7215277

Phospho-c-Cbl (Tyr774) Recombinant Rabbit Monoclonal Antibody (CblY774-R3B8), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-c-Cbl (Tyr774)

Applications

Flow Cytometry

Conjugate

APC

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P22681, P22682

Gene ID (Entrez)

12402, 867

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr774 of human phospho c-Cbl.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

Cbl

Clone

CblY774-R3B8

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL

Gene Symbols

Cbl

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Related Products

Img

Fischer Scientific

PIMA537350

--

Img

Fischer Scientific

PIMA537104

--

Img

Fischer Scientific

7215291

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

7215251

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

7215276

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

7215067

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

7215204

Rabbit Recombinant Monoclonal Antib...

Img

Fischer Scientific

PIMA537260

--

Description

  • Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation
  • Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed)
  • Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation
  • Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7215277

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-c-Cbl (Tyr774)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P22681, P22682

Gene ID (Entrez):
12402, 867

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr774 of human phospho c-Cbl.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Cbl

Clone:
CblY774-R3B8

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL

Gene Symbols:
Cbl

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215278

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-KSR1 (Ser392)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q61097, Q8IVT5

Gene ID (Entrez):
16706, 8844

Immunogen:
A synthetic phospho-peptide corresponding to residue surrounding Ser392 of human phospho KSR1.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
KSR1

Clone:
KSR1S392-3A4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Gene Symbols:
KSR1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215278

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-KSR1 (Ser392)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q61097, Q8IVT5

Gene ID (Entrez):
16706, 8844

Immunogen:
A synthetic phospho-peptide corresponding to residue surrounding Ser392 of human phospho KSR1.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
KSR1

Clone:
KSR1S392-3A4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Gene Symbols:
KSR1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215279

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PLCg2 (Tyr759)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P16885, Q8CIH5

Gene ID (Entrez):
234779, 5336

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr759 of human phospho PLCg2.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
Plcg2

Clone:
PLCG2Y759-G3

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2; APLAID; FCAS3; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-2; phospholipase C gamma 2; phospholipase C, gamma 2; phospholipase C, gamma 2 (phosphatidylinositol-specific); phospholipase C-gamma-2; Phospholipase C-IV; PLC gamma 2; PLC gamma2; PLC- gamma2; PLC gamma-2; PLCG2; Plcg-2; PLC-gamma; PLCgamma2; PLC-gamma-2; PLC-IV

Gene Symbols:
Plcg2

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody