7215069

Phospho-Stat5 (Tyr694) Recombinant Rabbit Monoclonal Antibody (Stat5Y694-G11), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-Stat5 (Tyr694)

Applications

Flow Cytometry

Conjugate

APC

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P42229, P42230

Gene ID (Entrez)

20850, 6776

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr694 of human phospho Stat5.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

STAT5A

Clone

Stat5Y694-G11

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Gene Symbols

STAT5A

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

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Description

  • STAT5 alpha is a member of the STAT family of transcription factors
  • In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators
  • STAT5 alpha is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones
  • Activation of STAT5 alpha in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis
  • The mouse counterpart of STAT5 alpha is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this protein in cells
  • STAT5 alpha, along with STAT5 beta, were identified in mouse
  • The amino acid sequences of STAT5 alpha and STAT5 beta show 96% sequence similarity, and both proteins are co expressed in most tissues in virgin and lactating mice
  • However, differential accumulation of STAT5 alpha and STAT5 beta mRNA has been reported for both muscle and mammary tissue
  • STAT5 alpha is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

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Fischer Scientific

7215069

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Stat5 (Tyr694)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P42229, P42230

Gene ID (Entrez):
20850, 6776

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr694 of human phospho Stat5.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
STAT5A

Clone:
Stat5Y694-G11

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5

Gene Symbols:
STAT5A

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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7215070

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-SHP-1 (Tyr536)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P29350

Gene ID (Entrez):
5777

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
PTPN6

Clone:
Shp1Y536-2A7

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Gene Symbols:
PTPN6

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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7215071

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
O08586, P60484

Gene ID (Entrez):
19211, 5728

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
PTEN

Clone:
PTENS380T382383-E4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Gene Symbols:
PTEN

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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7215073

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-SLP76 (Tyr128)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q13094, Q60787

Gene ID (Entrez):
16822, 3937

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
LCP2

Clone:
SLP76Y128-3F8

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Gene Symbols:
LCP2

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody