7214628

CD11c Mouse, anti-Human, R718, Clone: B-ly6, BD Horizon™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD11c

Applications

Flow Cytometry

Conjugate

R718

Host Species

Mouse

Target Species

Human

Content And Storage

Refrigerate Upon Arrival

Clone

B-ly6

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Primary or Secondary

Primary

Description

  • The B-ly6 monoclonal antibody specifically binds to the 150 kDa adhesion glycoprotein CD11c (p150, integrin α chain)
  • CD11c is expressed on dendritic cells, monocytes, macrophages, granulocytes, NK cells and subsets of B and T cells
  • It associates with CD18 to form the CD11c/CD18 complex that binds fibrinogen and has been reported to be a receptor for iC3b and ICAM-1
  • Reports indicate that CD11c/CD18 plays a role as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium.

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Clone:
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Form:
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