosamine lectin (MGL) or dendritic cell asialoglycoprotein (DC-ASGPR). In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated. Clone ER-MP23 is reported to block the function of mouse CD301. The antibody binds both MGL1 and MGL2 homologues.
Antigen: Integrin alpha 4/CD49d
Concentration: 1.0 mg/mL
Applications: Immunohistochemistry (Paraffin), Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene ID (Entrez): 3676
Immunogen: HOON pre-B leukemia cell line
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Clone: 44H6
Dilution: Flow Cytometry 1:40, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Frozen 1:50-1:100, Immunohistochemistry-Paraffin (Negative)
Classification: Monoclonal
Form: Purified
Regulatory Status: RUO
Gene Alias: 269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Gene Symbols: ITGA4
Isotype: IgG1
Purification Method: Protein A or G purified
Test Specificity: NB100-64903 recognizes CD49d, also known as Integrin alpha 4, which associates with either CD29 (integrin beta 1) or integrin beta 7. CD49d is a 150kD molecule, which may be cleaved to 80kD and 70kD fragments. It is expressed by lymphocytes, monocytes, eosinophils and thymocytes. VLA-4 mediates cell adhesion to VCAM-1 and fibronectin. 44H6 induces homotypic aggregation.
Antigen: NFkB p105/p50 (p Ser927)
Concentration: 1.0 mg/mL
Applications: Western Blot, Immunocytochemistry, Immunohistochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Rat, Mouse, Human
Gene ID (Entrez): 4790
Immunogen: __
Primary or Secondary: Primary
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Clone: __
Dilution: Western Blot 1:500-1:1000, Immunohistochemistry 1:50-1:100, Immunocytochemistry/Immunofluorescence 1:100-1:200, Immunohistochemistry-Paraffin 1:50-1:100
Classification: Polyclonal
Form: __
Regulatory Status: RUO
Gene Alias: DKFZp686C01211, DNA binding factor KBF1, DNA-binding factor KBF1, EBP-1, KBF1, NF-kappaB, NF-kappa-B, NF-kappabeta, NFKB-p105, NFKB-p50, nuclear factor kappa-B DNA binding subunit, nuclear factor NF-kappa-B p105 subunit, nuclear factor NF-kappa-B p50 subunit, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1MGC54151, p105, p50
Gene Symbols: NFKB1
Isotype: IgG
Purification Method: Affinity Purified
Test Specificity: __
