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Antigen
CD11c
Applications
Flow Cytometry
Conjugate
R718
Host Species
Mouse
Target Species
Human
Content And Storage
Refrigerate Upon Arrival
Clone
B-ly6
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Primary or Secondary
Primary
Description
The B-ly6 monoclonal antibody specifically binds to the 150 kDa adhesion glycoprotein CD11c (p150, integrin α chain)
CD11c is expressed on dendritic cells, monocytes, macrophages, granulocytes, NK cells and subsets of B and T cells
It associates with CD18 to form the CD11c/CD18 complex that binds fibrinogen and has been reported to be a receptor for iC3b and ICAM-1
Reports indicate that CD11c/CD18 plays a role as an adhesion molecule that mediates cellular binding to ligands expressed on stimulated epithelium and endothelium.