7215067

Phospho-CREB (Ser133) Recombinant Rabbit Monoclonal Antibody (CREBS133-4D11), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-CREB (Ser133)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias

2310001E10Rik; 3526402H21Rik; active transcription factor CREB; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; htCREB; MGC9284; OTTHUMP00000206661; OTTHUMP00000206662; OTTHUMP00000206667; transactivator protein; Y protein

Gene Symbols

CREB1

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

CREBS133-4D11

Applications

Flow Cytometry, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P16220, Q01147

Gene ID (Entrez)

12912, 1385

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser133 of human phospho CREB.

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

CREB1

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Description

  • CREB (Cyclic AMP response element binding protein) is a 43 kDa basic/leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth and neurotrophic factors
  • Activation of CREB is dependent upon the phosphorylation of serine 133
  • Phosphorylation of CREB occurs via p44/42 MAP kinase and p90RSK, and via p38 MAP kinase and MSK1
  • Although CREB will bind DNA independent of its phosphorylation state, only the phosphorylated form is competent as a transcription factor
  • CREB binding protein (CBP), a transcriptional coactivator that directly interacts with CREB, binds to CREB in the region of serine 133
  • CREB is involved in different cellular processes including the synchronization of circadian rhythmicity, differentiation of adipose cells, and learning and memory
  • In humans, the gene is located on the q arm of chromosome 2
  • Diseases associated with CREB dysfunction include Alzheimer’s Disease, histiocytoma and soft tissue melanoma.

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Img

Fischer Scientific

7215067

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-CREB (Ser133)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
2310001E10Rik; 3526402H21Rik; active transcription factor CREB; AV083133; cAMP response element binding protein 1; cAMP responsive element binding protein 1; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; CREB; CREB1; Creb-1; cyclic adenosine 3',5'-monophosphate response element-binding protein CREB; cyclic AMP-responsive element-binding protein 1; htCREB; MGC9284; OTTHUMP00000206661; OTTHUMP00000206662; OTTHUMP00000206667; transactivator protein; Y protein

Gene Symbols:
CREB1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
CREBS133-4D11

Applications:
Flow Cytometry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P16220, Q01147

Gene ID (Entrez):
12912, 1385

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser133 of human phospho CREB.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
CREB1

Img

Fischer Scientific

7215068

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Histone H3 (Ser10)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
BUR5; CG31613; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; CG5825; CG5825-PA; CG5825-PC; CG5825-PD; CG8989; dH3.3A; Dmel\CG31613; Dmel\CG5825; Dmel_CG31613; Dmel_CG5825; fb58e10; h3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3; H3.3 histone A; H3.3 histone B; H3.3a; H3.3B; H3.5; H3.5 histone; H3.A; H3.B; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-5; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3c10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6

Gene Symbols:
H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7, HIST1H3A

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
HisH3S10-4B6

Applications:
Flow Cytometry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P68431, Q71DI3

Gene ID (Entrez):
126961, 333932, 8350, 8356, 8357, 8358, 8968

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser10 of human phospho histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
H3C15

Img

Fischer Scientific

7215068

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Histone H3 (Ser10)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
BUR5; CG31613; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; CG5825; CG5825-PA; CG5825-PC; CG5825-PD; CG8989; dH3.3A; Dmel\CG31613; Dmel\CG5825; Dmel_CG31613; Dmel_CG5825; fb58e10; h3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3; H3.3 histone A; H3.3 histone B; H3.3a; H3.3B; H3.5; H3.5 histone; H3.A; H3.B; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-5; H3-53; H3-614; H3a; H3b; H3-B; H3C1; H3c10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6

Gene Symbols:
H3C1, H3C10, H3C12, H3C14, H3C15, H3C2, H3C7, HIST1H3A

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
HisH3S10-4B6

Applications:
Flow Cytometry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P68431, Q71DI3

Gene ID (Entrez):
126961, 333932, 8350, 8356, 8357, 8358, 8968

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser10 of human phospho histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
H3C15

Img

Fischer Scientific

7215069

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Stat5 (Tyr694)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Gene Symbols:
STAT5A

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
Stat5Y694-G11

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P42229, P42230

Gene ID (Entrez):
20850, 6776

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr694 of human phospho Stat5.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
STAT5A