7215073

Phospho-SLP76 (Tyr128) Recombinant Rabbit Monoclonal Antibody (SLP76Y128-3F8), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-SLP76 (Tyr128)

Applications

Flow Cytometry

Conjugate

APC

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

Q13094, Q60787

Gene ID (Entrez)

16822, 3937

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

LCP2

Clone

SLP76Y128-3F8

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Gene Symbols

LCP2

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

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Description

  • SLP-76 was originally identified as a substrate of the ZAP-70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat
  • The SLP-76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice
  • The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains
  • The NH2-terminus contains an acidic region that includes a PEST domain and several tyrosine residues which are phosphorylated following TCR ligation
  • SLP-76 also contains a central proline-rich domain and a COOH-terminal SH2 domain
  • A number of additional proteins have been identified that associate with SLP-76 both constitutively and inducibly following receptor ligation, supporting the notion that SLP-76 functions as an adaptor or scaffold protein
  • Studies using SLP-76 deficient T cell lines or mice have provided strong evidence that SLP-76 plays a positive role in promoting T cell development and activation as well as mast cell and platelet function.

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Img

Fischer Scientific

7215073

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-SLP76 (Tyr128)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q13094, Q60787

Gene ID (Entrez):
16822, 3937

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
LCP2

Clone:
SLP76Y128-3F8

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm

Gene Symbols:
LCP2

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215075

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-MAP2K4 (Ser257)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse, Non-human Primate, Rat

Gene Accession No.:
P45985, P47809

Gene ID (Entrez):
26398, 287398, 6416

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
MAP2K4

Clone:
SEK1MKK4S257-C5

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein

Gene Symbols:
MAP2K4

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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Fischer Scientific

7215077

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Chk1 (Ser345)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
O14757, O35280, Q91ZN7

Gene ID (Entrez):
1111, 12649, 140583

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser345 of human phospho Chk1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Chek1

Clone:
Chk1S345-R3F9

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W

Gene Symbols:
Chek1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215077

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Chk1 (Ser345)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
O14757, O35280, Q91ZN7

Gene ID (Entrez):
1111, 12649, 140583

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser345 of human phospho Chk1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Chek1

Clone:
Chk1S345-R3F9

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W

Gene Symbols:
Chek1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody