PIMA537128

Phospho-SHP-1 (Tyr536) Recombinant Rabbit Monoclonal Antibody (Shp1Y536-2A7), Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA537128-Each-of-1 In Stock ₹ 60,148.68

PIMA537128 - Each of 1

₹ 60,148.68

In Stock

Quantity

1

Base Price: ₹ 60,148.68

GST (18%): ₹ 10,826.762

Total Price: ₹ 70,975.442

Antigen

Phospho-SHP-1 (Tyr536)

Classification

Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.

P29350

Gene Symbols

PTPN6

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.

Quantity

200 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG κ

Applications

Flow Cytometry

Clone

Shp1Y536-2A7

Conjugate

Unconjugated

Gene

PTPN6

Gene Alias

70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

5777

Content And Storage

-20°C

Form

Liquid

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Description

  • SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
  • The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
  • SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
  • In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
  • Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
  • Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.

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Img

Fischer Scientific

PIMA537128

--


Antigen:
Phospho-SHP-1 (Tyr536)

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Accession No.:
P29350

Gene Symbols:
PTPN6

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
Shp1Y536-2A7

Conjugate:
Unconjugated

Gene:
PTPN6

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5777

Content And Storage:
-20°C

Form:
Liquid

Img

Fischer Scientific

PIMA537129

--


Antigen:
Phospho-SHP-1 (Tyr536)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
P29350

Gene Symbols:
PTPN6

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
Shp1Y536-2A7

Conjugate:
PE

Gene:
PTPN6

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5777

Content And Storage:
4° C

Form:
Liquid

Img

Fischer Scientific

PIMA537130

--


Antigen:
Phospho-SHP-1 (Tyr536)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
P29350

Gene Symbols:
PTPN6

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
Shp1Y536-2A7

Conjugate:
FITC

Gene:
PTPN6

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5777

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Fischer Scientific

PIMA537131

--


Antigen:
Phospho-SHP-1 (Tyr536)

Classification:
Monoclonal

Concentration:
__

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Accession No.:
P29350

Gene Symbols:
PTPN6

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
Shp1Y536-2A7

Conjugate:
APC

Gene:
PTPN6

Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
5777

Content And Storage:
4° C

Form:
Liquid