PIMA537376
Phospho-SHP-1 (Tyr536) Recombinant Rabbit Monoclonal Antibody (Shp1Y536-2A7), FITC, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537376-Each-of-1 | In Stock | ₹ 18,994.32 |
PIMA537376 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 18,994.32
GST (18%): ₹ 3,418.978
Total Price: ₹ 22,413.298
Antigen
Phospho-SHP-1 (Tyr536)
Classification
Monoclonal
Conjugate
FITC
Gene
PTPN6
Gene Alias
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
5777
Content And Storage
4° C, store in dark
Form
Liquid
Applications
Flow Cytometry
Clone
Shp1Y536-2A7
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.
P29350
Gene Symbols
PTPN6
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.
Quantity
10 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG κ
Related Products
Description
- SHP-1 (PTPN6) is a non-receptor protein tyrosine phosphatase that is expressed primarily in hematopoietic cells
- The enzyme is composed of two SH2 domains, a tyrosine phosphatase catalytic domain, and a carboxy-terminal regulatory domain
- SHP-1 removes phosphates from target proteins to downregulate several tyrosine kinase-regulated pathways
- In hematopoietic cells, the amino-terminal SH2 domain of SHP-1 binds to tyrosine phosphorylated erythropoietin receptors (EpoR) to negatively regulate hematopoietic growth
- Overexpression of SHP-1 in epithelial cells results in dephosphorylation of the Ros receptor tyrosine kinase and subsequent downregulation of Ros-dependent cell proliferation and transformation
- Following ligand binding in myeloid cells, SHP-1 associates with the IL-3R beta chain and downregulates IL-3-induced tyrosine phosphorylation and cell proliferation.
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Antigen: Phospho-SHP-1 (Tyr536)
Classification: Monoclonal
Conjugate: FITC
Gene: PTPN6
Gene Alias: 70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 5777
Content And Storage: 4° C, store in dark
Form: Liquid
Applications: Flow Cytometry
Clone: Shp1Y536-2A7
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: P29350
Gene Symbols: PTPN6
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.
Quantity: 10 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-SHP-1 (Tyr536)
Classification:
Monoclonal
Conjugate:
FITC
Gene:
PTPN6
Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
5777
Content And Storage:
4° C, store in dark
Form:
Liquid
Applications:
Flow Cytometry
Clone:
Shp1Y536-2A7
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
P29350
Gene Symbols:
PTPN6
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.
Quantity:
10 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-SHP-1 (Tyr536)
Classification: Monoclonal
Conjugate: APC
Gene: PTPN6
Gene Alias: 70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 5777
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: Shp1Y536-2A7
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: P29350
Gene Symbols: PTPN6
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.
Quantity: 10 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-SHP-1 (Tyr536)
Classification:
Monoclonal
Conjugate:
APC
Gene:
PTPN6
Gene Alias:
70Z-SHP; EC 3.1.3.48; hcp; Hcph; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; me; motheaten; protein tyrosine phosphatase, non-receptor type 6; protein-tyrosine phosphatase 1C; Protein-tyrosine phosphatase SHP-1; PTN6; Ptp1C; PTP-1C; Ptph6; PTPN6; PTPTY-42; SH2 phosphatase 1; SHP1; Shp-1; SHP-1L; SH-PTP1; Tyrosine-protein phosphatase non-receptor type 6
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
5777
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
Shp1Y536-2A7
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
P29350
Gene Symbols:
PTPN6
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr536 of human phospho Shp1.
Quantity:
10 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-MAPK9 (Thr183, Tyr185)
Classification: Monoclonal
Conjugate: FITC
Gene: MAPK9
Gene Alias: AI851083; c-Jun kinase 2; c-Jun N-terminal kinase 2; I79_012561; JNK; JNK/SAPK alpha; JNK1; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-46; JNK-55; Jun kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAPK 10; MAPK 9; MAPK10; MAPK8; Mapk9; mitogen activated protein kinase 9; mitogen-activated protein kinase 9; OTTHUMP00000161542; OTTHUMP00000161543; p54a; p54-alpha; p54aSAPK; PRKM8; PRKM9; protein kinase, mitogen-activated 9; SAPK; SAPK1; SAPK1a; SAPK1c; SAPK-alpha; stress activated protein kinase alpha II; stress-activated protein kinase 1a; Stress-activated protein kinase JNK2
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 5601
Content And Storage: 4° C, store in dark
Form: Liquid
Applications: Flow Cytometry
Clone: SAPKT183Y185-A11
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: P45984
Gene Symbols: MAPK9
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Thr183/Tyr185 of human phospho SAPK/JNK.
Quantity: 10 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-MAPK9 (Thr183, Tyr185)
Classification:
Monoclonal
Conjugate:
FITC
Gene:
MAPK9
Gene Alias:
AI851083; c-Jun kinase 2; c-Jun N-terminal kinase 2; I79_012561; JNK; JNK/SAPK alpha; JNK1; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-46; JNK-55; Jun kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAPK 10; MAPK 9; MAPK10; MAPK8; Mapk9; mitogen activated protein kinase 9; mitogen-activated protein kinase 9; OTTHUMP00000161542; OTTHUMP00000161543; p54a; p54-alpha; p54aSAPK; PRKM8; PRKM9; protein kinase, mitogen-activated 9; SAPK; SAPK1; SAPK1a; SAPK1c; SAPK-alpha; stress activated protein kinase alpha II; stress-activated protein kinase 1a; Stress-activated protein kinase JNK2
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
5601
Content And Storage:
4° C, store in dark
Form:
Liquid
Applications:
Flow Cytometry
Clone:
SAPKT183Y185-A11
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
P45984
Gene Symbols:
MAPK9
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Thr183/Tyr185 of human phospho SAPK/JNK.
Quantity:
10 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-MAP2K4 (Ser257)
Classification: Monoclonal
Conjugate: Unconjugated
Gene: MAP2K4
Gene Alias: C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 26398, 6416
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Western Blot
Clone: SEK1MKK4S257-C5
Formulation: PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.: P45985, P47809
Gene Symbols: MAP2K4
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-MAP2K4 (Ser257)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
MAP2K4
Gene Alias:
C-JUN N-terminal kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4; dual specificity mitogen-activated protein kinase kinase 4a; JNK kinase 1; JNK-activated kinase 1; JNK-activating kinase 1; JNKK; JNKK 1; JNKK1; MAP kinase activator 2; MAP kinase kinase 4; Map2k4; map2k4.L; map2k4a; map2k4-a; map2k4-b; MAP2K4delta; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; MEK 4; MEK4; mitogen activated protein kinase kinase 4; mitogen activated protein kinase kinase 4, variant 1; mitogen-activated protein kinase kinase 4; mitogen-activated protein kinase kinase 4 L homeolog; mitogen-activated protein kinase kinase 4a; MKK4; mkk4a; MKK4A-l; PRKMK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPK/Erk/kinase 1; SAPKK1; SAPKK-1; Sek1; Serk1; Skk1; Stress-activated protein kinase kinase 1; XELAEV_18044157mg; XMEK2; zgc:136500; zMKK4 protein
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
26398, 6416
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Western Blot
Clone:
SEK1MKK4S257-C5
Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P45985, P47809
Gene Symbols:
MAP2K4
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG κ