7215224

Phospho-Stat1 (Tyr701) Recombinant Rabbit Monoclonal Antibody (Stat1Y701-3E6), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-Stat1 (Tyr701)

Applications

Flow Cytometry

Conjugate

APC

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P42224, P42225

Gene ID (Entrez)

20846, 6772

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr701 of human phospho Stat1.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

STAT1

Clone

Stat1Y701-3E6

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84

Gene Symbols

STAT1

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

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Description

  • STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors
  • STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6
  • STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism
  • Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure
  • The STAT1 gene is located on chromosome 2
  • STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors
  • After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes
  • Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile
  • STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1)
  • Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described.

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Fischer Scientific

7215224

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Stat1 (Tyr701)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P42224, P42225

Gene ID (Entrez):
20846, 6772

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr701 of human phospho Stat1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
STAT1

Clone:
Stat1Y701-3E6

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84

Gene Symbols:
STAT1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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7215225

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Jak3 (Tyr980, Tyr981)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P52333

Gene ID (Entrez):
3718

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr980/981 of human Jak3.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
JAK3

Clone:
JAK3Y980981-E10

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
Breast-JAK3; fae; JAK3; JAK-3; JAK3_HUMAN; JAK3B; JAKL; Janus kinase 3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); Janus kinase 3 protein-tyrosine kinase; Janus kinase 3, protein-tyrosine kinase; L JAK; Leukocyte janus kinase; LJAK; L-JAK; RATJAK3; Tyrosine-protein kinase JAK3; wil

Gene Symbols:
JAK3

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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7215228

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-MKK7 (Ser271, Thr275)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O14733

Gene ID (Entrez):
5609

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser271 and Thr275 of human MKK7.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
MAP2K7

Clone:
MKK7S271T275-R4F9

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
2; 5930412N11Rik; c-Jun N-terminal kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 7; EMBL:AAX61178.1}; JN; JNK kinase 2; JNK-activating kinase 2; JNKK; JNKK 2; Jnkk2; MAP kinase kinase 7; MAP2K4; map2k7; map2k7 {ECO:0000312; MAPK/ERK kinase 4; MAPK/ERK kinase 7; MAPKK 4; MAPKK 7; MAPKK7; MEK; MEK 4; MEK 7; Mek7; mitogen activated protein kinase kinase 7; mitogen-activated protein kinase kinase 7; Mkk7; PRKMK7; protein kinase, mitogen activated, kinase 7; SAPK kinase 1; SAPK kinase 4; SAPK/ERK kinase 1; SAPKK1; SAPKK-1; SAPKK4; SAPKK-4; SEK1; sek2; SKK4; Stress-activated protein kinase kinase 4

Gene Symbols:
MAP2K7

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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7215230

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-MAP2K4 (Ser257)

Applications:
Flow Cytometry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Non-human Primate

Gene Accession No.:
P45985, P47809

Gene ID (Entrez):
26398, 6416

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
MAP2K4

Clone:
SEK1MKK4S257-C5

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein

Gene Symbols:
MAP2K4

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody