7215103

Phospho-Chk2 (Thr68) Recombinant Rabbit Monoclonal Antibody (Chk2T68-D12), FITC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-Chk2 (Thr68)

Applications

Flow Cytometry

Conjugate

FITC

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

O96017, Q9Z265

Gene ID (Entrez)

11200, 50883

Immunogen

A synthetic phosphor-peptide corresponding to residues surrounding to Thr68 of human phospho Chk2.

Primary or Secondary

Primary

Content And Storage

4° C, store in dark

Gene

Chek2

Clone

Chk2T68-D12

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

CDS1; cds1 homolog; Checkpoint kinase 2; Checkpoint like protein CHK2; checkpoint-like protein CHK2; Chek2; Chk2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; CHK2 checkpoint homolog (S. pombe); Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; HuCds 1; HuCds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; Rad53; Rad53 homolog; RP11-436C9.1; Serine/threonine protein kinase Chk2; serine/threonine-protein kinase Chk2

Gene Symbols

Chek2

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Description

  • CHEK2 (CHK2) is a serine/threonine kinase and a component of the DNA damage checkpoint pathway
  • A mutation in CHK2 has been linked to cancer
  • CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in CHK2 are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

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Fischer Scientific

7215103

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Chk2 (Thr68)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
O96017, Q9Z265

Gene ID (Entrez):
11200, 50883

Immunogen:
A synthetic phosphor-peptide corresponding to residues surrounding to Thr68 of human phospho Chk2.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
Chek2

Clone:
Chk2T68-D12

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
CDS1; cds1 homolog; Checkpoint kinase 2; Checkpoint like protein CHK2; checkpoint-like protein CHK2; Chek2; Chk2; Chk2 (phospho T68); Chk2 (pThr68); CHK2 checkpoint homolog; CHK2 checkpoint homolog (S. pombe); Chk2 phospho; Chk2 phospho T68; del9; EC 2.7.11.1; hCds1; HuCds 1; HuCds1; kinase Chk2; LFS2; OTTHUMP00000199044; OTTHUMP00000199045; OTTHUMP00000199064; OTTHUMP00000199115; OTTHUMP00000199116; phospho Chk2 (T68); phospho Thr68 Chk2; PP1425; protein kinase Chk2; Rad53; Rad53 homolog; RP11-436C9.1; Serine/threonine protein kinase Chk2; serine/threonine-protein kinase Chk2

Gene Symbols:
Chek2

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215105

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PI3K p85/p55 (Tyr458, Tyr199)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
O00459, O08908, P26450, P27986, Q64143, Q92569

Gene ID (Entrez):
18708, 18709, 18710, 5295, 5296, 8503

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr458 of human phospho PI3K p85.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
PIK3R1

Clone:
PI3KY458-1A11

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
AA414954; AGM7; GRB1; IMD36; mitochondrial poly(ADP-ribose) glycohydrolase; MPPH; MPPH1; OTTHUMP00000009783; OTTHUMP00000009784; p50alpha; p55; p55alpha; p55-GAMMA; p55PIK; p85; p85alpha; p85-ALPHA; P85B; p85beta; p85-BETA; PARG; PARG99; phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55); phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase p55 subunit; phosphatidylinositol 3-kinase regulartory subunit polypeptide 2; phosphatidylinositol 3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase regulatory subunit gamma; phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 3 (p55, gamma); phosphatidylinositol 3-kinase-associated p-85 alpha; Phosphoinositide 3-kinase p85 (other splicing variants: p55 and p50); Phosphoinositide 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphoinositide-3-kinase regulatory subunit; phosphoinositide-3-kinase regulatory subunit 1; phosphoinositide-3-kinase regulatory subunit 2; phosphoinositide-3-kinase regulatory subunit 3; phosphoinositide-3-kinase regulatory subunit alpha; phosphoinositide-3-kinase regulatory subunit beta; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); phosphoinositide-3-kinase, regulatory subunit 2 (beta); phosphoinositide-3-kinase, regulatory subunit 3 (gamma); PI3K; PI3K regulatory subunit alpha; PI3K regulatory subunit beta; PI3K regulatory subunit gamma; PI3KA; PI3-kinase p85 subunit alpha; PI3-kinase p85 subunit beta; PI3-kinase p85 subunit gamma; PI3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit beta; PI3-kinase regulatory subunit gamma; PI3-kinase subunit p55-gamma; PI3-kinase subunit p85-alpha; PI3-kinase subunit p85-beta; Pik3r1; PIK3R2; Pik3r3; poly (ADP-ribose) glycohydrolase; poly(ADP-ribose) glycohydrolase; poly(ADP-ribose) glycohydrolase 60 kDa isoform; polypeptide 3; ptdIns-3-kinase p85-alpha; ptdIns-3-kinase p85-beta; ptdIns-3-kinase p85-gamma; ptdIns-3-kinase regulatory subunit alpha; ptdIns-3-kinase regulatory subunit beta; ptdIns-3-kinase regulatory subunit gamma; ptdIns-3-kinase regulatory subunit p55-gamma; PtdIns-3-kinase regulatory subunit p85-al; ptdIns-3-kinase regulatory subunit p85-alpha; ptdIns-3-kinase regulatory subunit p85-beta; RP4-533D7.2

Gene Symbols:
PIK3R1, Pik3r2, PIK3R3

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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Fischer Scientific

7215106

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-MCM2 (Ser139)

Applications:
Flow Cytometry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P49736, P97310

Gene ID (Entrez):
17216, 312538, 4171

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser139 of human phospho MCM2.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
MCM2

Clone:
MCM2S139-B12

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
AA959861; AW476101; BM28; CCNL1; cdc19; CDCL1; cell devision cycle-like 1; cyclin-like 1; D3S3194; DFNA70; DNA replication licensing factor MCM2; Kiaa0030; MCM DNA helicase complex subunit MCM2; Mcm2; Mcmd2; MGC10606; mini chromosome maintenance deficient 2; minichromosome maintenance complex component 2; minichromosome maintenance deficient 2 (mitotin); minichromosome maintenance deficient 2 mitotin; minichromosome maintenance deficient 2 mitotin (S. cerevisiae); Minichromosome maintenance protein 2; Minichromosome maintenance protein 2 homolog; MITOTIN; mKIAA0030; Nuclear protein BM28; YBL023C; YBL0438

Gene Symbols:
MCM2

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215109

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Aurora A/B/C (Thr288, Thr232, Thr198)

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O14965, Q96GD4, Q9UQB9

Gene ID (Entrez):
6790, 6795, 9212

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding human Aurora A (Thr288)/Aurora B (Thr232)/Aurora C (Thr198).

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
Aurka

Clone:
AuroraABC-CC12

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
Aik; Aik2; AIM1; AIM-1; Airk; AIRK1; AIRK2; AL022959; ARK1; ARK-1; ARK2; ARK-2; AU019385; AURA; AurB; AURKA; AURKB; aurkb-sv1; aurkb-sv2; Aurora 1; aurora 2; aurora A; aurora- and Ipl1-like midbody-associated protein 1; aurora B; aurora family kinase 1; Aurora kinase A; aurora kinase B; aurora kinase B-Sv1; aurora kinase B-Sv2; aurora/IPL1-like kinase; aurora/IPL1-related kinase 1; Aurora/IPL1-related kinase 2; aurora-1; aurora-A; aurora-B; aurora-related kinase 1; aurora-related kinase 2; AW539821; Ayk1; Breast tumor-amplified kinase; Btak; IAK; IAK1; IPL1; ipl1- and aurora-related kinase 1; PPP1R47; PPP1R48; protein phosphatase 1, regulatory subunit 47; protein phosphatase 1, regulatory subunit 48; ratAurA; serine/threonine kinase 12; serine/threonine kinase 5; serine/threonine kinase 6; serine/threonine protein kinase 15; serine/threonine protein kinase 6; serine/threonine-protein kinase 12; Serine/threonine-protein kinase 15; Serine/threonine-protein kinase 5; serine/threonine-prot

Gene Symbols:
Aurka, Aurkb, AURKC

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody