7215143

Phospho-PKC gamma (Thr514) Recombinant Rabbit Monoclonal Antibody (PKCgT514-PF4), Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-PKC gamma (Thr514)

Concentration

0.5 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias

PKC; Pkcc; PKCG; PKCgamma; PKC-gamma; PKCI; Prkc; Prkcc; PRKCG; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, gamma; RATPKCI; SCA14

Gene Symbols

PRKCG

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

Clone

PKCgT514-PF4

Applications

Flow Cytometry, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse, Rat

Gene Accession No.

P05129, P63318, P63319

Gene ID (Entrez)

18752, 24681, 5582

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Thr514 of human phospho PKC gamma.

Primary or Secondary

Primary

Content And Storage

-20°C

Gene

PRKCG

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Description

  • The PKC family of serine/threonine kinases, including PRKCG (PKC gamma), is activated intracellularly by signal transduction pathways
  • In humans, at least 12 different PKC polypeptides have been identified
  • These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity
  • PKC alpha, beta I, beta II, and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent
  • Protein kinase C can be activated by calcium and second messenger diacylglycerol
  • PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways
  • PKC also serve as major receptors for phorbol esters, a class of tumor promoters
  • Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells
  • PKC gamma is one of the PKC family members
  • This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons
  • It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase
  • Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development
  • Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).

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Img

Fischer Scientific

7215143

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PKC gamma (Thr514)

Concentration:
0.5 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
PKC; Pkcc; PKCG; PKCgamma; PKC-gamma; PKCI; Prkc; Prkcc; PRKCG; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, gamma; RATPKCI; SCA14

Gene Symbols:
PRKCG

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
PKCgT514-PF4

Applications:
Flow Cytometry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P05129, P63318, P63319

Gene ID (Entrez):
18752, 24681, 5582

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr514 of human phospho PKC gamma.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
PRKCG

Img

Fischer Scientific

7215144

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PKC gamma (Thr514)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
PKC; Pkcc; PKCG; PKCgamma; PKC-gamma; PKCI; Prkc; Prkcc; PRKCG; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, gamma; RATPKCI; SCA14

Gene Symbols:
PRKCG

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
PKCgT514-PF4

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P05129, P63318, P63319

Gene ID (Entrez):
18752, 24681, 5582

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr514 of human phospho PKC gamma.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
PRKCG

Img

Fischer Scientific

7215144

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PKC gamma (Thr514)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
PKC; Pkcc; PKCG; PKCgamma; PKC-gamma; PKCI; Prkc; Prkcc; PRKCG; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, gamma; RATPKCI; SCA14

Gene Symbols:
PRKCG

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
PKCgT514-PF4

Applications:
Flow Cytometry

Conjugate:
FITC

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P05129, P63318, P63319

Gene ID (Entrez):
18752, 24681, 5582

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr514 of human phospho PKC gamma.

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark

Gene:
PRKCG

Img

Fischer Scientific

7215145

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PKC gamma (Thr514)

Concentration:
__

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
PKC; Pkcc; PKCG; PKCgamma; PKC-gamma; PKCI; Prkc; Prkcc; PRKCG; protein kinase C gamma; protein kinase C gamma type; protein kinase C type I (gamma type); protein kinase C, gamma; RATPKCI; SCA14

Gene Symbols:
PRKCG

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

Clone:
PKCgT514-PF4

Applications:
Flow Cytometry

Conjugate:
PE

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P05129, P63318, P63319

Gene ID (Entrez):
18752, 24681, 5582

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr514 of human phospho PKC gamma.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
PRKCG