Phospho-MAP2K4 (Ser257) Recombinant Rabbit Monoclonal Antibody (SEK1MKK4S257-C5), APC, Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Phospho-MAP2K4 (Ser257)
Applications
Flow Cytometry
Conjugate
APC
Host Species
Rabbit
Target Species
Human, Mouse, Non-human Primate, Rat
Gene Accession No.
P45985, P47809
Gene ID (Entrez)
26398, 287398, 6416
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4.
Primary or Secondary
Primary
Content And Storage
4° C
Gene
MAP2K4
Clone
SEK1MKK4S257-C5
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias
C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein
Gene Symbols
MAP2K4
Isotype
IgG κ
Purification Method
Protein A/G
Product Type
Antibody
Description
- MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase 4) MEK4 or MKK4 is a dual specificity kinase of the STE7 family that phosphorylates and activates JNK1 and -2 as well as p38
- MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs
- MAP2K4 mediates a variety of physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines
- MAP2K4 is important for carcinogenesis; a loss-off-function mutation in MAP2K4 was found in lung and pancreatic tumors
- Conversely, a pro-oncogenic role was also found for MAP2K4.
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Antigen: Phospho-MAP2K4 (Ser257)
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rabbit
Target Species: Human, Mouse, Non-human Primate, Rat
Gene Accession No.: P45985, P47809
Gene ID (Entrez): 26398, 287398, 6416
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: MAP2K4
Clone: SEK1MKK4S257-C5
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein
Gene Symbols: MAP2K4
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen: Phospho-Chk1 (Ser345)
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rabbit
Target Species: Human, Mouse, Rat
Gene Accession No.: O14757, O35280, Q91ZN7
Gene ID (Entrez): 1111, 12649, 140583
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser345 of human phospho Chk1.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: Chek1
Clone: Chk1S345-R3F9
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Gene Symbols: Chek1
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
Antigen: Phospho-Chk1 (Ser345)
Applications: Flow Cytometry
Conjugate: APC
Host Species: Rabbit
Target Species: Human, Mouse, Rat
Gene Accession No.: O14757, O35280, Q91ZN7
Gene ID (Entrez): 1111, 12649, 140583
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser345 of human phospho Chk1.
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: Chek1
Clone: Chk1S345-R3F9
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Alias: C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Gene Symbols: Chek1
Isotype: IgG κ
Purification Method: Protein A/G
Product Type: Antibody
