7215131

Phospho-Shp2 (Tyr580) Recombinant Rabbit Monoclonal Antibody (Shp2Y580-4A2), APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Phospho-Shp2 (Tyr580)

Applications

Flow Cytometry

Conjugate

APC

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

P35235, Q06124

Gene ID (Entrez)

19247, 5781

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr580 of human phospho Shp2.

Primary or Secondary

Primary

Content And Storage

4° C

Gene

PTPN11

Clone

Shp2Y580-4A2

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias

2700084A17Rik; AW536184; bptp3; CFC; cSH-PTP2; encodes catalytic domain; HCP; HGNC:9644; JMML; METCDS; MGC14433; Noonan syndrome 1; ns1; null; OTTHUMP00000166108; phosphotyrosyl-protein phosphatase; protein tyrosine phosphatase non-receptor type 11; protein tyrosine phosphatase SH-PTP2; protein tyrosine phosphatase, non-receptor type 11; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); protein tyrosine phosphatase, non-receptor type 11 S homeolog; protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; protein-tyrosine phosphatase SYP; PTP1C; PTP1D; PTP-1D; ptp-2; PTP2C; PTP-2C; Ptpn11; ptpn11.S; ptpn11-a; ptpn11-b; SAP-2; SH2 domain-containing protein tyrosine phosphatase-2; Shp2; shp-2; SHPTP2; SH-PTP2; SH-PTP2 protein tyrosine phosphatase non-receptor type 11; SH-PTP2 protein tyrosine phosphatase, non-receptor type 11; SH-PTP3; Syp; Tyrosine-protein phosphatase non-receptor type 11; XELAEV_18010676mg

Gene Symbols

PTPN11

Isotype

IgG κ

Purification Method

Protein A/G

Product Type

Antibody

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Description

  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family
  • PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
  • This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates
  • This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration
  • Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

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Fischer Scientific

7215131

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Shp2 (Tyr580)

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P35235, Q06124

Gene ID (Entrez):
19247, 5781

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr580 of human phospho Shp2.

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
PTPN11

Clone:
Shp2Y580-4A2

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.20% BSA and 0.09% sodium azide

Gene Alias:
2700084A17Rik; AW536184; bptp3; CFC; cSH-PTP2; encodes catalytic domain; HCP; HGNC:9644; JMML; METCDS; MGC14433; Noonan syndrome 1; ns1; null; OTTHUMP00000166108; phosphotyrosyl-protein phosphatase; protein tyrosine phosphatase non-receptor type 11; protein tyrosine phosphatase SH-PTP2; protein tyrosine phosphatase, non-receptor type 11; protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1); protein tyrosine phosphatase, non-receptor type 11 S homeolog; protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C; protein-tyrosine phosphatase SYP; PTP1C; PTP1D; PTP-1D; ptp-2; PTP2C; PTP-2C; Ptpn11; ptpn11.S; ptpn11-a; ptpn11-b; SAP-2; SH2 domain-containing protein tyrosine phosphatase-2; Shp2; shp-2; SHPTP2; SH-PTP2; SH-PTP2 protein tyrosine phosphatase non-receptor type 11; SH-PTP2 protein tyrosine phosphatase, non-receptor type 11; SH-PTP3; Syp; Tyrosine-protein phosphatase non-receptor type 11; XELAEV_18010676mg

Gene Symbols:
PTPN11

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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7215134

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-Jak2 (Tyr1007, Tyr1008)

Applications:
Flow Cytometry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O60674

Gene ID (Entrez):
3717

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr1007/Tyr1008 of human phospho Jak2.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
JAK2

Clone:
Jak2Y10071008-PB6

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
EC 2.7.10.2; Fd17; JAK 2; JAK2; JAK-2; Janus kinase 2; Janus kinase 2 (a protein tyrosine kinase); JTK 10; JTK10; kinase Jak2; THCYT3; Tyrosine-protein kinase JAK2

Gene Symbols:
JAK2

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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7215136

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PTEN (Ser380)

Applications:
Flow Cytometry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
O08586, P60484

Gene ID (Entrez):
19211, 5728

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 of human phospho PTEN.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
PTEN

Clone:
PTENS380-NA9

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1

Gene Symbols:
PTEN

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody

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7215137

Rabbit Recombinant Monoclonal Antib...


Antigen:
Phospho-PLCg1 (Tyr783)

Applications:
Flow Cytometry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
P19174, Q62077

Gene ID (Entrez):
18803, 5335

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCg1.

Primary or Secondary:
Primary

Content And Storage:
-20°C

Gene:
PLCG1

Clone:
PLCG1Y783-C4

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide

Gene Alias:
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase

Gene Symbols:
PLCG1

Isotype:
IgG κ

Purification Method:
Protein A/G

Product Type:
Antibody