7215140

Phospho-Ask1 (Ser83) Recombinant Rabbit Monoclonal Antibody (Ask1S83-G4), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Phospho-Ask1 (Ser83)

Applications

Flow Cytometry

Conjugate

APC

Host Species

Rabbit

Target Species

Human, Mouse, Rat

Gene Accession No.

O35099, Q99683

Gene ID (Entrez)

26408, 365057, 4217

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Ser83 of human phospho Ask1.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

MAP3K5

Clone

Ask1S83-G4

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4

Gene Symbols

MAP3K5

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Description

  • MAP3K5 (ASK1) is a serine/threonine kinase that is abundantly expressed in human heart and pancreas and are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses
  • A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5
  • ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively
  • ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx
  • Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis
  • ASK1 is expressed in variety of human and mouse tissues.

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Img

Fischer Scientific

7215140

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Ask1 (Ser83)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
O35099, Q99683

Gene ID (Entrez):
26408, 365057, 4217

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser83 of human phospho Ask1.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
MAP3K5

Clone:
Ask1S83-G4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4

Gene Symbols:
MAP3K5

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215141

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-mTOR (Ser2448)

Applications:
Flow Cytometry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P42345, Q9JLN9

Gene ID (Entrez):
2475, 56717

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser2448 of human phospho mTOR.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
MTOR

Clone:
mTORS2448-E11

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS

Gene Symbols:
MTOR

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215143

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PKC gamma (Thr514)

Applications:
Flow Cytometry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P05129, P63318, P63319

Gene ID (Entrez):
18752, 24681, 5582

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr514 of human phospho PKC gamma.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
PRKCG

Clone:
PKCgT514-PF4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
PKC; Pkcc; PKCG; PKCgamma; PKC-gamma; PKCI; Prkc; Prkcc; PRKCG; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, gamma; RATPKCI; SCA14

Gene Symbols:
PRKCG

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Img

Fischer Scientific

7215144

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PKC gamma (Thr514)

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P05129, P63318, P63319

Gene ID (Entrez):
18752, 24681, 5582

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr514 of human phospho PKC gamma.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
PRKCG

Clone:
PKCgT514-PF4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
PKC; Pkcc; PKCG; PKCgamma; PKC-gamma; PKCI; Prkc; Prkcc; PRKCG; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, gamma; RATPKCI; SCA14

Gene Symbols:
PRKCG

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody